ATE201013T1 - Triglyceride und ethylester von phenylalkansäuren und phenylalkensäuren zur behandlung verschiedener erkrankungen - Google Patents
Triglyceride und ethylester von phenylalkansäuren und phenylalkensäuren zur behandlung verschiedener erkrankungenInfo
- Publication number
- ATE201013T1 ATE201013T1 AT96904495T AT96904495T ATE201013T1 AT E201013 T1 ATE201013 T1 AT E201013T1 AT 96904495 T AT96904495 T AT 96904495T AT 96904495 T AT96904495 T AT 96904495T AT E201013 T1 ATE201013 T1 AT E201013T1
- Authority
- AT
- Austria
- Prior art keywords
- acids
- phenylalkeneic
- phenylalkaneous
- ethylesters
- triglycerides
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 6
- 150000007513 acids Chemical class 0.000 title abstract 4
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 150000003626 triacylglycerols Chemical class 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 229940002612 prodrug Drugs 0.000 abstract 2
- 239000000651 prodrug Substances 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 238000009825 accumulation Methods 0.000 abstract 1
- IPBVNPXQWQGGJP-UHFFFAOYSA-N acetic acid phenyl ester Natural products CC(=O)OC1=CC=CC=C1 IPBVNPXQWQGGJP-UHFFFAOYSA-N 0.000 abstract 1
- 208000007502 anemia Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000000039 congener Substances 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000004494 ethyl ester group Chemical group 0.000 abstract 1
- 208000034737 hemoglobinopathy Diseases 0.000 abstract 1
- 208000018337 inherited hemoglobinopathy Diseases 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229940049953 phenylacetate Drugs 0.000 abstract 1
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical compound OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
- C07C69/618—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety having unsaturation outside the six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38493595A | 1995-02-07 | 1995-02-07 | |
| PCT/US1996/000940 WO1996024571A1 (en) | 1995-02-07 | 1996-02-06 | Triglycerides and ethyl esters of phenylalkanoic acid and phenylalkenoic acid useful in treatment of various disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE201013T1 true ATE201013T1 (de) | 2001-05-15 |
Family
ID=23519346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96904495T ATE201013T1 (de) | 1995-02-07 | 1996-02-06 | Triglyceride und ethylester von phenylalkansäuren und phenylalkensäuren zur behandlung verschiedener erkrankungen |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US5968979A (de) |
| EP (1) | EP0858441B1 (de) |
| AT (1) | ATE201013T1 (de) |
| AU (1) | AU4858796A (de) |
| CA (1) | CA2212047C (de) |
| DE (1) | DE69612755T2 (de) |
| ES (1) | ES2157422T3 (de) |
| FR (1) | FR16C0003I2 (de) |
| WO (1) | WO1996024571A1 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6642543B1 (en) | 2000-09-26 | 2003-11-04 | The Board Of Trustees Of The Leland Stanford Junior University | Thin and thick gate oxide transistors on a functional block of a CMOS circuit residing within the core of an IC chip |
| US7842727B2 (en) | 2001-03-27 | 2010-11-30 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
| US8026280B2 (en) | 2001-03-27 | 2011-09-27 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
| US6495719B2 (en) | 2001-03-27 | 2002-12-17 | Circagen Pharmaceutical | Histone deacetylase inhibitors |
| US7312247B2 (en) | 2001-03-27 | 2007-12-25 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
| US20040229948A1 (en) * | 2002-04-12 | 2004-11-18 | Summar Marshall L. | Method for preventing hepatic encephalopathic episodes |
| US20030195255A1 (en) * | 2002-04-12 | 2003-10-16 | Summar Marshall L. | Method for treating hepatic encephalopathies |
| EP1511477A4 (de) | 2002-05-22 | 2008-04-09 | Errant Gene Therapeutics Llc | Histondeacetylase-hemmer auf basis von alpha-ketoepoxid-verbindungen |
| CA2506504A1 (en) | 2002-11-20 | 2004-06-03 | Errant Gene Therapeutics, Llc | Treatment of lung cells with histone deacetylase inhibitors |
| US20090260743A1 (en) * | 2003-11-21 | 2009-10-22 | William David Mawby | Tire manufacturing method for improving the uniformity of a tire |
| CA2587013A1 (en) * | 2004-11-08 | 2006-05-18 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
| CA2735218A1 (en) * | 2008-04-29 | 2009-11-05 | Ucyclyd Pharma, Inc. | Methods of treatment using ammonia-scavenging drugs |
| ES2593378T3 (es) * | 2008-08-29 | 2016-12-09 | Horizon Therapeutics, Llc | Métodos de tratamiento usando fármacos de secuestro de ammonia |
| AU2012316750B2 (en) | 2011-09-30 | 2017-08-31 | Immedica Pharma Ab | Methods of therapeutic monitoring of nitrogen scavenging drugs |
| MX365302B (es) | 2012-04-20 | 2019-05-29 | Horizon Therapeutics Llc | Métodos de monitoreo terapéutico del gliceril tri- [ 4-fenilbutirato] (hpn-100) para usarse en el tratamiento de trastornos de retención de nitrógeno. |
| DK2922576T3 (en) | 2012-11-21 | 2018-01-15 | Horizon Therapeutics Llc | PROCEDURES FOR THE ADMINISTRATION AND EVALUATION OF NITROGEN RINSE MEDICINES FOR TREATING HEPATIC ENCYPHALOPATHY |
| SI2986325T1 (sl) | 2013-10-14 | 2020-02-28 | Immedica Pharma Ab | Postopki zdravljenja motenj ciklusa sečnine |
| IN2013MU03442A (de) | 2013-10-30 | 2015-07-17 | Lupin Ltd | |
| CA2929688C (en) | 2013-11-14 | 2023-06-13 | Ultragenyx Pharmaceutical Inc. | Solid compositions of triglycerides and uses thereof |
| ES2861594T3 (es) | 2014-04-30 | 2021-10-06 | Univ Johns Hopkins | Composiciones de dendrímeros y su uso en el tratamiento de enfermedades del ojo |
| US10918720B2 (en) | 2014-08-13 | 2021-02-16 | The Johns Hopkins University | Selective dendrimer delivery to brain tumors |
| JP7088473B2 (ja) | 2015-10-29 | 2022-06-21 | ザ・ジョンズ・ホプキンス・ユニバーシティー | ペルオキシソーム障害および白質ジストロフィーの処置のための組成物および方法 |
| US9914692B2 (en) | 2016-05-25 | 2018-03-13 | Horizon Therapeutics, Llc | Procedure for the preparation of 4-phenyl butyrate and uses thereof |
| US10668040B2 (en) | 2017-09-11 | 2020-06-02 | Horizon Therapeutics, Llc | Treatment of urea cycle disorders in neonates and infants |
| US11612660B2 (en) | 2019-12-04 | 2023-03-28 | Ashvattha Therapeutics, Inc. | Dendrimer compositions and methods for drug delivery to the eye |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5879657A (en) * | 1993-03-30 | 1999-03-09 | The Dupont Merck Pharmaceutical Company | Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders |
-
1996
- 1996-02-06 WO PCT/US1996/000940 patent/WO1996024571A1/en active IP Right Grant
- 1996-02-06 EP EP96904495A patent/EP0858441B1/de not_active Expired - Lifetime
- 1996-02-06 DE DE69612755T patent/DE69612755T2/de not_active Expired - Lifetime
- 1996-02-06 AT AT96904495T patent/ATE201013T1/de not_active IP Right Cessation
- 1996-02-06 ES ES96904495T patent/ES2157422T3/es not_active Expired - Lifetime
- 1996-02-06 AU AU48587/96A patent/AU4858796A/en not_active Abandoned
- 1996-02-06 CA CA2212047A patent/CA2212047C/en not_active Expired - Fee Related
-
1998
- 1998-01-13 US US09/006,432 patent/US5968979A/en not_active Expired - Lifetime
-
1999
- 1999-05-25 US US09/317,901 patent/US6060510A/en not_active Expired - Lifetime
- 1999-05-25 US US09/317,900 patent/US6083984A/en not_active Expired - Lifetime
-
2016
- 2016-02-03 FR FR16C0003C patent/FR16C0003I2/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| FR16C0003I1 (de) | 2016-03-25 |
| DE69612755T2 (de) | 2001-08-23 |
| CA2212047A1 (en) | 1996-08-15 |
| EP0858441A4 (de) | 1998-08-19 |
| AU4858796A (en) | 1996-08-27 |
| US6083984A (en) | 2000-07-04 |
| WO1996024571A1 (en) | 1996-08-15 |
| US5968979A (en) | 1999-10-19 |
| EP0858441A1 (de) | 1998-08-19 |
| ES2157422T3 (es) | 2001-08-16 |
| EP0858441B1 (de) | 2001-05-09 |
| US6060510A (en) | 2000-05-09 |
| CA2212047C (en) | 2010-11-16 |
| FR16C0003I2 (fr) | 2016-06-24 |
| DE69612755D1 (de) | 2001-06-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |