ATE177419T1 - Asparaginsäure-derivate oder deren homologe und ihre verwendung zur behandlung neurologischer krankheiten - Google Patents
Asparaginsäure-derivate oder deren homologe und ihre verwendung zur behandlung neurologischer krankheitenInfo
- Publication number
- ATE177419T1 ATE177419T1 AT94308952T AT94308952T ATE177419T1 AT E177419 T1 ATE177419 T1 AT E177419T1 AT 94308952 T AT94308952 T AT 94308952T AT 94308952 T AT94308952 T AT 94308952T AT E177419 T1 ATE177419 T1 AT E177419T1
- Authority
- AT
- Austria
- Prior art keywords
- phenyl
- homologues
- treatment
- thienyl
- naphthyl
- Prior art date
Links
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 8
- 125000001624 naphthyl group Chemical group 0.000 abstract 6
- 125000001544 thienyl group Chemical group 0.000 abstract 6
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Otolaryngology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939324872A GB9324872D0 (en) | 1993-12-03 | 1993-12-03 | Pharmaceutical compounds |
US08/343,817 US5589501A (en) | 1993-12-03 | 1994-11-22 | Pharmaceutical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE177419T1 true ATE177419T1 (de) | 1999-03-15 |
Family
ID=26303963
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94308952T ATE177419T1 (de) | 1993-12-03 | 1994-12-02 | Asparaginsäure-derivate oder deren homologe und ihre verwendung zur behandlung neurologischer krankheiten |
Country Status (10)
Country | Link |
---|---|
US (2) | US5589501A (de) |
EP (1) | EP0656345B1 (de) |
JP (1) | JPH0820564A (de) |
AT (1) | ATE177419T1 (de) |
CA (1) | CA2137028A1 (de) |
DE (1) | DE69416945T2 (de) |
DK (1) | DK0656345T3 (de) |
ES (1) | ES2130370T3 (de) |
GB (1) | GB9324872D0 (de) |
GR (1) | GR3030102T3 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5576323A (en) * | 1993-12-03 | 1996-11-19 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
GB9617822D0 (en) * | 1996-08-27 | 1996-10-09 | Lilly Industries Ltd | Pharmaceutical compounds |
ES2133095B1 (es) * | 1997-03-25 | 2000-04-01 | Lilly Sa | Acidos alquilidenglutaminicos con propiedades farmaceuticas. |
DE19801646A1 (de) | 1998-01-17 | 1999-07-22 | Bayer Ag | Substituierte alpha,beta-annellierte Butyrolactone |
DE19801647A1 (de) | 1998-01-17 | 1999-07-22 | Bayer Ag | Substituierte beta,gamma-annellierte Lactone |
DE19801636A1 (de) | 1998-01-17 | 1999-07-22 | Bayer Ag | Substituierte bicyclische Lactone |
AU2001279313B2 (en) | 2000-08-04 | 2007-03-01 | Ampio Pharmaceuticals, Inc. | Method of using diketopiperazines and composition containing them |
CN102210852B (zh) * | 2003-05-15 | 2016-10-19 | 安皮奥制药股份有限公司 | T-细胞介导的疾病的治疗 |
EP2086924B1 (de) | 2006-11-01 | 2018-09-12 | Piramal Imaging SA | [f-18]markierte l-glutaminsäure, [f-18]markiertes l-glutamin, ihre derivate und ihre verwendung sowie verfahren zu ihrer herstellung |
EP2123621A1 (de) | 2008-05-20 | 2009-11-25 | Bayer Schering Pharma Aktiengesellschaft | Neue {F-18}-markierte L-Glutaminsäure- und L-Glutaminderivate (I), ihre Verwendung sowie Verfahren zu ihrer Herstellung |
EP2123620A1 (de) * | 2008-05-20 | 2009-11-25 | Bayer Schering Pharma Aktiengesellschaft | {F-19}-markierte L-Glutaminsäure und L-Glutaminderivat (III), Verwendung davon und Verfahren zu deren Erhalt |
EP2300011A4 (de) | 2008-05-27 | 2012-06-20 | Dmi Life Sciences Inc | Therapeutische verfahren und verbindungen |
EP2501416A1 (de) * | 2009-11-17 | 2012-09-26 | Piramal Imaging SA | Jodmarkierte homoglutaminsäure und glutaminsäurederivate |
WO2012033792A2 (en) | 2010-09-07 | 2012-03-15 | Dmi Acquisition Corp. | Treatment of diseases |
EP2520556A1 (de) * | 2011-05-03 | 2012-11-07 | Bayer Pharma Aktiengesellschaft | Radioaktiv markierte Aminosäuren zur diagnostischen Bildgebung |
MY172699A (en) | 2011-10-10 | 2019-12-10 | Ampio Pharmaceuticals Inc | Implantable medical devices with increased immune tolerance, and methods for making and implanting |
ES2795803T3 (es) | 2011-10-10 | 2020-11-24 | Ampio Pharmaceuticals Inc | Tratamiento de artropatía degenerativa |
JP6231484B2 (ja) | 2011-10-28 | 2017-11-15 | アンピオ ファーマシューティカルズ,インコーポレイテッド | 鼻炎の処置 |
CA2906864A1 (en) | 2013-03-15 | 2014-09-18 | Ampio Pharmaceuticals, Inc. | Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same |
KR20170045274A (ko) | 2014-08-18 | 2017-04-26 | 앰피오 파마슈티컬스 인코퍼레이티드 | 관절 징후의 치료 |
WO2016209969A1 (en) | 2015-06-22 | 2016-12-29 | Ampio Pharmaceuticals, Inc. | Use of low molecular weight fractions of human serum albumin in treating diseases |
-
1993
- 1993-12-03 GB GB939324872A patent/GB9324872D0/en active Pending
-
1994
- 1994-11-22 US US08/343,817 patent/US5589501A/en not_active Expired - Fee Related
- 1994-11-30 CA CA002137028A patent/CA2137028A1/en not_active Abandoned
- 1994-12-02 DK DK94308952T patent/DK0656345T3/da active
- 1994-12-02 JP JP6299206A patent/JPH0820564A/ja active Pending
- 1994-12-02 ES ES94308952T patent/ES2130370T3/es not_active Expired - Lifetime
- 1994-12-02 AT AT94308952T patent/ATE177419T1/de not_active IP Right Cessation
- 1994-12-02 EP EP94308952A patent/EP0656345B1/de not_active Expired - Lifetime
- 1994-12-02 DE DE69416945T patent/DE69416945T2/de not_active Expired - Fee Related
-
1996
- 1996-09-13 US US08/713,624 patent/US5739164A/en not_active Expired - Fee Related
-
1999
- 1999-04-30 GR GR990401184T patent/GR3030102T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0656345B1 (de) | 1999-03-10 |
EP0656345A1 (de) | 1995-06-07 |
GR3030102T3 (en) | 1999-07-30 |
DE69416945T2 (de) | 1999-08-12 |
DE69416945D1 (de) | 1999-04-15 |
ES2130370T3 (es) | 1999-07-01 |
GB9324872D0 (en) | 1994-01-19 |
CA2137028A1 (en) | 1995-06-04 |
US5589501A (en) | 1996-12-31 |
JPH0820564A (ja) | 1996-01-23 |
US5739164A (en) | 1998-04-14 |
DK0656345T3 (da) | 1999-09-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |