[go: up one dir, main page]

ATE168719T1 - Osteogene peptide - Google Patents

Osteogene peptide

Info

Publication number
ATE168719T1
ATE168719T1 AT91919612T AT91919612T ATE168719T1 AT E168719 T1 ATE168719 T1 AT E168719T1 AT 91919612 T AT91919612 T AT 91919612T AT 91919612 T AT91919612 T AT 91919612T AT E168719 T1 ATE168719 T1 AT E168719T1
Authority
AT
Austria
Prior art keywords
osteogenic
methods
proteins
polypeptide chains
osteogenic devices
Prior art date
Application number
AT91919612T
Other languages
English (en)
Inventor
Hermann Oppermann
Engin Ozkaynak
David C Reuger
Thangavel Kuberasampath
Original Assignee
Stryker Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stryker Corp filed Critical Stryker Corp
Application granted granted Critical
Publication of ATE168719T1 publication Critical patent/ATE168719T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biophysics (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT91919612T 1990-10-18 1991-10-18 Osteogene peptide ATE168719T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59954390A 1990-10-18 1990-10-18

Publications (1)

Publication Number Publication Date
ATE168719T1 true ATE168719T1 (de) 1998-08-15

Family

ID=24400058

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91919612T ATE168719T1 (de) 1990-10-18 1991-10-18 Osteogene peptide

Country Status (9)

Country Link
EP (1) EP0643767B1 (de)
JP (2) JPH07500487A (de)
AT (1) ATE168719T1 (de)
AU (1) AU663689B2 (de)
CA (1) CA2094027C (de)
DE (1) DE69129865T2 (de)
DK (1) DK0643767T3 (de)
ES (1) ES2120964T3 (de)
WO (1) WO1992007073A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6150328A (en) 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
US5688678A (en) * 1990-05-16 1997-11-18 Genetics Institute, Inc. DNA encoding and methods for producing BMP-8 proteins
US7378392B1 (en) 1990-05-16 2008-05-27 Genetics Institute, Llc Bone and cartilage inductive proteins
ATE209251T1 (de) * 1990-05-16 2001-12-15 Genetics Inst Knochen- und knorpel-bildung hervorrufende proteine
US5652118A (en) * 1991-03-11 1997-07-29 Creative Biomolecules, Inc. Nucleic acid encoding a novel morphogenic protein, OP-3
US6194376B1 (en) 1991-03-11 2001-02-27 Creative Biomolecules, Inc. Method for modulating inflammatory response comprising administering morphogen
US6090776A (en) * 1991-03-11 2000-07-18 Creative Bio Molecules, Inc. Morphogen treatment of organ implants
US6077823A (en) * 1991-03-11 2000-06-20 Creative Biomolecules, Inc. Method for reducing tissue damage associated with ischemia-reperfusion or hypoxia injury
US6395883B1 (en) 1991-03-11 2002-05-28 Curis, Inc. Soluble morphogenic protein complex compositions of matter
US6399569B1 (en) 1991-03-11 2002-06-04 Curis, Inc. Morphogen treatments for limiting proliferation of epithelial cells
WO1993000432A1 (en) * 1991-06-25 1993-01-07 Genetics Institute, Inc. Bmp-9 compositions
US6287816B1 (en) 1991-06-25 2001-09-11 Genetics Institute, Inc. BMP-9 compositions
JP3693338B2 (ja) * 1991-08-30 2005-09-07 キュリス インコーポレイテッド 組織形成因子誘導による炎症反応の調節
EP0652953B1 (de) * 1992-07-31 2005-01-26 Stryker Corporation Löslicher komplex morphogener proteine und zusammensetzungen davon
EP0690871A4 (de) * 1993-01-12 1999-10-20 Univ Johns Hopkins Med Wachstums-differenzierungsfaktor-5
EP0717633A4 (de) * 1993-07-09 1998-05-20 Univ Johns Hopkins Med Wachstums-differenzierungsfaktor-7
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
DE69434651T2 (de) 1993-12-07 2007-03-08 Genetics Institute, Inc., Cambridge Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen
US6040431A (en) * 1995-06-07 2000-03-21 Stryker Corporation Single chain analogs of the TGF-β superfamily (morphons)
AU709991B2 (en) * 1995-08-14 1999-09-09 Creative Biomolecules, Inc. Binding of osteogenic protein-1 (OP-1) and analogs thereof to the cell surface receptor ALK-1 and analogs thereof
ATE364629T1 (de) 1996-01-22 2007-07-15 Curis Inc Methoden zur herstellung von op-1 morphogen analoge
JP4847634B2 (ja) 1996-03-22 2011-12-28 ストライカー・コーポレーション 中枢神経系の虚血または外傷の機能的回復を増大させる方法
US6034062A (en) * 1997-03-13 2000-03-07 Genetics Institute, Inc. Bone morphogenetic protein (BMP)-9 compositions and their uses
US6727224B1 (en) 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
DE19906096A1 (de) 1999-02-13 2000-08-17 Walter Sebald Protein mit einem Heparin-bindenden Epitop
PT1223990E (pt) 1999-10-15 2004-12-31 Fidia Advanced Biopolymers Srl Formulacoes de acido hialuronico para administracao de proteinas osteogenicas
WO2001068817A1 (fr) * 2000-03-16 2001-09-20 Kyowa Hakko Kogyo Co., Ltd. Facteur de reparation du rein
EP1399023B1 (de) 2001-06-01 2008-04-30 Wyeth Zusammensetzungen für die systemische verabreichung von sequenzen, die für knochenmorphogenese-proteinen kodieren
ATE303169T1 (de) 2001-11-19 2005-09-15 Scil Technology Gmbh Homogen beschichtete vorrichtung mit osteoinduktiven und osteokonduktiven eigenschaften
ATE322916T1 (de) 2002-09-10 2006-04-15 Scil Technology Gmbh Unter verringerter sauerstoffkonzentration mit einem osteoinduktiven protein beschichtetes metallimplantat
DE602005022998D1 (de) 2004-03-10 2010-09-30 Scil Technology Gmbh Überzogene implantate, ihre herstellung und verwendung davon
EP2186823A1 (de) * 2005-11-14 2010-05-19 Merial Limited Gentherapie für Nierenversagen
WO2023272658A1 (zh) * 2021-06-30 2023-01-05 北京泽勤生物医药有限公司 增强成骨细胞活性的多肽及其在治疗骨科疾病中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU628050B2 (en) * 1988-04-08 1992-09-10 Stryker Corporation Biosynthetic osteogenic proteins and osteogenic devices containing them
CA2030518C (en) * 1989-03-28 2000-03-21 Elizabeth A. Wang Osteoinductive compositions

Also Published As

Publication number Publication date
DE69129865T2 (de) 1999-03-04
EP0643767A1 (de) 1995-03-22
JPH11262395A (ja) 1999-09-28
JPH07500487A (ja) 1995-01-19
CA2094027C (en) 2001-12-25
DE69129865D1 (de) 1998-08-27
AU8900091A (en) 1992-05-20
WO1992007073A1 (en) 1992-04-30
CA2094027A1 (en) 1992-04-19
ES2120964T3 (es) 1998-11-16
EP0643767B1 (de) 1998-07-22
DK0643767T3 (da) 1999-04-26
AU663689B2 (en) 1995-10-19

Similar Documents

Publication Publication Date Title
ATE168719T1 (de) Osteogene peptide
DE68925773D1 (de) Osteogene vorrichtungen
ATE167486T1 (de) Osteogene vorrichtungen
ATE118015T1 (de) Biologisch aktive polypeptide, die auf transformierten wachstumsfaktor-beta-sequenzen basieren.
DE3856265D1 (de) Varianten des pankreatischen Rinder-Trypsininhibitors, deren Herstellung und Verwendung
DE69939330D1 (de) Wachstumsfaktor-homologe zvegf-3
NO992158L (no) Nukleinsyre- og aminosyresekvenser forbundet med Heliobacter Pylori og vaksinepreparater av disse.
ATE166231T1 (de) Produktion und verwendung von antihelmintischen substanzen und schützenden immunogenen
ES2044928T3 (es) Enzima alfa-amidante en terminal c y procedimiento para la produccion y el uso del mismo.
DE59109235D1 (de) Peptide des HIV-gag Proteins, ihre Herstellung und Verwendung
DE3873273D1 (de) Verfahren zur selektiven spaltung von fusionsproteinen.
ATE116333T1 (de) Biologisch aktive moleküle.
DE69534738D1 (de) Leukocyten-aktivierender Faktor
DE69613086D1 (de) Antigenen Peptide mit Glycinsubstitution
DK0540560T3 (da) Ancrod-lignende proteiner, fremstilling og anvendelse deraf
DE3876240D1 (de)
DE60138885D1 (de) Polypeptide mit aktivität der stimulierung von neutrophilen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee