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AT350518B - Verfahren zur herstellung von neuen, stereoisomeren 2-aminocyclohexan- oder -pentan- carbonsaeureamiden sowie von deren saeure- additionssalzen - Google Patents

Verfahren zur herstellung von neuen, stereoisomeren 2-aminocyclohexan- oder -pentan- carbonsaeureamiden sowie von deren saeure- additionssalzen

Info

Publication number
AT350518B
AT350518B AT395476A AT395476A AT350518B AT 350518 B AT350518 B AT 350518B AT 395476 A AT395476 A AT 395476A AT 395476 A AT395476 A AT 395476A AT 350518 B AT350518 B AT 350518B
Authority
AT
Austria
Prior art keywords
aminocyclohexane
stereoisomeric
pentane
new
production
Prior art date
Application number
AT395476A
Other languages
English (en)
Other versions
ATA395476A (de
Inventor
Gabor Dr Dipl Chem Bernath
Lajos Dr Dipl Chem Gera
Gyoergy Dr Dipl Chem Goendoes
Kalman Dr Dipl Chem Kovacs
Erzsebet Janvari
Gyula Dr Sebestyen
Zoltan Ecsery
Judit Dr Hermann
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of ATA395476A publication Critical patent/ATA395476A/de
Application granted granted Critical
Publication of AT350518B publication Critical patent/AT350518B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT395476A 1975-06-02 1976-05-31 Verfahren zur herstellung von neuen, stereoisomeren 2-aminocyclohexan- oder -pentan- carbonsaeureamiden sowie von deren saeure- additionssalzen AT350518B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI001580 HU177576B (en) 1975-06-02 1975-06-02 Process for preparing 2-amino-cyclohexane carboxylic acid,its amides and similar compounds

Publications (2)

Publication Number Publication Date
ATA395476A ATA395476A (de) 1978-11-15
AT350518B true AT350518B (de) 1979-06-11

Family

ID=10994566

Family Applications (2)

Application Number Title Priority Date Filing Date
AT395476A AT350518B (de) 1975-06-02 1976-05-31 Verfahren zur herstellung von neuen, stereoisomeren 2-aminocyclohexan- oder -pentan- carbonsaeureamiden sowie von deren saeure- additionssalzen
AT612777A AT346826B (de) 1975-06-02 1977-08-24 Verfahren zur herstellung von neuen, stereoisomeren 2-substituierten amino- cyclohexan- oder -pentancarbonsaeureamiden und deren saeureadditionssalzen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT612777A AT346826B (de) 1975-06-02 1977-08-24 Verfahren zur herstellung von neuen, stereoisomeren 2-substituierten amino- cyclohexan- oder -pentancarbonsaeureamiden und deren saeureadditionssalzen

Country Status (6)

Country Link
AT (2) AT350518B (de)
CS (1) CS217955B2 (de)
DE (1) DE2624290A1 (de)
FR (1) FR2313023A1 (de)
HU (1) HU177576B (de)
YU (2) YU129376A (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3125872A1 (de) * 1981-07-01 1983-01-20 Basf Ag, 6700 Ludwigshafen Schiff-basen von aminocycloalkancarbonsaeureestern, verfahren zu ihrer herstellung sowie ihre verwendung als zwischenprodukte
EP0214009A3 (de) * 1985-07-30 1989-01-11 Merck & Co. Inc. Enaminone als mögliche Prodrage von primären oder sekundären Aminen
GB8716278D0 (en) * 1987-07-10 1987-08-19 Fujisawa Pharmaceutical Co Antimicrobial agent
DE4033415A1 (de) * 1990-10-20 1992-04-23 Bayer Ag Antimikrobielle mittel sowie substituierte 2-cyclohexan-1-yl-amin-derivate und deren herstellung
AU673824B2 (en) * 1992-05-29 1996-11-28 Bayer Aktiengesellschaft Cyclopentane- and -pentene-beta-amino acids
US6462076B2 (en) 2000-06-14 2002-10-08 Hoffmann-La Roche Inc. Beta-amino acid nitrile derivatives as cathepsin K inhibitors
US6759428B2 (en) 2001-12-04 2004-07-06 Roche Palo Alto Llc Indole nitriles
PL370766A1 (en) 2001-12-04 2005-05-30 F.Hoffmann-La Roche Ag Substituted 2-amino-cycloalkanecarboxamides and their use as cysteine protease inhibitors
WO2004056744A1 (en) * 2002-12-23 2004-07-08 Janssen Pharmaceutica N.V. Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors
EP1533295A1 (de) * 2003-11-24 2005-05-25 Newron Pharmaceuticals S.p.A. Cyclopentylderivate
CA2565630C (en) 2004-05-07 2013-05-28 Janssen Pharmaceutica N.V. Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors
JP5208505B2 (ja) 2004-08-30 2013-06-12 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ １１−ベータヒドロキシステロイドデヒドロゲナーゼ阻害剤としてのｎ−２アダマンタニル−２−フェノキシ−アセトアミド誘導体
DE602005017159D1 (de) 2004-08-30 2009-11-26 Janssen Pharmaceutica Nv Oxysteroid-dehydrogenase-inhibitoren
ES2334246T3 (es) 2004-08-30 2010-03-08 Janssen Pharmaceutica Nv Derivados triciclos de adamantilamida como inhibidores de la 11-beta-hidroxiesteroide-deshidrogenasa.
WO2010096503A1 (en) 2009-02-17 2010-08-26 Mcalister Technologies, Llc Electrolytic cell and method of use thereof
RU2489523C2 (ru) 2009-02-17 2013-08-10 МАКЭЛИСТЭР ТЕКНОЛОДЖИЗ, ЭлЭлСи Устройство и способ регулирования зародышеобразования во время электролиза
EP2398938B1 (de) 2009-02-17 2016-04-06 McAlister Technologies, LLC Vorrichtung und verfahren zur gaserfassung während einer elektrolyse
US8075750B2 (en) 2009-02-17 2011-12-13 Mcalister Technologies, Llc Electrolytic cell and method of use thereof
US9040012B2 (en) 2009-02-17 2015-05-26 Mcalister Technologies, Llc System and method for renewable resource production, for example, hydrogen production by microbial electrolysis, fermentation, and/or photosynthesis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3510492A (en) * 1968-05-13 1970-05-05 Upjohn Co 2-anilino and 2-anilinomethyl cycloalkylamines
US3647804A (en) * 1970-02-27 1972-03-07 Upjohn Co Cycloalkanecarboxamides
US3770825A (en) * 1970-12-07 1973-11-06 Yeda Res & Dev 2-substituted amino cycloalkylcarboxamides

Also Published As

Publication number Publication date
HU177576B (en) 1981-11-28
YU94982A (en) 1982-08-31
ATA395476A (de) 1978-11-15
CS217955B2 (en) 1983-02-25
FR2313023B1 (de) 1978-12-15
ATA612777A (de) 1978-04-15
AT346826B (de) 1978-11-27
DE2624290A1 (de) 1977-04-14
FR2313023A1 (fr) 1976-12-31
YU129376A (en) 1982-08-31

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
ELJ Ceased due to non-payment of the annual fee