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ATE130764T1 - Anti-idiotyp antikörper induktion eines antitumorenresponses. - Google Patents

Anti-idiotyp antikörper induktion eines antitumorenresponses.

Info

Publication number
ATE130764T1
ATE130764T1 AT89911726T AT89911726T ATE130764T1 AT E130764 T1 ATE130764 T1 AT E130764T1 AT 89911726 T AT89911726 T AT 89911726T AT 89911726 T AT89911726 T AT 89911726T AT E130764 T1 ATE130764 T1 AT E130764T1
Authority
AT
Austria
Prior art keywords
idiotype antibodies
antitumor response
patient
immune system
antibodies induction
Prior art date
Application number
AT89911726T
Other languages
English (en)
Inventor
Robert William Baldwin
Linda Gillian Durrant
Eric Bertram Austin
Vera S Byers
Original Assignee
Cancer Res Campaign Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Res Campaign Tech filed Critical Cancer Res Campaign Tech
Application granted granted Critical
Publication of ATE130764T1 publication Critical patent/ATE130764T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • C07K16/4266—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig against anti-tumor receptor Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT89911726T 1988-10-17 1989-10-13 Anti-idiotyp antikörper induktion eines antitumorenresponses. ATE130764T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25891188A 1988-10-17 1988-10-17

Publications (1)

Publication Number Publication Date
ATE130764T1 true ATE130764T1 (de) 1995-12-15

Family

ID=22982661

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89911726T ATE130764T1 (de) 1988-10-17 1989-10-13 Anti-idiotyp antikörper induktion eines antitumorenresponses.

Country Status (9)

Country Link
US (1) US6042827A (de)
EP (1) EP0440689B1 (de)
JP (1) JP3095169B2 (de)
AT (1) ATE130764T1 (de)
AU (1) AU634181B2 (de)
DE (1) DE68924983T2 (de)
IL (1) IL92009A (de)
NZ (1) NZ231037A (de)
WO (1) WO1990004415A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69422809T2 (de) * 1993-05-27 2000-10-12 Harald Schlebusch Monoklonale anti-idiotypische anti - CA125 Antikörper und sie enthaltende pharmazeutische Zusammensetzung
WO1997032021A1 (en) * 1996-02-28 1997-09-04 Cancer Research Campaign Technology Limited Therapeutic agents based on monoclonal anti-idiotypic antibody 105ad7
EP1157041B1 (de) 1999-03-01 2005-06-01 Genentech, Inc. Antikörper zur krebsbehandlung und -diagnose
DE10352977A1 (de) * 2003-11-13 2005-06-09 Müller-Hermelink, Hans Konrad, Prof. Dr. Muriner anti Idiotyp-Antikörpers oder anti Idiotyp-Antikörper aus der Ratte des humanen monoklonalen SC-1 Antikörpers
CN101355928B (zh) 2005-04-26 2013-05-22 卫材R&D管理株式会社 用于癌症免疫疗法的组合物和方法
EP1801594A1 (de) * 2005-12-23 2007-06-27 Koninklijke Philips Electronics N.V. Messvorrichtung und Verfahren zur Bestimmung der Anzahl an Zielmolekülen in einem Analyt
CN102764435B (zh) * 2012-08-03 2014-04-16 中国农业科学院兰州兽医研究所 一种猪用亚洲i型口蹄疫病毒灭活疫苗佐剂及制备方法
EP4021501A4 (de) * 2019-09-10 2023-09-13 The Research Foundation for The State University of New York Zusammensetzungen und verfahren zum verbessern der tumorpenetration von tumorspezifischen antikörpern

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708862A (en) * 1983-02-22 1987-11-24 Xoma Corporation Radioimmuno detection of human cancers using anti-tumor monoclonal antibody
US4699880A (en) * 1984-09-25 1987-10-13 Immunomedics, Inc. Method of producing monoclonal anti-idiotype antibody
US4918164A (en) * 1987-09-10 1990-04-17 Oncogen Tumor immunotherapy using anti-idiotypic antibodies
US4699830A (en) * 1986-06-30 1987-10-13 Baxter Travenol Laboratories, Inc. Laminated sheet material for packaging electronic components

Also Published As

Publication number Publication date
NZ231037A (en) 1992-03-26
WO1990004415A1 (en) 1990-05-03
EP0440689A4 (en) 1991-11-27
AU4410489A (en) 1990-05-14
JPH04501061A (ja) 1992-02-27
EP0440689A1 (de) 1991-08-14
IL92009A (en) 1994-12-29
EP0440689B1 (de) 1995-11-29
DE68924983D1 (de) 1996-01-11
JP3095169B2 (ja) 2000-10-03
AU634181B2 (en) 1993-02-18
DE68924983T2 (de) 1996-06-20
IL92009A0 (en) 1990-07-12
US6042827A (en) 2000-03-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time