ATE159018T1 - Pyrrolo(2,3-d>azepinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen - Google Patents
Pyrrolo(2,3-d>azepinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungenInfo
- Publication number
- ATE159018T1 ATE159018T1 AT91310903T AT91310903T ATE159018T1 AT E159018 T1 ATE159018 T1 AT E159018T1 AT 91310903 T AT91310903 T AT 91310903T AT 91310903 T AT91310903 T AT 91310903T AT E159018 T1 ATE159018 T1 AT E159018T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrrolo
- production
- pharmaceutical preparations
- preparations containing
- containing same
- Prior art date
Links
- 150000001538 azepines Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 phenylsulphonyl Chemical group 0.000 abstract 2
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000499 benzofuranyl group Chemical group O1C(=CC2=C1C=CC=C2)* 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 125000000723 dihydrobenzofuranyl group Chemical group O1C(CC2=C1C=CC=C2)* 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909025890A GB9025890D0 (en) | 1990-11-28 | 1990-11-28 | Pharmaceutical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE159018T1 true ATE159018T1 (de) | 1997-10-15 |
Family
ID=10686134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91310903T ATE159018T1 (de) | 1990-11-28 | 1991-11-27 | Pyrrolo(2,3-d>azepinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5258378A (de) |
| EP (1) | EP0488663B1 (de) |
| JP (1) | JPH04266888A (de) |
| AT (1) | ATE159018T1 (de) |
| CA (1) | CA2056144A1 (de) |
| DE (1) | DE69127880D1 (de) |
| GB (1) | GB9025890D0 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5616575A (en) * | 1995-12-04 | 1997-04-01 | Regents Of The University Of Minnesota | Bioactive tricyclic ibogaine analogs |
| US6410527B1 (en) * | 1998-03-02 | 2002-06-25 | Schering Corporation | Method of treating obsessive compulsive disorders, somatoform disorders, dissociative disorders, eating disorders, impulse control disorders, and autism |
| EP1778243B1 (de) * | 2004-06-30 | 2012-10-31 | Athersys, Inc. | Substituierte azepinderivate als serotoninrezeptor-modulatoren |
| US7893051B2 (en) * | 2006-01-19 | 2011-02-22 | Athersys, Inc. | Thiophenyl and pyrrolyl azepines as serotonin 5-HT2c receptor ligands and uses thereof |
| BR112015014674A2 (pt) | 2012-12-21 | 2017-07-11 | Abt Holding Co | benzazepinas como ligantes do receptor de serotonina 5-ht2c e usos das mesmas |
| WO2014159067A1 (en) | 2013-03-13 | 2014-10-02 | Abt Holding Company | Thienylindole azepines as serotonin 5-ht2c receptor ligands and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3553232A (en) * | 1967-08-25 | 1971-01-05 | Upjohn Co | 4-(1,4,5,6-tetrahydroazepine(4,5-b)indole-3(2h)-yl)butyrophenones |
| DE3070467D1 (en) * | 1979-11-02 | 1985-05-15 | Sandoz Ag | Azepinoindoles, process for their production and pharmaceutical compositions containing them |
| ZA821020B (en) * | 1981-02-18 | 1983-10-26 | Thomae Gmbh Dr K | Azepine derivatives, process for their preparation and pharmaceutical compositions thereof |
| DE3230696A1 (de) * | 1982-08-18 | 1984-02-23 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue thieno-thiazol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DK180485D0 (da) * | 1985-04-22 | 1985-04-23 | Novo Industri As | Nitrogenholdige forbindelser |
| GB8800891D0 (en) * | 1988-01-15 | 1988-02-17 | Lilly Industries Ltd | Pharmaceutical compounds |
| GB8909132D0 (en) * | 1989-04-21 | 1989-06-07 | Lilly Industries Ltd | Pharmaceutical compounds |
-
1990
- 1990-11-28 GB GB909025890A patent/GB9025890D0/en active Pending
-
1991
- 1991-11-19 US US07/794,283 patent/US5258378A/en not_active Expired - Fee Related
- 1991-11-25 CA CA002056144A patent/CA2056144A1/en not_active Abandoned
- 1991-11-27 DE DE69127880T patent/DE69127880D1/de not_active Expired - Lifetime
- 1991-11-27 JP JP3311240A patent/JPH04266888A/ja active Pending
- 1991-11-27 EP EP91310903A patent/EP0488663B1/de not_active Expired - Lifetime
- 1991-11-27 AT AT91310903T patent/ATE159018T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GB9025890D0 (en) | 1991-01-09 |
| JPH04266888A (ja) | 1992-09-22 |
| CA2056144A1 (en) | 1992-05-29 |
| DE69127880D1 (de) | 1997-11-13 |
| US5258378A (en) | 1993-11-02 |
| EP0488663B1 (de) | 1997-10-08 |
| EP0488663A1 (de) | 1992-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |