[go: up one dir, main page]

ATE112764T1 - Diphenylpiperazinderivat. - Google Patents

Diphenylpiperazinderivat.

Info

Publication number
ATE112764T1
ATE112764T1 AT91912316T AT91912316T ATE112764T1 AT E112764 T1 ATE112764 T1 AT E112764T1 AT 91912316 T AT91912316 T AT 91912316T AT 91912316 T AT91912316 T AT 91912316T AT E112764 T1 ATE112764 T1 AT E112764T1
Authority
AT
Austria
Prior art keywords
action
cardiac muscles
diphenylpiperazine
derivative
diphenylpiperazine derivative
Prior art date
Application number
AT91912316T
Other languages
English (en)
Inventor
Noboru Kaneko
Makoto Takeishi
Tatsushi Kirinbeer K K Oosawa
Miyahara-Cho
Kouji Kirinbeer K K Akimoto
Hideo Kirinbeer K K Oota
Cho
Tatsuo Kirinbeer K K Nakajima
Original Assignee
Noboru Kaneko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noboru Kaneko filed Critical Noboru Kaneko
Application granted granted Critical
Publication of ATE112764T1 publication Critical patent/ATE112764T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT91912316T 1990-07-10 1991-07-10 Diphenylpiperazinderivat. ATE112764T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2182095A JP2651043B2 (ja) 1990-07-10 1990-07-10 ジフェニルメチルピペラジン誘導体

Publications (1)

Publication Number Publication Date
ATE112764T1 true ATE112764T1 (de) 1994-10-15

Family

ID=16112265

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91912316T ATE112764T1 (de) 1990-07-10 1991-07-10 Diphenylpiperazinderivat.

Country Status (12)

Country Link
US (1) US5304558A (de)
EP (1) EP0541802B1 (de)
JP (1) JP2651043B2 (de)
CN (1) CN1037840C (de)
AT (1) ATE112764T1 (de)
AU (1) AU8212591A (de)
CA (1) CA2087032C (de)
DE (1) DE69104615T2 (de)
RU (1) RU2091379C1 (de)
TW (1) TW198717B (de)
WO (1) WO1992000962A1 (de)
ZA (1) ZA915366B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5658963A (en) * 1995-02-02 1997-08-19 Bisco, Inc. One-component primer/bonding-resin systems
AU776745B2 (en) * 1999-09-30 2004-09-23 Noboru Kaneko Anticancer agents
JP2003528867A (ja) * 2000-03-31 2003-09-30 ファイザー・プロダクツ・インク 新規ピぺラジン誘導体
US20040229781A1 (en) * 2000-05-10 2004-11-18 Marks Andrew Robert Compounds and methods for treating and preventing exercise-induced cardiac arrhythmias
US7718644B2 (en) * 2004-01-22 2010-05-18 The Trustees Of Columbia University In The City Of New York Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof
US8022058B2 (en) 2000-05-10 2011-09-20 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US20060293266A1 (en) * 2000-05-10 2006-12-28 The Trustees Of Columbia Phosphodiesterase 4D in the ryanodine receptor complex protects against heart failure
US7393652B2 (en) * 2000-05-10 2008-07-01 The Trustees Of Columbia University In The City Of New York Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2)
US7879840B2 (en) * 2005-08-25 2011-02-01 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US6489125B1 (en) * 2000-05-10 2002-12-03 The Trustees Of Columbia University In The City Of New York Methods for identifying chemical compounds that inhibit dissociation of FKBP12.6 binding protein from type 2 ryanodine receptor
US20040048780A1 (en) * 2000-05-10 2004-03-11 The Trustees Of Columbia University In The City Of New York Method for treating and preventing cardiac arrhythmia
JP4320252B2 (ja) * 2001-09-06 2009-08-26 シェーリング コーポレイション アンドロゲン依存性疾患の処置のための１β−ヒドロキシステロイドデヒドロゲナーゼ３型インヒビター
US7544678B2 (en) * 2002-11-05 2009-06-09 The Trustees Of Columbia University In The City Of New York Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2)
AU2004220548A1 (en) 2003-03-07 2004-09-23 The Trustees Of Columbia University, In The City Of New York Type 1 ryanodine receptor-based methods
US8710045B2 (en) * 2004-01-22 2014-04-29 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the ryanodine receptors
US7704990B2 (en) * 2005-08-25 2010-04-27 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
JP5318938B2 (ja) * 2011-06-09 2013-10-16 株式会社アエタスファルマ ジフェニルメチルピペラジン誘導体、及びそれを用いた医薬組成物
JP6021616B2 (ja) * 2012-12-04 2016-11-09 株式会社アエタスファルマ ３−ピペラジニル−１−ピペリジニル−プロパン誘導体及びそれを含有してなる医薬組成物
KR102257892B1 (ko) 2014-11-26 2021-05-28 삼성전자주식회사 개선된 ｎｆｃ 안테나 및 그 안테나를 갖는 전자 장치

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR65270B (en) * 1978-10-10 1980-07-31 Fujisawa Pharmaceutical Co Isatin derivatives and processes for the preparation thereof
DE3536797A1 (de) * 1985-10-16 1987-04-16 Studiengesellschaft Kohle Mbh Verfahren zur herstellung von halogen-magnesium-alanat und dessen verwendung
NL8700245A (nl) * 1986-02-14 1987-09-01 Sandoz Ag Purinederivaten, werkwijzen voor hun bereiding en geneesmiddelen die deze derivaten bevatten.
ZA871078B (en) * 1986-02-14 1988-09-28 Sandoz Ltd Purine derivatives,their preparation and medicaments containing them
US4885300A (en) * 1988-03-03 1989-12-05 Ortho Pharmaceutical Corporation 4-Substituted pyrazolo[3,4-D]pyrimidine derivatives
US5215987A (en) * 1990-04-23 1993-06-01 Ortho Pharmaceutical Corporation Substituted benzhydryl 2-hydroxypropyl piperazine derivatives

Also Published As

Publication number Publication date
TW198717B (de) 1993-01-21
JPH0469377A (ja) 1992-03-04
WO1992000962A1 (fr) 1992-01-23
CA2087032C (en) 1999-06-15
AU8212591A (en) 1992-02-04
CN1037840C (zh) 1998-03-25
DE69104615D1 (de) 1994-11-17
CN1058963A (zh) 1992-02-26
EP0541802A4 (en) 1993-05-26
EP0541802B1 (de) 1994-10-12
EP0541802A1 (de) 1993-05-19
DE69104615T2 (de) 1995-03-23
CA2087032A1 (en) 1992-01-11
ZA915366B (en) 1992-04-29
RU2091379C1 (ru) 1997-09-27
US5304558A (en) 1994-04-19
JP2651043B2 (ja) 1997-09-10

Similar Documents

Publication Publication Date Title
DE69104615D1 (de) Diphenylpiperazinderivat.
NO894738L (no) Substituerte thiazoler og deres anvendelse som fungicider.
DK0486948T3 (da) Forbindelser, der hæmmer retrovirale proteaser
DE69407409D1 (de) Azolylamin-derivat
ATE269290T1 (de) Benzoylderivate
NZ237565A (en) Substituted thiazolidinones, oxazolidinones or imidazolidinones and antiinflammatory pharmaceutical compositions thereof
NO307047B1 (no) Nye hydroksyetylaminosulfonamider som er nyttige som retrovirale proteasehemmere, farmasøytisk preparat inneholdende slike, og anvendelse derav
DE69820248D1 (de) Pyrrolidin-derivate die eine phospholipase-a2-hemmende wirkung haben
GR3020953T3 (en) Agents for preserving wood or composite-wood materials against insects
NO944371D0 (no) Kjemisk forbindelse med blodplateaggregeringsinhiberende virkning
ATE121621T1 (de) Verwendung von tetrahydrothienopyridinderivate als angiogenese-inhibitoren.
DE50101861D1 (de) Tocotrienolchinon- zyklisierungsprodukte mit antihypercholesterin wirkung
ATE156486T1 (de) Fungizide 3,4-diaryl-(5h)-furan-2-onederivate
DK0530639T3 (da) Heterocyclisk substituerede quinolylmethoxy-phenylacetamider som lipoxygenasehæmmere
ES2191763T3 (es) Inhibidor del desarrollo de dependencia/tolerancia a un agente analgesico narcotico.
IL82382A (en) N-(pyrid-3-yl)cyclopropane carboxamides and their use as fungicides
ATE88634T1 (de) Arzneimittel zur behandlung von herzinsuffizienz.
ATE114309T1 (de) N-azabicyclo(3.3.0>octanamide von aromatischen säuren.
DE69012289D1 (de) Fungizide.
EP0653207A4 (de) Aids-virus-infektion hemmende zusammensetzung.
DE69213049D1 (de) Isoquinolinderivate
ES2115178T3 (es) Derivados de indanotrionas y de hidrazidas y su aplicacion terapeutica.
ATE154243T1 (de) Hemmstoff der blutgefässhypertrophie
KR960702310A (ko) 도파민 재소비 저해제

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time