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AT381092B - Verfahren zur herstellung von neuen substituierten pyrrolo-(2,1-b)-chinazolinen und pyrido(2,1-b)- chinazolinen, ihren isomeren und deren gemischen und ihren pharmazeutisch unbedenklichen salzen - Google Patents

Verfahren zur herstellung von neuen substituierten pyrrolo-(2,1-b)-chinazolinen und pyrido(2,1-b)- chinazolinen, ihren isomeren und deren gemischen und ihren pharmazeutisch unbedenklichen salzen

Info

Publication number
AT381092B
AT381092B AT0247582A AT247582A AT381092B AT 381092 B AT381092 B AT 381092B AT 0247582 A AT0247582 A AT 0247582A AT 247582 A AT247582 A AT 247582A AT 381092 B AT381092 B AT 381092B
Authority
AT
Austria
Prior art keywords
chinazolines
quinazolines
pyrido
isomers
mixtures
Prior art date
Application number
AT0247582A
Other languages
English (en)
Other versions
ATA247582A (de
Inventor
Gianfederico Doria
Carlo Passarotti
Giuliana Arcari
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of ATA247582A publication Critical patent/ATA247582A/de
Application granted granted Critical
Publication of AT381092B publication Critical patent/AT381092B/de

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K1/00—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces
    • F16K1/16—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces with pivoted closure-members
    • F16K1/18—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces with pivoted closure-members with pivoted discs or flaps
    • F16K1/22—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces with pivoted closure-members with pivoted discs or flaps with axis of rotation crossing the valve member, e.g. butterfly valves
    • F16K1/226—Shaping or arrangements of the sealing
    • F16K1/2263—Shaping or arrangements of the sealing the sealing being arranged on the valve seat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K1/00—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces
    • F16K1/16—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces with pivoted closure-members
    • F16K1/18—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces with pivoted closure-members with pivoted discs or flaps
    • F16K1/22—Lift valves or globe valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces with pivoted closure-members with pivoted discs or flaps with axis of rotation crossing the valve member, e.g. butterfly valves
    • F16K1/226—Shaping or arrangements of the sealing
    • F16K1/2268—Sealing means for the axis of rotation

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT0247582A 1981-06-30 1982-06-25 Verfahren zur herstellung von neuen substituierten pyrrolo-(2,1-b)-chinazolinen und pyrido(2,1-b)- chinazolinen, ihren isomeren und deren gemischen und ihren pharmazeutisch unbedenklichen salzen AT381092B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8120126 1981-06-30

Publications (2)

Publication Number Publication Date
ATA247582A ATA247582A (de) 1986-01-15
AT381092B true AT381092B (de) 1986-08-25

Family

ID=10522894

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0775378A AT377586B (de) 1981-06-30 1978-10-30 Verfahren zur herstellung von substituierten pyrrolo-(2,1-b)-chinazolinen und pyrido(2,1-b)chinazolinen
AT0247582A AT381092B (de) 1981-06-30 1982-06-25 Verfahren zur herstellung von neuen substituierten pyrrolo-(2,1-b)-chinazolinen und pyrido(2,1-b)- chinazolinen, ihren isomeren und deren gemischen und ihren pharmazeutisch unbedenklichen salzen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0775378A AT377586B (de) 1981-06-30 1978-10-30 Verfahren zur herstellung von substituierten pyrrolo-(2,1-b)-chinazolinen und pyrido(2,1-b)chinazolinen

Country Status (18)

Country Link
US (1) US4428952A (de)
JP (1) JPS588082A (de)
AT (2) AT377586B (de)
AU (1) AU552065B2 (de)
BE (1) BE893694A (de)
CA (1) CA1183135A (de)
CH (1) CH657618A5 (de)
DE (1) DE3224213A1 (de)
DK (1) DK292782A (de)
FI (1) FI73997C (de)
FR (1) FR2508457B1 (de)
GB (1) GB2103207B (de)
IL (1) IL66146A (de)
IT (1) IT1159069B (de)
NL (1) NL8202602A (de)
SE (1) SE448096B (de)
SU (1) SU1279530A1 (de)
ZA (1) ZA824502B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU553266B2 (en) * 1982-02-04 1986-07-10 Farmitalia Carlo Erba S.P.A. Substituted 1,3,4-thiadiazolo(3,2-a) pyrimidines
ES521739A0 (es) * 1982-04-29 1984-07-01 Erba Farmitalia Procedimiento para preparar derivados cicloalifaticos condensados de pirido(1,2-a)pirimidinas sustituidas.
IL69274A (en) * 1982-08-05 1986-08-31 Erba Farmitalia (substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them
CA2113115A1 (en) * 1991-07-29 1993-02-18 Vlad E. Gregor Quinazoline derivatives as acetylcholinesterase inhibitors
AU2001275279B2 (en) * 2000-06-07 2007-01-04 Vertex Pharmaceuticals Incorporated Caspase inhibitors and uses thereof
EP3661502A4 (de) * 2017-08-03 2020-12-02 Galectin Sciences, LLC Verbindungen zur vorbeugung und behandlung von erkrankungen und ihre verwendung

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3271396A (en) * 1964-08-17 1966-09-06 Squibb & Sons Inc Pyrido-quinazoline derivatives
DE2705778A1 (de) * 1976-02-12 1977-08-18 Chinoin Gyogyszer Es Vegyeszet Kondensierte pyrimidinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2992221A (en) * 1958-07-03 1961-07-11 Petersen Siegfried Polymethylene-oxoquinazolines and their production
DE1670416A1 (de) 1966-12-30 1971-02-11 Chem Fab Von Heyden Gmbh Muenc Verfahren zur Herstellung von aminosubstituierten Chinazolinonderivaten
DE2739020A1 (de) 1977-08-26 1979-03-01 Schering Ag Pyrido eckige klammer auf 2,1-b eckige klammer zu -chinazolinon-derivate, ihre herstellung und verwendung
US4310526A (en) 1979-05-08 1982-01-12 Farmitalia Carlo Erba S.P.A. Substituted 6,7-methylene pyrido[1,2-a]pyrimidines useful as anti-allergic and anti-ulcer agents
HU183173B (en) * 1980-06-24 1984-04-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 6-hydrazono-pyrido-aracket-2,1-b-bracket closed-quinazolin-11-ones

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3271396A (en) * 1964-08-17 1966-09-06 Squibb & Sons Inc Pyrido-quinazoline derivatives
DE2705778A1 (de) * 1976-02-12 1977-08-18 Chinoin Gyogyszer Es Vegyeszet Kondensierte pyrimidinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
GB2103207A (en) 1983-02-16
JPS588082A (ja) 1983-01-18
DE3224213A1 (de) 1983-01-27
FR2508457B1 (fr) 1985-08-30
SE8204034D0 (sv) 1982-06-29
CA1183135A (en) 1985-02-26
FI822329A0 (fi) 1982-06-30
ATA775378A (de) 1984-08-15
BE893694A (fr) 1982-12-29
IT8222005A0 (it) 1982-06-23
FI73997C (fi) 1987-12-10
AT377586B (de) 1985-04-10
SU1279530A3 (ru) 1986-12-23
NL8202602A (nl) 1983-01-17
FI822329L (fi) 1982-12-31
ZA824502B (en) 1983-04-27
IT1159069B (it) 1987-02-25
SU1279530A1 (ru) 1986-12-23
DK292782A (da) 1982-12-31
GB2103207B (en) 1985-01-09
SE448096B (sv) 1987-01-19
IL66146A0 (en) 1982-09-30
FR2508457A1 (fr) 1982-12-31
ATA247582A (de) 1986-01-15
SE8204034L (sv) 1982-12-31
IL66146A (en) 1985-12-31
AU552065B2 (en) 1986-05-22
AU8492282A (en) 1983-01-06
FI73997B (fi) 1987-08-31
CH657618A5 (de) 1986-09-15
US4428952A (en) 1984-01-31

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