ATE147432T1 - Polynucleotidsequenzen, die für den humanen fc- rezeptor für immunoglobulin codieren - Google Patents
Polynucleotidsequenzen, die für den humanen fc- rezeptor für immunoglobulin codierenInfo
- Publication number
- ATE147432T1 ATE147432T1 AT87903479T AT87903479T ATE147432T1 AT E147432 T1 ATE147432 T1 AT E147432T1 AT 87903479 T AT87903479 T AT 87903479T AT 87903479 T AT87903479 T AT 87903479T AT E147432 T1 ATE147432 T1 AT E147432T1
- Authority
- AT
- Austria
- Prior art keywords
- receptor
- immunoglobulin
- human
- polynucleotide sequences
- sequences coding
- Prior art date
Links
- 108060003951 Immunoglobulin Proteins 0.000 title abstract 3
- 102000018358 immunoglobulin Human genes 0.000 title abstract 3
- 102000009109 Fc receptors Human genes 0.000 title 1
- 108010087819 Fc receptors Proteins 0.000 title 1
- 102000040430 polynucleotide Human genes 0.000 title 1
- 108091033319 polynucleotide Proteins 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 title 1
- 230000004988 N-glycosylation Effects 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000002299 complementary DNA Substances 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 210000005260 human cell Anatomy 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPH616686 | 1986-05-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE147432T1 true ATE147432T1 (de) | 1997-01-15 |
Family
ID=3771638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87903479T ATE147432T1 (de) | 1986-05-29 | 1987-05-29 | Polynucleotidsequenzen, die für den humanen fc- rezeptor für immunoglobulin codieren |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0268636B1 (de) |
| JP (1) | JP2713410B2 (de) |
| AT (1) | ATE147432T1 (de) |
| AU (1) | AU595623B2 (de) |
| CA (1) | CA1340935C (de) |
| DE (1) | DE3751996T2 (de) |
| HK (1) | HK1006977A1 (de) |
| NZ (1) | NZ220504A (de) |
| WO (1) | WO1987007277A1 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5985599A (en) * | 1986-05-29 | 1999-11-16 | The Austin Research Institute | FC receptor for immunoglobulin |
| AU3284289A (en) * | 1987-12-04 | 1989-07-05 | Schering Biotech Corporation | Human fc-gamma receptor |
| US5767077A (en) * | 1988-05-27 | 1998-06-16 | Applied Research Systems Ars Holding N.V. | Human Fc-γ receptor III |
| AU3740089A (en) * | 1988-05-27 | 1989-12-12 | Schering Biotech Corporation | Human fc-gamma receptor iii |
| WO1991006570A1 (en) * | 1989-10-25 | 1991-05-16 | The University Of Melbourne | HYBRID Fc RECEPTOR MOLECULES |
| US7317091B2 (en) | 2002-03-01 | 2008-01-08 | Xencor, Inc. | Optimized Fc variants |
| US8188231B2 (en) | 2002-09-27 | 2012-05-29 | Xencor, Inc. | Optimized FC variants |
| US20040132101A1 (en) | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
| US7662925B2 (en) | 2002-03-01 | 2010-02-16 | Xencor, Inc. | Optimized Fc variants and methods for their generation |
| US8084582B2 (en) | 2003-03-03 | 2011-12-27 | Xencor, Inc. | Optimized anti-CD20 monoclonal antibodies having Fc variants |
| US8388955B2 (en) | 2003-03-03 | 2013-03-05 | Xencor, Inc. | Fc variants |
| US20090010920A1 (en) | 2003-03-03 | 2009-01-08 | Xencor, Inc. | Fc Variants Having Decreased Affinity for FcyRIIb |
| US9051373B2 (en) | 2003-05-02 | 2015-06-09 | Xencor, Inc. | Optimized Fc variants |
| US8101720B2 (en) | 2004-10-21 | 2012-01-24 | Xencor, Inc. | Immunoglobulin insertions, deletions and substitutions |
| US9714282B2 (en) | 2003-09-26 | 2017-07-25 | Xencor, Inc. | Optimized Fc variants and methods for their generation |
| AU2005227326B2 (en) | 2004-03-24 | 2009-12-03 | Xencor, Inc. | Immunoglobulin variants outside the Fc region |
| US20150010550A1 (en) | 2004-07-15 | 2015-01-08 | Xencor, Inc. | OPTIMIZED Fc VARIANTS |
| EP2314618A3 (de) | 2004-11-12 | 2011-10-19 | Xencor Inc. | Fc-Varianten mit modifizierter Bindung an FcRn |
| US8802820B2 (en) | 2004-11-12 | 2014-08-12 | Xencor, Inc. | Fc variants with altered binding to FcRn |
| US8367805B2 (en) | 2004-11-12 | 2013-02-05 | Xencor, Inc. | Fc variants with altered binding to FcRn |
| US8546543B2 (en) | 2004-11-12 | 2013-10-01 | Xencor, Inc. | Fc variants that extend antibody half-life |
| WO2007041635A2 (en) | 2005-10-03 | 2007-04-12 | Xencor, Inc. | Fc variants with optimized fc receptor binding properties |
| AU2006302254B2 (en) | 2005-10-06 | 2011-05-26 | Xencor, Inc. | Optimized anti-CD30 antibodies |
| US8524867B2 (en) | 2006-08-14 | 2013-09-03 | Xencor, Inc. | Optimized antibodies that target CD19 |
| JP5562031B2 (ja) | 2006-09-18 | 2014-07-30 | ゼンコー・インコーポレイテッド | Ｈｍ１．２４を標的とする最適化抗体 |
| EP2235059B1 (de) | 2007-12-26 | 2015-02-18 | Xencor, Inc. | Fc-varianten mit modifizierter bindung an fcrn |
| US9493578B2 (en) | 2009-09-02 | 2016-11-15 | Xencor, Inc. | Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens |
| US8362210B2 (en) | 2010-01-19 | 2013-01-29 | Xencor, Inc. | Antibody variants with enhanced complement activity |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE451596B (sv) * | 1983-06-22 | 1987-10-19 | Excorim Kb | Forfarande for utvinning av protein g |
-
1987
- 1987-05-29 AT AT87903479T patent/ATE147432T1/de not_active IP Right Cessation
- 1987-05-29 DE DE3751996T patent/DE3751996T2/de not_active Expired - Lifetime
- 1987-05-29 WO PCT/AU1987/000159 patent/WO1987007277A1/en active IP Right Grant
- 1987-05-29 AU AU74881/87A patent/AU595623B2/en not_active Expired
- 1987-05-29 JP JP62503462A patent/JP2713410B2/ja not_active Expired - Lifetime
- 1987-05-29 NZ NZ220504A patent/NZ220504A/xx unknown
- 1987-05-29 HK HK98106183A patent/HK1006977A1/en not_active IP Right Cessation
- 1987-05-29 EP EP87903479A patent/EP0268636B1/de not_active Expired - Lifetime
- 1987-05-29 CA CA000538363A patent/CA1340935C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2713410B2 (ja) | 1998-02-16 |
| AU595623B2 (en) | 1990-04-05 |
| JPS63503386A (ja) | 1988-12-08 |
| HK1006977A1 (en) | 1999-03-26 |
| DE3751996T2 (de) | 1997-07-03 |
| NZ220504A (en) | 1991-09-25 |
| EP0268636A1 (de) | 1988-06-01 |
| DE3751996D1 (de) | 1997-02-20 |
| CA1340935C (en) | 2000-03-28 |
| EP0268636B1 (de) | 1997-01-08 |
| WO1987007277A1 (en) | 1987-12-03 |
| EP0268636A4 (de) | 1988-09-28 |
| AU7488187A (en) | 1987-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |