ATE132164T1 - Verfahren zur steigerung und zur hemmung der wirkung eines insulinähnlichen wachstumfaktors - Google Patents
Verfahren zur steigerung und zur hemmung der wirkung eines insulinähnlichen wachstumfaktorsInfo
- Publication number
- ATE132164T1 ATE132164T1 AT88905539T AT88905539T ATE132164T1 AT E132164 T1 ATE132164 T1 AT E132164T1 AT 88905539 T AT88905539 T AT 88905539T AT 88905539 T AT88905539 T AT 88905539T AT E132164 T1 ATE132164 T1 AT E132164T1
- Authority
- AT
- Austria
- Prior art keywords
- insulin
- growth factor
- inhibiting
- increase
- effect
- Prior art date
Links
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 title abstract 2
- 230000002401 inhibitory effect Effects 0.000 title abstract 2
- 102000013275 Somatomedins Human genes 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 102000031991 insulin-like growth factor II binding proteins Human genes 0.000 abstract 1
- 108091010172 insulin-like growth factor II binding proteins Proteins 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4743—Insulin-like growth factor binding protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Polymerisation Methods In General (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18075988A | 1988-04-12 | 1988-04-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE132164T1 true ATE132164T1 (de) | 1996-01-15 |
Family
ID=22661666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88905539T ATE132164T1 (de) | 1988-04-12 | 1988-06-03 | Verfahren zur steigerung und zur hemmung der wirkung eines insulinähnlichen wachstumfaktors |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0418230B1 (de) |
| JP (1) | JPH03504597A (de) |
| AT (1) | ATE132164T1 (de) |
| AU (1) | AU1955388A (de) |
| BR (1) | BR8901711A (de) |
| DE (1) | DE3854842T2 (de) |
| WO (1) | WO1989009792A1 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5258287A (en) * | 1988-03-22 | 1993-11-02 | Genentech, Inc. | DNA encoding and methods of production of insulin-like growth factor binding protein BP53 |
| WO1990000569A1 (en) * | 1988-07-15 | 1990-01-25 | Central Sydney Area Health Service | Acid-labile subunit (als) of insulin-like-growth factor (igf) binding protein complex |
| US6465423B1 (en) | 1988-07-15 | 2002-10-15 | Central Sydney Area Health Service | Acid-labile subunit (ALS) of insulin-like growth factor binding protein complex |
| US5324820A (en) * | 1988-07-15 | 1994-06-28 | Central Sydney Area Health Service | Acid-labile subunit (ALS) of insulin-like growth factor binding protein complex |
| GB8826451D0 (en) * | 1988-11-11 | 1988-12-14 | Sandoz Ltd | Improvements in/relating to organic compounds |
| IL92816A0 (en) * | 1988-12-22 | 1990-09-17 | Biogrowth Inc | Recombinant dna molecules,hosts,processes and human somatomedin carrier protein-like polypeptides |
| US5126324A (en) * | 1990-06-07 | 1992-06-30 | Genentech, Inc. | Method of enhancing growth in patients using combination therapy |
| CA2090703A1 (en) * | 1990-08-28 | 1992-03-01 | Michael C. Kiefer | Insulin-like growth factor binding protein (igfbp-4) |
| US5212074A (en) * | 1990-08-28 | 1993-05-18 | Chiron Corporation | Genetic material encoding new insulin-like growth factor binding protein igfbp-6 |
| US6326154B1 (en) | 1990-11-19 | 2001-12-04 | Genentech, Inc. | Ligand-mediated immunofunctional hormone binding protein assay method |
| US5210017A (en) * | 1990-11-19 | 1993-05-11 | Genentech, Inc. | Ligand-mediated immunofunctional hormone binding protein assay method |
| ATE247164T1 (de) * | 1991-01-08 | 2003-08-15 | Chiron Corp | Insulinartigen wachstumsfaktor bindendes protein |
| US5187151A (en) * | 1991-02-12 | 1993-02-16 | Genentech, Inc. | Use of binding protein with igf-i as an anabolic growth promoting agent |
| CA2148685A1 (en) | 1992-11-04 | 1994-05-11 | Dennis L. Andress | Truncated insulin-like growth factor binding proteins having mitogenic activity |
| US6124259A (en) * | 1993-01-28 | 2000-09-26 | Celtrix Pharmaceuticals, Inc. | Method for treating ophthalmic disorders with IGFBP |
| AU6626794A (en) * | 1993-04-07 | 1994-10-24 | Amgen Boulder Inc. | Methods of using insulin-like growth factor binding proteins |
| US6121416A (en) | 1997-04-04 | 2000-09-19 | Genentech, Inc. | Insulin-like growth factor agonist molecules |
| US6420518B1 (en) | 1997-04-04 | 2002-07-16 | Genetech, Inc. | Insulin-like growth factor agonist molecules |
| PT1141014E (pt) | 1999-01-06 | 2005-04-29 | Genentech Inc | Variante mutante do factor de crescimento semelhante a insulina (igf-i) |
| WO2000040612A1 (en) | 1999-01-06 | 2000-07-13 | Genentech, Inc. | Insulin-like growth factor (igf) i mutant variants |
| DK1282437T3 (da) | 2000-05-16 | 2008-06-30 | Genentech Inc | Behandling af brusklidelser |
| CA2702192A1 (en) | 2001-03-14 | 2002-09-19 | Genentech, Inc. | Igf antagonist peptides |
| ATE536186T1 (de) | 2003-09-12 | 2011-12-15 | Tercica Inc | Verfahren zur behandlung von igf-1 (insulin-like growth factor 1)-mangel |
| WO2005033132A2 (en) | 2003-10-03 | 2005-04-14 | Genentech, Inc. | Igf binding proteins |
| BR112020004760A2 (pt) | 2017-09-11 | 2020-09-15 | Shire Human Genetic Therapies, Inc | métodos e composições para tratamento de doenças pulmonares crônicas |
| HUE070409T2 (hu) | 2020-10-19 | 2025-06-28 | Oak Hill Bio Ltd | Újszülötteknél alkalmazható készítmények |
| EP4466281A1 (de) | 2022-01-19 | 2024-11-27 | Oak Hill Bio Limited | Zusammensetzungen und verfahren zur verminderung der oxidation von igf1/igfbp |
| WO2023242440A1 (en) | 2022-06-17 | 2023-12-21 | Oak Hill Bio Limited | Treament of lungs in infants |
| WO2023242442A1 (en) | 2022-06-17 | 2023-12-21 | Oak Hill Bio Limited | Method of maturing/differentiating neurons and/or modulating the vagus nerve |
| WO2023242439A1 (en) | 2022-06-17 | 2023-12-21 | Oak Hill Bio Limited | Vascular stabilisation (preterm infants) |
| AU2024220592A1 (en) | 2023-02-14 | 2025-07-03 | Ann and Robert Lurie Children's Hospital of Chicago | Treatment of healing dysregulation in gi tissue |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4394443A (en) * | 1980-12-18 | 1983-07-19 | Yale University | Method for cloning genes |
| CA1209501A (en) * | 1982-09-16 | 1986-08-12 | Nikos Panayotatos | Expression vector |
| JP2648951B2 (ja) * | 1987-04-06 | 1997-09-03 | セルトリックス ファーマシュウティカルズ，インク | 人体のソマトメジン担体蛋白質サブユニットとこれらの製法 |
| DK131988A (da) * | 1988-03-11 | 1989-09-12 | Erasmus University | Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur |
-
1988
- 1988-06-03 AT AT88905539T patent/ATE132164T1/de not_active IP Right Cessation
- 1988-06-03 WO PCT/US1988/001885 patent/WO1989009792A1/en active IP Right Grant
- 1988-06-03 AU AU19553/88A patent/AU1955388A/en not_active Abandoned
- 1988-06-03 DE DE3854842T patent/DE3854842T2/de not_active Expired - Fee Related
- 1988-06-03 JP JP63505194A patent/JPH03504597A/ja active Pending
- 1988-06-03 EP EP88905539A patent/EP0418230B1/de not_active Expired - Lifetime
-
1989
- 1989-04-11 BR BR898901711A patent/BR8901711A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0418230A1 (de) | 1991-03-27 |
| AU1955388A (en) | 1989-11-03 |
| EP0418230A4 (en) | 1991-10-23 |
| JPH03504597A (ja) | 1991-10-09 |
| EP0418230B1 (de) | 1995-12-27 |
| DE3854842T2 (de) | 1996-06-13 |
| BR8901711A (pt) | 1989-11-21 |
| DE3854842D1 (de) | 1996-02-08 |
| WO1989009792A1 (en) | 1989-10-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |