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ATE182899T1 - Gnrh analoge - Google Patents

Gnrh analoge

Info

Publication number
ATE182899T1
ATE182899T1 AT92908108T AT92908108T ATE182899T1 AT E182899 T1 ATE182899 T1 AT E182899T1 AT 92908108 T AT92908108 T AT 92908108T AT 92908108 T AT92908108 T AT 92908108T AT E182899 T1 ATE182899 T1 AT E182899T1
Authority
AT
Austria
Prior art keywords
unnatural amino
peptides
inhibit
synthesis
amino acid
Prior art date
Application number
AT92908108T
Other languages
English (en)
Inventor
Carl A Hoeger
Jean Edouard Frederic Rivier
Paula Guess Theobald
John S Porter
Catherine Laure Rivier
Wylie Walker Vale Jr
Original Assignee
Salk Inst For Biological Studi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Inst For Biological Studi filed Critical Salk Inst For Biological Studi
Application granted granted Critical
Publication of ATE182899T1 publication Critical patent/ATE182899T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Optical Radar Systems And Details Thereof (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Radar Systems Or Details Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT92908108T 1991-03-14 1992-03-11 Gnrh analoge ATE182899T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66969591A 1991-03-14 1991-03-14

Publications (1)

Publication Number Publication Date
ATE182899T1 true ATE182899T1 (de) 1999-08-15

Family

ID=24687346

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92908108T ATE182899T1 (de) 1991-03-14 1992-03-11 Gnrh analoge

Country Status (14)

Country Link
EP (1) EP0575490B1 (de)
JP (2) JP2522628B2 (de)
KR (1) KR0123009B1 (de)
AT (1) ATE182899T1 (de)
AU (1) AU664989B2 (de)
CA (1) CA2101316C (de)
DE (1) DE69229722T2 (de)
ES (1) ES2137945T3 (de)
IE (1) IE74226B1 (de)
IL (1) IL101074A (de)
NZ (1) NZ241755A (de)
PT (1) PT100246B (de)
WO (1) WO1992017025A2 (de)
ZA (1) ZA921559B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352796A (en) * 1989-10-30 1994-10-04 The Salk Institute For Biological Studies Amino acids useful in making GnRH analogs
US5413990A (en) * 1993-08-06 1995-05-09 Tap Pharmaceuticals Inc. N-terminus modified analogs of LHRH
US5502035A (en) * 1993-08-06 1996-03-26 Tap Holdings Inc. N-terminus modified analogs of LHRH
US5506207A (en) * 1994-03-18 1996-04-09 The Salk Institute For Biological Studies GNRH antagonists XIII
US5843901A (en) * 1995-06-07 1998-12-01 Advanced Research & Technology Institute LHRH antagonist peptides
DE19544212A1 (de) * 1995-11-28 1997-06-05 Asta Medica Ag Neue LH-RH-Antagonisten mit verbesserter Wirkung
WO1998027059A1 (fr) * 1996-12-18 1998-06-25 Meiji Seika Kaisha, Ltd. Nouveaux derives de la tetrahydrobenzindolone
US5821230A (en) * 1997-04-11 1998-10-13 Ferring Bv GnRH antagonist decapeptides
US5977302A (en) * 1997-11-20 1999-11-02 Ortho-Mcneil Pharmaceutical, Inc. Liquid phase process for the preparation of GnRH peptides
EP1268522B1 (de) 2000-03-14 2008-09-17 AEterna Zentaris GmbH Lh-rh-antagonisten, deren herstellung und verwendung als arzneimittel
AU2010330862B2 (en) 2009-12-18 2015-06-25 Idenix Pharmaceuticals, Inc. 5,5-fused arylene or heteroarylene hepatitis C virus inhibitors
ES2623979T3 (es) 2013-03-21 2017-07-12 Sanofi-Aventis Deutschland Gmbh Síntesis de productos peptídicos que contienen hidantoína
HUE033371T2 (en) 2013-03-21 2017-11-28 Sanofi Aventis Deutschland Process for the preparation of peptide products containing a ring imide
DE102015200585A1 (de) * 2015-01-15 2016-07-21 Sms Group Gmbh Verfahren und System zum Betrieb einer hüttentechnischen Anlage

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234571A (en) * 1979-06-11 1980-11-18 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
US4667014A (en) * 1983-03-07 1987-05-19 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists
US4677193A (en) * 1985-02-22 1987-06-30 The Salk Institute For Biological Studies Peptides containing an aliphatic-aromatic ketone side chain
US4801577A (en) * 1987-02-05 1989-01-31 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists
JPS63233963A (ja) * 1987-03-24 1988-09-29 Showa Denko Kk フエニルアラニン誘導体および蛋白分解酵素阻害剤
US5169932A (en) * 1989-10-30 1992-12-08 The Salk Institute For Biological Studies Gnrh analogs

Also Published As

Publication number Publication date
IL101074A (en) 1997-09-30
JP3222050B2 (ja) 2001-10-22
IL101074A0 (en) 1992-11-15
AU664989B2 (en) 1995-12-14
ZA921559B (en) 1992-11-25
CA2101316A1 (en) 1992-09-15
IE920825A1 (en) 1992-09-23
PT100246A (pt) 1993-07-30
ES2137945T3 (es) 2000-01-01
KR0123009B1 (ko) 1997-11-24
DE69229722D1 (de) 1999-09-09
WO1992017025A2 (en) 1992-10-01
AU1588292A (en) 1992-10-21
NZ241755A (en) 1993-06-25
EP0575490B1 (de) 1999-08-04
WO1992017025A3 (en) 1992-12-10
IE74226B1 (en) 1997-07-16
PT100246B (pt) 1999-06-30
DE69229722T2 (de) 2000-02-17
EP0575490A1 (de) 1993-12-29
JP2522628B2 (ja) 1996-08-07
JPH08277253A (ja) 1996-10-22
JPH06505751A (ja) 1994-06-30
CA2101316C (en) 2001-02-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee