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ATE195513T1 - 22-thiavitamin-d3-derivate - Google Patents

22-thiavitamin-d3-derivate

Info

Publication number
ATE195513T1
ATE195513T1 AT95914550T AT95914550T ATE195513T1 AT E195513 T1 ATE195513 T1 AT E195513T1 AT 95914550 T AT95914550 T AT 95914550T AT 95914550 T AT95914550 T AT 95914550T AT E195513 T1 ATE195513 T1 AT E195513T1
Authority
AT
Austria
Prior art keywords
hydroxy
represents hydrogen
thiavitamin
derivatives
vitamin
Prior art date
Application number
AT95914550T
Other languages
English (en)
Inventor
Noboru Kubodera
Akira Kawase
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE195513T1 publication Critical patent/ATE195513T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036Nitrogen-containing hetero ring
    • C07J71/0042Nitrogen only
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
AT95914550T 1994-04-11 1995-04-10 22-thiavitamin-d3-derivate ATE195513T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10736694 1994-04-11
PCT/JP1995/000699 WO1995027697A1 (fr) 1994-04-11 1995-04-10 Derive de la 22-thiavitamine d¿3?

Publications (1)

Publication Number Publication Date
ATE195513T1 true ATE195513T1 (de) 2000-09-15

Family

ID=14457272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95914550T ATE195513T1 (de) 1994-04-11 1995-04-10 22-thiavitamin-d3-derivate

Country Status (14)

Country Link
US (1) US5824811A (de)
EP (1) EP0755922B1 (de)
KR (1) KR100244060B1 (de)
CN (1) CN1046502C (de)
AT (1) ATE195513T1 (de)
AU (1) AU2148295A (de)
BR (1) BR9507355A (de)
DE (1) DE69518410T2 (de)
DK (1) DK0755922T3 (de)
ES (1) ES2150560T3 (de)
GR (1) GR3034322T3 (de)
PT (1) PT755922E (de)
RU (1) RU2142941C1 (de)
WO (1) WO1995027697A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9226877D0 (en) * 1992-12-23 1993-02-17 Leo Pharm Prod Ltd Chemical compounds
WO1997024126A1 (fr) 1995-12-28 1997-07-10 Chugai Seiyaku Kabushiki Kaisha Inhibiteurs des metastases de tumeurs malignes
US6869940B2 (en) 1995-12-28 2005-03-22 Chugai Seiyaku Kabushiki Kaisha Malignant tumor metastasis inhibitors
US6184398B1 (en) * 1996-12-20 2001-02-06 Chugai Seiyaku Kabushiki Kaisha 16-ene-vitamin D derivatives
IL161890A0 (en) * 1996-12-20 2005-11-20 Chugai Pharmaceutical Co Ltd 16-Ene-vitamin d derivatives
EP0981523B1 (de) * 1997-05-16 2005-12-07 Woman & Infants Hospital Zyklische äther vitamin d3 verbindungen, 1alfa(oh) 3-epi-vitamin d3 verbindungen und deren verwendungen
AU6730600A (en) * 1999-08-27 2001-03-26 Chugai Seiyaku Kabushiki Kaisha Vitamin d derivatives having substituents at the 2alpha-position
US6899911B2 (en) * 2000-04-05 2005-05-31 International Flavors & Fragrances, Inc. Ethyl 4-(thioacetoxy)butyrate as a flavoring agent and methods for preparing and using same
GB2364231A (en) * 2000-04-05 2002-01-23 Bush Boake Allen Ltd Flavouring agent
US7074777B2 (en) 2000-04-19 2006-07-11 Chugai Seiyaku Kabushiki Kaisha Vitamin D derivatives
CN100469764C (zh) 2000-06-15 2009-03-18 中外制药株式会社 维生素d衍生物
US20100196308A1 (en) 2009-01-27 2010-08-05 Jimenez Joaquin J Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
BR112012003372A2 (pt) 2009-08-14 2019-09-24 Berg Biosystems Llc vitamina d3 e análogos da mesma para o tratamento de alopecia.
NZ714801A (en) 2013-05-29 2021-07-30 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1332841C (en) * 1984-11-27 1994-11-01 Noboru Kubodera Vitamin d derivatives and process for producing the same
JPS61267550A (ja) 1984-12-28 1986-11-27 Chugai Pharmaceut Co Ltd 9,10−セコ−5,7,10(19)−プレグナトリエン誘導体
JP3050564B2 (ja) * 1989-12-15 2000-06-12 中外製薬株式会社 新規な22―オキサビタミンd誘導体
GB9007236D0 (en) 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
JP2752506B2 (ja) * 1990-07-26 1998-05-18 株式会社クラレ 1α―ヒドロキシタキステロール誘導体の製造方法
DE4220757A1 (de) * 1992-06-24 1994-01-05 Schering Ag Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
GB9226877D0 (en) * 1992-12-23 1993-02-17 Leo Pharm Prod Ltd Chemical compounds
JP4089473B2 (ja) * 2003-03-12 2008-05-28 株式会社ジェイテクト ブラケット一体型リザーブタンク

Also Published As

Publication number Publication date
EP0755922A4 (de) 1997-07-02
KR970702245A (ko) 1997-05-13
CN1148380A (zh) 1997-04-23
ES2150560T3 (es) 2000-12-01
EP0755922A1 (de) 1997-01-29
AU2148295A (en) 1995-10-30
RU2142941C1 (ru) 1999-12-20
GR3034322T3 (en) 2000-12-29
DE69518410T2 (de) 2000-12-14
KR100244060B1 (ko) 2000-02-01
PT755922E (pt) 2000-11-30
DK0755922T3 (da) 2000-11-13
DE69518410D1 (de) 2000-09-21
CN1046502C (zh) 1999-11-17
US5824811A (en) 1998-10-20
EP0755922B1 (de) 2000-08-16
WO1995027697A1 (fr) 1995-10-19
BR9507355A (pt) 1997-09-09

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee