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ATE192192T1 - Stress-proteine epitopen - Google Patents

Stress-proteine epitopen

Info

Publication number
ATE192192T1
ATE192192T1 AT93918042T AT93918042T ATE192192T1 AT E192192 T1 ATE192192 T1 AT E192192T1 AT 93918042 T AT93918042 T AT 93918042T AT 93918042 T AT93918042 T AT 93918042T AT E192192 T1 ATE192192 T1 AT E192192T1
Authority
AT
Austria
Prior art keywords
purified
epitope
stress proteins
synthesised
substitution
Prior art date
Application number
AT93918042T
Other languages
English (en)
Inventor
James Peter Burnie
Ruth Christine Matthews
Original Assignee
Neutec Pharma Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neutec Pharma Plc filed Critical Neutec Pharma Plc
Application granted granted Critical
Publication of ATE192192T1 publication Critical patent/ATE192192T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT93918042T 1992-08-18 1993-08-17 Stress-proteine epitopen ATE192192T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9217542A GB2270076A (en) 1992-08-18 1992-08-18 Human HSP 90 Epitopes
PCT/GB1993/001745 WO1994004676A1 (en) 1992-08-18 1993-08-17 Stress protein epitopes

Publications (1)

Publication Number Publication Date
ATE192192T1 true ATE192192T1 (de) 2000-05-15

Family

ID=10720544

Family Applications (2)

Application Number Title Priority Date Filing Date
AT93918042T ATE192192T1 (de) 1992-08-18 1993-08-17 Stress-proteine epitopen
AT98102990T ATE280227T1 (de) 1992-08-18 1993-08-17 Epitope von stress proteinen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT98102990T ATE280227T1 (de) 1992-08-18 1993-08-17 Epitope von stress proteinen

Country Status (12)

Country Link
US (1) US5777083A (de)
EP (2) EP0656945B1 (de)
JP (1) JP3439213B2 (de)
AT (2) ATE192192T1 (de)
AU (1) AU4727593A (de)
DE (2) DE69333673T2 (de)
DK (2) DK0861892T3 (de)
ES (2) ES2231907T3 (de)
GB (1) GB2270076A (de)
GR (1) GR3033809T3 (de)
PT (2) PT656945E (de)
WO (1) WO1994004676A1 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750119A (en) * 1994-01-13 1998-05-12 Mount Sinai School Of Medicine Of The City University Of New York Immunotherapeutic stress protein-peptide complexes against cancer
US5997873A (en) 1994-01-13 1999-12-07 Mount Sinai School Of Medicine Of The City University Of New York Method of preparation of heat shock protein 70-peptide complexes
US5961979A (en) * 1994-03-16 1999-10-05 Mount Sinai School Of Medicine Of The City University Of New York Stress protein-peptide complexes as prophylactic and therapeutic vaccines against intracellular pathogens
EP0739981A1 (de) 1995-04-25 1996-10-30 Vrije Universiteit Brussel Variable Fragmente von Immunglobulinen-Verwendung zur therapeutischen oder veterinären Zwecken
US5837251A (en) * 1995-09-13 1998-11-17 Fordham University Compositions and methods using complexes of heat shock proteins and antigenic molecules for the treatment and prevention of neoplastic diseases
US5985270A (en) * 1995-09-13 1999-11-16 Fordham University Adoptive immunotherapy using macrophages sensitized with heat shock protein-epitope complexes
US5935576A (en) 1995-09-13 1999-08-10 Fordham University Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens
WO1997025999A1 (en) 1996-01-16 1997-07-24 Rensselaer Polytechnic Institute Peptides for altering osteoblast adhesion
US6017540A (en) 1997-02-07 2000-01-25 Fordham University Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes
US5830464A (en) 1997-02-07 1998-11-03 Fordham University Compositions and methods for the treatment and growth inhibition of cancer using heat shock/stress protein-peptide complexes in combination with adoptive immunotherapy
GB9710762D0 (en) 1997-05-23 1997-07-23 Cancer Res Inst Royal Binding complexes
US5948646A (en) 1997-12-11 1999-09-07 Fordham University Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes
WO1999042121A1 (en) 1998-02-20 1999-08-26 University Of Miami Modified heat shock protein-antigenic peptide complex
GB0008305D0 (en) * 2000-04-06 2000-05-24 Neutec Pharma Plc Treatment of fungal infections
AU6669401A (en) 2000-06-02 2001-12-11 Univ Connecticut Health Ct Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy
US7491702B2 (en) * 2001-04-18 2009-02-17 The Open University Polypeptides related to amyloid precursor protein, pharmaceutical compositions thereof, and methods of treatment using the same
US7622446B2 (en) * 2001-04-18 2009-11-24 The Open University Polypeptides, derivatives and uses thereof
US6916626B1 (en) * 2001-04-25 2005-07-12 Rockeby Biomed Ltd. Detection of Candida
WO2003015712A2 (en) 2001-08-20 2003-02-27 University Of Connecticut Health Center Methods for preparing compositions comprising heat shock proteins or alpha-2-macroglobulin
DE10161051B4 (de) * 2001-12-12 2005-09-15 Wieland, Heinrich, Prof. Dr. Diagnose der Malaria
US7959915B2 (en) 2003-03-12 2011-06-14 Tufts University Inhibitors of extracellular Hsp90
US7807378B2 (en) * 2005-12-29 2010-10-05 Industrial Technology Research Institute (Itri) Method of diagnosing myasthenia gravis and kits therefor
EP1806582B1 (de) * 2006-01-04 2011-05-11 Industrial Technology Research Institute Verfahren zur Diagnose von Myasthenia gravis
JP4283812B2 (ja) * 2006-01-06 2009-06-24 財団法人工業技術研究院 重症筋無力症の診断方法およびそのキット
WO2007098229A2 (en) * 2006-02-21 2007-08-30 Michigan State University Geldanamycin derivatives and method of use thereof
US20100113355A1 (en) 2007-04-27 2010-05-06 Naresh Chennamsetty Novel antibody molecules and nucleic acids binding to fungal stress protein hsp90
EP2257301B1 (de) 2008-03-03 2014-01-22 The University of Miami Auf allogenen krebszellen basierende immuntherapie
EP2274001A4 (de) 2008-03-20 2012-08-01 Univ Miami Impfung mit hitzeschockprotein gp96 und anwendungsverfahren dafür
EP3828201A1 (de) 2009-04-30 2021-06-02 Ablynx N.V. Verfahren zur herstellung von domänenantikörpern
KR20170109582A (ko) 2015-02-06 2017-09-29 히트 바이오로직스, 인코퍼레이티드 벡터 공동 발현 백신 및 공동 자극 분자
US11666649B2 (en) 2016-10-11 2023-06-06 University Of Miami Vectors and vaccine cells for immunity against Zika virus
WO2018187260A1 (en) 2017-04-04 2018-10-11 Heat Biologics, Inc. Intratumoral vaccination

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8915019D0 (en) * 1989-06-30 1989-08-23 Matthews Ruth C Medicaments
US5188964A (en) * 1990-04-12 1993-02-23 Board Of Regents, The University Of Texas System Method and kit for the prognostication of breast cancer patient via heat shock/stress protein determination
GB9016315D0 (en) * 1990-07-25 1990-09-12 Burnie James P Medicaments
DE4201181A1 (de) * 1992-01-17 1993-07-22 Boehringer Mannheim Gmbh Verfahren zur stabilisierung von proteinen

Also Published As

Publication number Publication date
EP0656945A1 (de) 1995-06-14
EP0861892A1 (de) 1998-09-02
ATE280227T1 (de) 2004-11-15
PT861892E (pt) 2005-03-31
EP0861892B1 (de) 2004-10-20
DK0656945T3 (da) 2000-09-11
ES2147560T3 (es) 2000-09-16
JPH08500016A (ja) 1996-01-09
JP3439213B2 (ja) 2003-08-25
DE69328489T2 (de) 2000-11-30
GB9217542D0 (en) 1992-09-30
GR3033809T3 (en) 2000-10-31
GB2270076A (en) 1994-03-02
WO1994004676A1 (en) 1994-03-03
PT656945E (pt) 2000-08-31
DE69328489D1 (de) 2000-05-31
US5777083A (en) 1998-07-07
ES2231907T3 (es) 2005-05-16
DE69333673D1 (de) 2004-11-25
DE69333673T2 (de) 2006-03-09
DK0861892T3 (da) 2005-02-14
EP0656945B1 (de) 2000-04-26
AU4727593A (en) 1994-03-15

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