ATE175998T1 - Rekombinierte alkalische phosphatase aus kälberdarm - Google Patents
Rekombinierte alkalische phosphatase aus kälberdarmInfo
- Publication number
- ATE175998T1 ATE175998T1 AT93907388T AT93907388T ATE175998T1 AT E175998 T1 ATE175998 T1 AT E175998T1 AT 93907388 T AT93907388 T AT 93907388T AT 93907388 T AT93907388 T AT 93907388T AT E175998 T1 ATE175998 T1 AT E175998T1
- Authority
- AT
- Austria
- Prior art keywords
- alkaline phosphatase
- recombined
- calf
- interest
- calf intestinal
- Prior art date
Links
- 244000309466 calf Species 0.000 title abstract 3
- 102000002260 Alkaline Phosphatase Human genes 0.000 title 1
- 108020004774 Alkaline Phosphatase Proteins 0.000 title 1
- 102100024319 Intestinal-type alkaline phosphatase Human genes 0.000 abstract 2
- 101710184243 Intestinal-type alkaline phosphatase Proteins 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84921992A | 1992-03-10 | 1992-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE175998T1 true ATE175998T1 (de) | 1999-02-15 |
Family
ID=25305337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93907388T ATE175998T1 (de) | 1992-03-10 | 1993-03-10 | Rekombinierte alkalische phosphatase aus kälberdarm |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5707853A (de) |
| EP (2) | EP0867511A1 (de) |
| AT (1) | ATE175998T1 (de) |
| CA (1) | CA2102294A1 (de) |
| DE (1) | DE69323131T2 (de) |
| DK (1) | DK0584343T3 (de) |
| WO (1) | WO1993018139A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19819962A1 (de) | 1998-05-05 | 1999-11-11 | Roche Diagnostics Gmbh | Hochaktive alkalische Phosphatase |
| WO2002092020A2 (en) * | 2001-03-23 | 2002-11-21 | The Burnham Institute | Compositions and methods for modulating bone mineral deposition |
| US7888372B2 (en) * | 2001-03-23 | 2011-02-15 | National Institutes Of Health (Nih) | Compositions and methods for modulating bone mineral deposition |
| DE10213201A1 (de) * | 2002-03-25 | 2003-10-16 | Roche Diagnostics Gmbh | Erzeugung von schwach aktiven oder inaktiven Mutanten von Alkalischer Phosphatase und deren Expression in Hefe |
| CA2506738A1 (en) * | 2002-11-22 | 2004-06-10 | Wyeth | Composition for treating chlamydia infections and method for identifying same |
| US7319014B2 (en) * | 2003-02-24 | 2008-01-15 | New England Biolabs, Inc. | Overexpression, purification and characterization of a thermolabile phosphatase |
| ES2624905T3 (es) * | 2004-02-04 | 2017-07-18 | Am-Pharma B.V. | Uso de fosfatasa alcalina para la desintoxicación de LPS |
| US8129168B2 (en) * | 2009-01-14 | 2012-03-06 | Affymetrix, Inc. | Recombinant colwellia psychrerythraea alkaline phosphatase and uses thereof |
| EP3425048A1 (de) | 2014-01-24 | 2019-01-09 | AM-Pharma B.V. | Chimäre alkalische phosphataseartige proteine |
| PT3461891T (pt) | 2014-01-24 | 2020-07-30 | Am Pharma Bv | Processamento a jusante de uma fosfatase alcalina |
| CN105802979B (zh) * | 2016-04-01 | 2019-09-06 | 郑州科蒂亚生物技术有限公司 | 一种小牛肠碱性磷酸酶的表达载体及表达方法 |
| WO2018089799A1 (en) * | 2016-11-11 | 2018-05-17 | Dnalite Therapeutics, Inc. | Structures and methods for gene therapy |
| CA3057089A1 (en) * | 2017-03-21 | 2018-09-27 | Synthetic Biologics, Inc. | Alkaline phosphatase formulations |
| WO2019069977A1 (ja) | 2017-10-03 | 2019-04-11 | キッコーマン株式会社 | アルカリホスファターゼの製造方法及びそれを用いて得られるアルカリホスファターゼ、並びにその製造のためのベクター及び形質転換体 |
| US11338020B2 (en) | 2018-01-09 | 2022-05-24 | Synthetic Biologics, Inc. | Alkaline phosphatase agents for treatment of neurodevelopmental disorders |
| US11654184B2 (en) | 2018-03-20 | 2023-05-23 | Theriva Biologics, Inc. | Alkaline phosphatase agents for treatment of radiation disorders |
| CA3094173A1 (en) | 2018-03-20 | 2019-09-26 | Synthetic Biologics, Inc. | Intestinal alkaline phosphatase formulations |
| EP3807408A4 (de) * | 2018-06-18 | 2022-03-30 | Synthetic Biologics, Inc. | Verfahren zur herstellung von alkalischen phosphatasemitteln |
| CN112752842B (zh) * | 2018-09-25 | 2024-08-20 | 东丽株式会社 | 碱性磷酸酶组合物以及去磷酸化核酸和标记化核酸的制造方法 |
| CN113993541A (zh) | 2019-05-06 | 2022-01-28 | 合成生物制品有限公司 | 基于碱性磷酸酶的肿瘤学治疗 |
| JP7510787B2 (ja) | 2020-05-28 | 2024-07-04 | シスメックス株式会社 | アルカリフォスファターゼ融合抗体及びその製造方法、並びに免疫測定用試薬及び免疫測定方法 |
| CN113621079B (zh) * | 2021-09-07 | 2023-04-11 | 金标优尼科(无锡)生物科技有限公司 | Fab抗体与小牛肠碱性磷酸酶的融合蛋白及其制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE298424C (de) * | ||||
| DD246686A (de) * | ||||
| DE246686C (de) * | ||||
| DE159993C (de) * | ||||
| DD159993B1 (de) * | 1981-06-29 | 1987-05-13 | Anton Horn | Immunosorbentchromatographische reinigung von alkalischer phosphatase aus kaelberdarm |
| US5084379A (en) * | 1983-04-29 | 1992-01-28 | Biowhittaker, Inc. | Fluorometric assay of chymopapain hypersensitivity and reagents therefor |
| US4707438A (en) * | 1984-08-22 | 1987-11-17 | Tel Aviv University | Immunoassay for breast cancer employing monoclonal antibodies |
| FI71433C (fi) * | 1985-05-14 | 1986-12-19 | Orion Yhtymae Oy | Apparat foer immunokemisk bestaemning |
| US4885166A (en) * | 1985-06-11 | 1989-12-05 | Ciba-Geigy Corporation | Hybrid interferons |
| JP2564540B2 (ja) * | 1987-04-01 | 1996-12-18 | 株式会社日立製作所 | 免疫分析方法 |
| US5204244A (en) * | 1987-10-27 | 1993-04-20 | Oncogen | Production of chimeric antibodies by homologous recombination |
| GB8800078D0 (en) * | 1988-01-05 | 1988-02-10 | Ciba Geigy Ag | Novel antibodies |
| US5089424A (en) * | 1988-06-14 | 1992-02-18 | Abbott Laboratories | Method and apparatus for heterogeneous chemiluminescence assay |
| US5079171A (en) * | 1988-09-15 | 1992-01-07 | Adeza Biomedical Corporation | Determining pregnancy induced hypertension and eclampsia by immunoassay of cellular fibronectin |
| US5079170A (en) * | 1989-05-18 | 1992-01-07 | Quidel Corporation | Method of sample transfer using a filter applicator |
| DD298424A5 (de) * | 1989-11-22 | 1992-02-20 | Universitaet Leipzig,De | Verfahren zur gewinnung von alkalischer phosphatase aus kaelberdarm |
-
1993
- 1993-03-10 DK DK93907388T patent/DK0584343T3/da active
- 1993-03-10 CA CA002102294A patent/CA2102294A1/en not_active Abandoned
- 1993-03-10 DE DE69323131T patent/DE69323131T2/de not_active Expired - Fee Related
- 1993-03-10 EP EP98250084A patent/EP0867511A1/de not_active Withdrawn
- 1993-03-10 EP EP93907388A patent/EP0584343B1/de not_active Expired - Lifetime
- 1993-03-10 WO PCT/US1993/002172 patent/WO1993018139A1/en active IP Right Grant
- 1993-03-10 AT AT93907388T patent/ATE175998T1/de active
-
1995
- 1995-01-03 US US08/368,071 patent/US5707853A/en not_active Expired - Fee Related
- 1995-06-02 US US08/458,181 patent/US5773226A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0584343A1 (de) | 1994-03-02 |
| EP0584343A4 (en) | 1996-03-20 |
| DE69323131D1 (de) | 1999-03-04 |
| EP0584343B1 (de) | 1999-01-20 |
| US5707853A (en) | 1998-01-13 |
| DK0584343T3 (da) | 1999-09-13 |
| EP0867511A1 (de) | 1998-09-30 |
| DE69323131T2 (de) | 1999-09-16 |
| CA2102294A1 (en) | 1993-09-11 |
| WO1993018139A1 (en) | 1993-09-16 |
| US5773226A (en) | 1998-06-30 |
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