ATE184050T1 - Verfahren zur herstellung th-unabhängiger zytotoxischer t-zymphozyten - Google Patents
Verfahren zur herstellung th-unabhängiger zytotoxischer t-zymphozytenInfo
- Publication number
- ATE184050T1 ATE184050T1 AT91918388T AT91918388T ATE184050T1 AT E184050 T1 ATE184050 T1 AT E184050T1 AT 91918388 T AT91918388 T AT 91918388T AT 91918388 T AT91918388 T AT 91918388T AT E184050 T1 ATE184050 T1 AT E184050T1
- Authority
- AT
- Austria
- Prior art keywords
- cymphocytes
- producing
- independent
- cytotoxic
- independent cytotoxic
- Prior art date
Links
- 231100000433 cytotoxic Toxicity 0.000 title 1
- 230000001472 cytotoxic effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 abstract 3
- 102000019223 Interleukin-1 receptor Human genes 0.000 abstract 1
- 108050006617 Interleukin-1 receptor Proteins 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 210000002443 helper t lymphocyte Anatomy 0.000 abstract 1
- 238000003259 recombinant expression Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/46—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58993990A | 1990-09-28 | 1990-09-28 | |
| US61416790A | 1990-11-09 | 1990-11-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE184050T1 true ATE184050T1 (de) | 1999-09-15 |
Family
ID=27080702
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91918388T ATE184050T1 (de) | 1990-09-28 | 1991-09-24 | Verfahren zur herstellung th-unabhängiger zytotoxischer t-zymphozyten |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0553186B1 (de) |
| JP (1) | JPH06503719A (de) |
| AT (1) | ATE184050T1 (de) |
| AU (1) | AU651397B2 (de) |
| CA (1) | CA2092548A1 (de) |
| DE (1) | DE69131577T2 (de) |
| DK (1) | DK0553186T3 (de) |
| ES (1) | ES2137933T3 (de) |
| GR (1) | GR3031964T3 (de) |
| WO (1) | WO1992005794A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2186685T3 (es) * | 1993-04-06 | 2003-05-16 | Targeted Genetics Corp | Genes hibridos destinados para ser utilizados en la produccion de celulas t citotoxicas independientes de celulas t auxiliares. |
| US5747292A (en) * | 1993-04-06 | 1998-05-05 | Fred Hutchinson Cancer Research Center | Chimeric cytokine receptors in lymphocytes |
| US5827642A (en) * | 1994-08-31 | 1998-10-27 | Fred Hutchinson Cancer Research Center | Rapid expansion method ("REM") for in vitro propagation of T lymphocytes |
| CA2198891A1 (en) * | 1994-08-31 | 1996-03-07 | Hartmut Wekerle | Genetically modified t cells |
| JP4767371B2 (ja) | 1996-01-17 | 2011-09-07 | インペリアル・イノベイションズ・リミテッド | 細胞障害性ｔリンパ球（ｃｔｌ）を用いた免疫療法 |
| ATE476496T1 (de) | 1996-03-04 | 2010-08-15 | Calyx Bio Ventures Inc | Modifizierte schnellvermehrungsmethode ('modified-rem') zur in vitro vermehrung von t-lymphozyten |
| AU726198B2 (en) * | 1996-03-04 | 2000-11-02 | Targeted Genetics Corporation | Modified rapid expansion methods ("modified-REM") for in vitro propagation of T lymphocytes |
| US6562345B1 (en) | 1996-11-12 | 2003-05-13 | City Of Hope | Immuno-reactive peptide CTL epitopes of human cytomegalovirus |
| US6156317A (en) * | 1996-11-12 | 2000-12-05 | City Of Hope | Immuno-reactive peptide CTL epitopes of human cytomegalovirus |
| US6074645A (en) | 1996-11-12 | 2000-06-13 | City Of Hope | Immuno-reactive peptide CTL epitopes of human cytomegalovirus |
| WO2002034769A2 (en) | 2000-10-20 | 2002-05-02 | City Of Hope | Immunoreactive peptide ctl epitopes of human cytomegalovirus pp150 |
| EP3568150A4 (de) * | 2017-01-10 | 2020-12-02 | Xcella Biosciences, Inc. | Kombinationstumorbehandlung mit integrin-bindendem fc-fusionsprotein und immunmodulator |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4968607A (en) * | 1987-11-25 | 1990-11-06 | Immunex Corporation | Interleukin-1 receptors |
| AU633287B2 (en) * | 1988-12-15 | 1993-01-28 | University Of Miami | Lymphokine saf |
| WO1991018982A1 (en) * | 1990-06-05 | 1991-12-12 | Immunex Corporation | Type ii interleukin-1 receptors |
-
1991
- 1991-09-24 AT AT91918388T patent/ATE184050T1/de not_active IP Right Cessation
- 1991-09-24 DK DK91918388T patent/DK0553186T3/da active
- 1991-09-24 EP EP91918388A patent/EP0553186B1/de not_active Expired - Lifetime
- 1991-09-24 AU AU88511/91A patent/AU651397B2/en not_active Ceased
- 1991-09-24 DE DE69131577T patent/DE69131577T2/de not_active Expired - Fee Related
- 1991-09-24 WO PCT/US1991/006921 patent/WO1992005794A1/en not_active Ceased
- 1991-09-24 CA CA002092548A patent/CA2092548A1/en not_active Abandoned
- 1991-09-24 ES ES91918388T patent/ES2137933T3/es not_active Expired - Lifetime
- 1991-09-24 JP JP3517906A patent/JPH06503719A/ja active Pending
-
1999
- 1999-11-25 GR GR990403057T patent/GR3031964T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69131577T2 (de) | 2000-05-04 |
| EP0553186A1 (de) | 1993-08-04 |
| EP0553186A4 (en) | 1994-06-08 |
| ES2137933T3 (es) | 2000-01-01 |
| WO1992005794A1 (en) | 1992-04-16 |
| GR3031964T3 (en) | 2000-03-31 |
| EP0553186B1 (de) | 1999-09-01 |
| DE69131577D1 (de) | 1999-10-07 |
| AU651397B2 (en) | 1994-07-21 |
| CA2092548A1 (en) | 1992-03-29 |
| AU8851191A (en) | 1992-04-28 |
| JPH06503719A (ja) | 1994-04-28 |
| DK0553186T3 (da) | 1999-11-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |