ATA185885A - Verfahren zur herstellung des neuen 3-amino-4-(2-((2-guanidinothiazol-4-yl)methylth o)-ethylamino)-1,2,5-thiadiazols - Google Patents

Verfahren zur herstellung des neuen 3-amino-4-(2-((2-guanidinothiazol-4-yl)methylth o)-ethylamino)-1,2,5-thiadiazols

Info

Publication number: ATA185885A
Authority: AT; Austria
Prior art keywords: guanidinothiazol; methylth; thiadiazol; ethylamino; amino
Prior art date: 1984-06-22

Application number

AT0185885A

Other languages

English (en)

Other versions

AT390790B (de

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-06-22

Filing date

1985-06-21

Publication date

1989-12-15

1985-06-21 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1989-07-25 Priority to AT0179289A priority Critical patent/ATA179289A/de

1989-11-15 Priority to AT0260889A priority patent/ATA260889A/de

1989-12-15 Publication of ATA185885A publication Critical patent/ATA185885A/de

1990-06-25 Application granted granted Critical

1990-06-25 Publication of AT390790B publication Critical patent/AT390790B/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

AT0185885A 1984-06-22 1985-06-21 Verfahren zur herstellung des neuen 3-amino-4-(2-((2-guanidinothiazol-4-yl)methylth o)-ethylamino)-1,2,5-thiadiazols AT390790B (de)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
AT0179289A ATA179289A (de)	1984-06-22	1989-07-25	Verfahren zur herstellung des neuen n-(2-((2guanidinothiazol-4-yl)methyl-thio)ethyl)ethandiimidamids
AT0260889A ATA260889A (de)	1984-06-22	1989-11-15	Verfahren zur herstellung des neuen n-(2-( (2-guanidinothiazol-4-yl)methylthio)-ethyl)- ethandiimidamids

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/623,588 US4644006A (en)	1984-06-22	1984-06-22	Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity

Publications (2)

Publication Number	Publication Date
ATA185885A true ATA185885A (de)	1989-12-15
AT390790B AT390790B (de)	1990-06-25

Family

ID=24498651

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT0185885A AT390790B (de)	1984-06-22	1985-06-21	Verfahren zur herstellung des neuen 3-amino-4-(2-((2-guanidinothiazol-4-yl)methylth o)-ethylamino)-1,2,5-thiadiazols

Country Status (33)

Country	Link
US (1)	US4644006A (de)
JP (2)	JPS6118775A (de)
KR (1)	KR900004321B1 (de)
AR (1)	AR240935A1 (de)
AT (1)	AT390790B (de)
AU (2)	AU580605B2 (de)
BE (1)	BE902724A (de)
CA (2)	CA1267412A (de)
CH (1)	CH665210A5 (de)
CS (1)	CS257276B2 (de)
DD (1)	DD240889A5 (de)
DE (1)	DE3522101A1 (de)
DK (1)	DK282885A (de)
ES (2)	ES8702902A1 (de)
FI (1)	FI852405L (de)
FR (1)	FR2566406B1 (de)
GB (2)	GB2161157B (de)
GR (1)	GR851514B (de)
HU (1)	HU193992B (de)
IE (2)	IE57937B1 (de)
IL (1)	IL75567A0 (de)
IT (1)	IT1190372B (de)
LU (1)	LU85969A1 (de)
NL (1)	NL8501766A (de)
NO (1)	NO161856C (de)
NZ (1)	NZ212403A (de)
OA (1)	OA08039A (de)
PT (1)	PT80684B (de)
SE (1)	SE464305B (de)
SU (1)	SU1537136A3 (de)
YU (2)	YU45725B (de)
ZA (1)	ZA854710B (de)
ZW (1)	ZW10385A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1991018882A1 (en) *	1990-05-29	1991-12-12	Nippon Soda Co., Ltd.	N-substituted heterocyclic amidine derivative
EP4196793A1 (de)	2020-08-11	2023-06-21	Université de Strasbourg	Auf lebermakrophagen abzielende h2-blocker zur prävention und behandlung von lebererkrankungen und krebs

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3657237A (en) *	1968-05-22	1972-04-18	Frosst & Co Charles E	Process for making 1 2 5-thiadiazoles in the sinister configuration
DK160611C (da) *	1979-09-04	1991-09-16	Bristol Myers Squibb Co	Analogifremgangsmaade til fremstilling af 3,4-disubstituerede 1,2,5-thiadiazol-1-oxider og -1,1-dioxider
EP0040696B1 (de) *	1980-04-30	1986-08-27	Merck & Co. Inc.	Aminothiadiazole als gastrische Inhibitoren
US4394508A (en) *	1980-06-07	1983-07-19	Bristol-Myers Company	Chemical compounds
DE3168031D1 (en) *	1980-07-30	1985-02-14	Ici Plc	Guanidine derivatives
EP0060730A3 (de) *	1981-03-18	1982-12-08	Imperial Chemical Industries Plc	Bicyclische Derivate
EP0065823A1 (de) *	1981-05-13	1982-12-01	Imperial Chemical Industries Plc	Heterozyklische Guanidinderivate als Histamin-H-2-Antagonisten
FR2542741B1 (fr) *	1982-03-29	1989-12-08	Bristol Myers Co	3,4-diamino-1,2,5-thiadiazoles substitues possedant une activite antagoniste du recepteur-h2 de l'histamine
US4588826A (en) *	1982-03-29	1986-05-13	Bristol-Myers Company	Ethanediimidamide intermediates
US4528377A (en) *	1982-03-29	1985-07-09	Bristol-Myers Company	Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity
US4517366A (en) *	1982-03-29	1985-05-14	Bristol-Myers Company	Intermediates for preparing 3,4-diamino-1,2,5-thiadiazoles
US4528378A (en) *	1982-03-29	1985-07-09	Bristol-Myers Company	Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity
US4528375A (en) *	1982-03-29	1985-07-09	Bristol-Myers Company	Substituted 3,4-diamino-1,2,5-thiadiazoles having histamine H2 -receptor antagonist activity
FI832519L (fi) *	1982-07-12	1984-01-13	Bristol Myers Co	Farmaceutiska foerfaranden och sammansaettningar
US4520025A (en) *	1982-07-21	1985-05-28	William H. Rorer, Inc.	Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
JPS5978171A (ja) *	1982-10-26	1984-05-04	Ikeda Mohandou:Kk	複素環式化合物
US4440933A (en) *	1983-03-16	1984-04-03	Bristol-Myers Company	Process for preparing 1,2,5-thiadiazoles

1984
- 1984-06-22 US US06/623,588 patent/US4644006A/en not_active Expired - Fee Related
1985
- 1985-06-05 SU SU853906050A patent/SU1537136A3/ru active
- 1985-06-07 CA CA000483419A patent/CA1267412A/en not_active Expired - Lifetime
- 1985-06-07 FR FR8508668A patent/FR2566406B1/fr not_active Expired
- 1985-06-12 CS CS854247A patent/CS257276B2/cs unknown
- 1985-06-13 NZ NZ212403A patent/NZ212403A/xx unknown
- 1985-06-17 FI FI852405A patent/FI852405L/fi not_active Application Discontinuation
- 1985-06-19 AR AR300752A patent/AR240935A1/es active
- 1985-06-19 IL IL75567A patent/IL75567A0/xx not_active IP Right Cessation
- 1985-06-19 NL NL8501766A patent/NL8501766A/nl not_active Application Discontinuation
- 1985-06-19 DD DD85277533A patent/DD240889A5/de not_active IP Right Cessation
- 1985-06-20 GR GR851514A patent/GR851514B/el unknown
- 1985-06-20 SE SE8503110A patent/SE464305B/sv not_active IP Right Cessation
- 1985-06-20 KR KR1019850004457A patent/KR900004321B1/ko not_active IP Right Cessation
- 1985-06-20 IT IT21217/85A patent/IT1190372B/it active
- 1985-06-20 DE DE19853522101 patent/DE3522101A1/de not_active Withdrawn
- 1985-06-21 ZA ZA854710A patent/ZA854710B/xx unknown
- 1985-06-21 PT PT80684A patent/PT80684B/pt not_active IP Right Cessation
- 1985-06-21 DK DK282885A patent/DK282885A/da unknown
- 1985-06-21 HU HU852443A patent/HU193992B/hu not_active IP Right Cessation
- 1985-06-21 AU AU43920/85A patent/AU580605B2/en not_active Ceased
- 1985-06-21 ES ES544409A patent/ES8702902A1/es not_active Expired
- 1985-06-21 NO NO852519A patent/NO161856C/no unknown
- 1985-06-21 IE IE501/89A patent/IE57937B1/en not_active IP Right Cessation
- 1985-06-21 CH CH2657/85A patent/CH665210A5/de not_active IP Right Cessation
- 1985-06-21 GB GB08515749A patent/GB2161157B/en not_active Expired
- 1985-06-21 AT AT0185885A patent/AT390790B/de not_active IP Right Cessation
- 1985-06-21 IE IE155785A patent/IE58261B1/en not_active IP Right Cessation
- 1985-06-21 JP JP60135861A patent/JPS6118775A/ja active Pending
- 1985-06-21 LU LU85969A patent/LU85969A1/fr unknown
- 1985-06-21 ZW ZW103/85A patent/ZW10385A1/xx unknown
- 1985-06-21 BE BE0/215242A patent/BE902724A/fr not_active IP Right Cessation
- 1985-06-24 YU YU105185A patent/YU45725B/sh unknown
- 1985-08-18 OA OA58614A patent/OA08039A/xx unknown
- 1985-10-04 JP JP60221721A patent/JPS61186369A/ja active Pending
1986
- 1986-01-31 ES ES551506A patent/ES8702881A1/es not_active Expired
1987
- 1987-06-03 YU YU102587A patent/YU45822B/sh unknown
- 1987-07-09 GB GB08716149A patent/GB2192884B/en not_active Expired
1989
- 1989-02-08 AU AU29775/89A patent/AU614331B2/en not_active Ceased
- 1989-05-12 CA CA000599622A patent/CA1297875C/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DK282885A (da)	1985-12-23
NL8501766A (nl)	1986-01-16
NO161856C (no)	1989-10-04
YU105185A (en)	1987-12-31
US4644006A (en)	1987-02-17
HU193992B (en)	1987-12-28
OA08039A (fr)	1987-01-31
LU85969A1 (fr)	1986-01-24
YU45725B (sh)	1992-07-20
GR851514B (de)	1985-11-25
IL75567A0 (en)	1985-10-31
CH665210A5 (de)	1988-04-29
JPS6118775A (ja)	1986-01-27
HUT42087A (en)	1987-06-29
AT390790B (de)	1990-06-25
KR900004321B1 (ko)	1990-06-22
SE8503110D0 (sv)	1985-06-20
ZW10385A1 (en)	1986-02-05
KR860000275A (ko)	1986-01-27
AU2977589A (en)	1989-06-01
GB2161157B (en)	1988-08-10
IE58261B1 (en)	1993-08-25
IT8521217A0 (it)	1985-06-20
SE464305B (sv)	1991-04-08
FR2566406B1 (fr)	1988-01-29
AU580605B2 (en)	1989-01-19
GB2161157A (en)	1986-01-08
GB8515749D0 (en)	1985-07-24
AR240935A1 (es)	1991-03-27
ES8702881A1 (es)	1987-01-16
YU102587A (en)	1988-02-29
ES8702902A1 (es)	1987-01-16
ZA854710B (en)	1986-02-26
SU1537136A3 (ru)	1990-01-15
AU4392085A (en)	1986-01-02
DK282885D0 (da)	1985-06-21
ES544409A0 (es)	1987-01-16
JPS61186369A (ja)	1986-08-20
CA1267412A (en)	1990-04-03
NO161856B (no)	1989-06-26
CS424785A2 (en)	1987-09-17
SE8503110L (sv)	1985-12-23
DE3522101A1 (de)	1986-01-02
AU614331B2 (en)	1991-08-29
CA1297875C (en)	1992-03-24
PT80684A (en)	1985-07-01
ES551506A0 (es)	1987-01-16
IE851557L (en)	1985-12-22
IE57937B1 (en)	1993-05-19
AR240935A2 (es)	1991-03-27
PT80684B (en)	1987-05-08
DD240889A5 (de)	1986-11-19
NZ212403A (en)	1989-04-26
FI852405L (fi)	1985-12-23
FR2566406A1 (fr)	1985-12-27
YU45822B (sh)	1992-07-20
GB8716149D0 (en)	1987-08-12
BE902724A (fr)	1985-12-23
IT1190372B (it)	1988-02-16
FI852405A0 (fi)	1985-06-17
CS257276B2 (en)	1988-04-15
GB2192884B (en)	1988-08-10
NO852519L (no)	1985-12-23
GB2192884A (en)	1988-01-27

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DE59000326D1 (de)	1992-11-05	Verfahren zur herstellung von 3-amino-5-aminocarbonyl-1,2,4-triazol-derivaten.
DE3675687D1 (de)	1991-01-03	Verfahren zur herstellung von 2,2,6,6,-tetraalkyl-4-piperidylamine.
AT386414B (de)	1988-08-25	Verfahren zur herstellung des neuen 2'-acetylery- thromycinstearates
DE3667167D1 (de)	1990-01-04	Verfahren zur herstellung von 1,5-diazido-3-nitrazapentan.
DE3677272D1 (de)	1991-03-07	Verfahren zur herstellung von 2,2,6,6-tetraalkyl-4-piperidylaminen.
DE3676215D1 (de)	1991-01-31	Verfahren zur herstellung von 2,3,4,5-tetrafluorbenzoesaeure.
DE3680454D1 (de)	1991-08-29	Verfahren zur herstellung von halogenhaltigen (2,2)-paracyclophanen.
DE3860671D1 (de)	1990-10-31	Verfahren zur herstellung von 2,6-dialkylnaphthalin.
DE3674055D1 (de)	1990-10-18	Verfahren zur herstellung von 1,3,5-triazintrionen.
DE3861825D1 (de)	1991-04-04	Verfahren zur herstellung von (2,2)-paracyclophan.
DE3673049D1 (de)	1990-09-06	Verfahren zur herstellung von 1,3-dialkyl-2-imidazolidinon.
DE3581884D1 (de)	1991-04-04	Verfahren zur herstellung von 2,2'-methylen-bis-(4-hydrocarbyl-6-benzotriazolyl(phenolen).
DE3765956D1 (de)	1990-12-13	Verfahren zur herstellung von 1-methyl-3,5,7-triaza-1-azoniatricyclodecan-halogeniden.
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AT373892B (de)	1984-02-27	Verfahren zur herstellung des neuen kristallinen 1,1-dioxopenicillanoyloxymethyl-6-(d-alpha-amin
DE3669148D1 (de)	1990-04-05	Verfahren zur herstellung von 4,4'-dinitrodibenzylen.
AT387776B (de)	1989-03-10	Verfahren zur herstellung von neuem 8alphapivaloylamino-9,10-didehydro-ergolin
ATA185885A (de)	1989-12-15	Verfahren zur herstellung des neuen 3-amino-4-(2-((2-guanidinothiazol-4-yl)methylth o)-ethylamino)-1,2,5-thiadiazols
DE3671436D1 (de)	1990-06-28	Verfahren zur herstellung von 2,2,-dibrom-3-oxonitrilen.
AT380881B (de)	1986-07-25	Verfahren zur herstellung des neuen 3-(4-phenyl-1-piperazinio-1-yl)-1,2-propandiol-(theophyllin-7-yl)-1-propansulfonats
AT374203B (de)	1984-03-26	Verfahren zur herstellung von neuen 2'-desoxy-3', 5'-di-o-alkylcarbonyl-5-fluoruridinderivaten
AT380233B (de)	1986-04-25	Verfahren zur herstellung von neuen 1,7,7
AT371442B (de)	1983-06-27	Verfahren zur herstellung des neuen 1-(2-chlorbenzyl)-1,2,3,6-tetrahydropyridins
AT388730B (de)	1989-08-25	Verfahren zur herstellung von neuen azabicyclo (3,3,1) - nonan- derivaten
DE3574585D1 (de)	1990-01-11	Verfahren zur herstellung von 3,5-dialkyl-4-hydroxybenzoesaeure.

Legal Events

Date	Code	Title	Description
1994-09-15	ELJ	Ceased due to non-payment of the annual fee
2002-09-15	REN	Ceased due to non-payment of the annual fee