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AT343123B - Verfahren zur herstellung von neuen piperazinderivaten - Google Patents

Verfahren zur herstellung von neuen piperazinderivaten

Info

Publication number
AT343123B
AT343123B AT848675A AT848675A AT343123B AT 343123 B AT343123 B AT 343123B AT 848675 A AT848675 A AT 848675A AT 848675 A AT848675 A AT 848675A AT 343123 B AT343123 B AT 343123B
Authority
AT
Austria
Prior art keywords
production
piperazine derivatives
new piperazine
new
derivatives
Prior art date
Application number
AT848675A
Other languages
English (en)
Other versions
ATA848675A (de
Original Assignee
Rhone Poulenc Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7436963A external-priority patent/FR2313060A1/fr
Priority claimed from FR7527160A external-priority patent/FR2322600A1/fr
Priority claimed from FR7527161A external-priority patent/FR2322601A1/fr
Priority claimed from FR7527162A external-priority patent/FR2322602A1/fr
Application filed by Rhone Poulenc Ind filed Critical Rhone Poulenc Ind
Priority to AT402077A priority Critical patent/AT343667B/de
Publication of ATA848675A publication Critical patent/ATA848675A/de
Application granted granted Critical
Publication of AT343123B publication Critical patent/AT343123B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT848675A 1974-11-07 1975-11-07 Verfahren zur herstellung von neuen piperazinderivaten AT343123B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT402077A AT343667B (de) 1975-11-07 1975-11-07 Verfahren zur herstellung von neuen piperazinderivaten

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR7436963A FR2313060A1 (fr) 1974-11-07 1974-11-07 Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent
FR7527160A FR2322600A1 (fr) 1975-09-04 1975-09-04 Nouveaux derives de la pyrrolo (3,4-b) pyrazine, leur preparation et les compositions qui les contiennent
FR7527161A FR2322601A1 (fr) 1975-09-04 1975-09-04 Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent
FR7527162A FR2322602A1 (fr) 1975-09-04 1975-09-04 Nouveaux derives de l'oxathiinno- et du dithiinnopyrrole, leur preparation et les compositions qui les contiennent

Publications (2)

Publication Number Publication Date
ATA848675A ATA848675A (de) 1977-09-15
AT343123B true AT343123B (de) 1978-05-10

Family

ID=27446274

Family Applications (2)

Application Number Title Priority Date Filing Date
AT848675A AT343123B (de) 1974-11-07 1975-11-07 Verfahren zur herstellung von neuen piperazinderivaten
AT401977A AT343666B (de) 1974-11-07 1977-06-07 Verfahren zur herstellung von neuen piperazinderivaten

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT401977A AT343666B (de) 1974-11-07 1977-06-07 Verfahren zur herstellung von neuen piperazinderivaten

Country Status (27)

Country Link
US (1) US4220646A (de)
JP (2) JPS5422996B2 (de)
AR (2) AR208414A1 (de)
AT (2) AT343123B (de)
AU (1) AU503200B2 (de)
BE (1) BE835325A (de)
CA (1) CA1057755A (de)
CH (1) CH609057A5 (de)
CS (2) CS231957B2 (de)
CY (1) CY1045A (de)
DD (1) DD122684A5 (de)
DE (1) DE2550111C2 (de)
DK (1) DK141098B (de)
FI (1) FI60707C (de)
GB (1) GB1468497A (de)
HK (1) HK19380A (de)
HU (1) HU173108B (de)
IE (1) IE41928B1 (de)
IL (1) IL48423A (de)
LU (1) LU73738A1 (de)
NL (1) NL177405C (de)
NO (1) NO143576C (de)
OA (1) OA05162A (de)
PL (1) PL101248B1 (de)
SE (1) SE407063B (de)
SU (2) SU673173A3 (de)
YU (2) YU39583B (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2371198A2 (fr) * 1976-11-22 1978-06-16 Rhone Poulenc Ind Nouveaux derives du dithiepinno (1,4)(2,3-c) pyrrole, leur preparation et les compositions qui les contiennent
US4533751A (en) * 1981-10-09 1985-08-06 Scm Corporation Preparation of 1,3-dienamines from myrcene and substituted myrcene
FR2525606A1 (fr) * 1982-04-22 1983-10-28 Rhone Poulenc Sante Nouveaux derives du dithiino (1,4) (2,3-c) pyrrole, leur preparation et les medicaments qui les contiennent
FR2607504B1 (fr) * 1986-12-02 1989-01-27 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607506B1 (fr) * 1986-12-02 1989-01-06 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2671800B1 (fr) * 1991-01-17 1993-03-12 Rhone Poulenc Rorer Sa Derive de la 5h-pyrrolo[3,4-b]pyrazine optiquement actif, sa preparation et les compositions pharmaceutiques qui le contiennent.
US5786357A (en) 1991-12-02 1998-07-28 Sepracor Inc. Methods and compositions for treating sleep disorders, convulsive seizures and other disorders using optically pure (+) zopiclone
HU214331B (hu) * 1992-06-17 1998-03-02 Gyógyszerkutató Intézet Kft. Eljárás piperazin- és homopiperazinszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
JPH08511022A (ja) * 1993-06-04 1996-11-19 ヘンケル コーポレーション 重合可能な化合物
US5565567A (en) * 1993-06-04 1996-10-15 Henkel Corporation. Polymerizable N,N'-substituted piperazine acrylamide compounds
US5922820A (en) * 1993-06-04 1999-07-13 Henkel Corporation Polymerizable compounds
MX9702125A (es) * 1994-09-23 1998-04-30 Arris Pharm Corp Composiciones y metodos para tratar condiciones inflamatorias mediadas por mastocitos.
US5663357A (en) * 1995-11-22 1997-09-02 Allergan Substituted heteroarylamides having retinoid-like biological activity
US5756742A (en) * 1995-12-22 1998-05-26 Henkel Corporation Polymerizable compounds
US6339086B1 (en) 1999-05-14 2002-01-15 Swpracor, Inc. Methods of making and using N-desmethylzopiclone
US7902179B2 (en) * 2001-04-26 2011-03-08 Ajinomoto Co., Inc. Heterocyclic compounds
ATE316530T1 (de) * 2002-03-29 2006-02-15 Indevus Pharmaceuticals Inc Verfahren zur herstellung von 2-(7-chloro-1,8-
WO2004037212A2 (en) * 2002-10-24 2004-05-06 Sepracor, Inc. Compositions comprising zopiclone derivatives and methods of making and using the same
US6909002B2 (en) * 2002-11-22 2005-06-21 Merck & Co., Inc. Method of preparing inhibitors of phosphodiesterase-4
AR042194A1 (es) * 2002-11-22 2005-06-15 Merck & Co Inc Metodo para preparar inhibidores de fosfodiesterasa - 4
CN1326856C (zh) * 2002-11-22 2007-07-18 麦克公司 制备磷酸二酯酶-4抑制剂的方法
DK1691811T3 (da) 2003-12-11 2014-10-20 Sunovion Pharmaceuticals Inc Kombination af et sedativ og en neurotransmittermodulator og fremgangsmåder til forbedring af søvnkvaliteten og behandling af depression
WO2005105061A2 (en) * 2004-04-14 2005-11-10 Indevus Pharmaceuticals, Inc. Transdermal patch
EP1904066B1 (de) 2005-07-06 2018-05-23 Sunovion Pharmaceuticals Inc. KOMBINATIONEN VON ESZOPICLON UND TRANS-4-(3,4-DICHLORPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE OR TRANS-4-(3,4-DICHLORPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPHTHALINAMIN ZUR BEHANDLUNG DER MENOPAUSE, Perimenopause UND VON KOGNITIVEN STÖRUNGEN
MX2008000249A (es) * 2005-07-06 2008-03-18 Sepracor Inc Combinaciones de eszopiclona y o-desmetilvenlafaxina y metodos de tratamiento de menopausia y trastornos del estado de animo, ansiedad y cognitivos.
CA2620333A1 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258357A3 (de) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenese mit Acetylcholinesterasehemmer
WO2007047978A2 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by pde inhibition
EP2314289A1 (de) 2005-10-31 2011-04-27 Braincells, Inc. Gaba-rezeptor-vermittelte modulation von neurogenese
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
CA2651813A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
EP2068872A1 (de) 2006-09-08 2009-06-17 Braincells, Inc. Kombinationen mit einem 4-acylaminopyridin-derivat
US20080305171A1 (en) * 2007-06-07 2008-12-11 Kristin Anne Arnold Pyrrolopyrazine, formulations, methods of manufacture, and methods of use there
CN100569775C (zh) * 2007-12-19 2009-12-16 齐鲁天和惠世制药有限公司 佐匹克隆的晶型转换的方法
EP2391354B1 (de) 2009-01-30 2019-11-27 Sunovion Pharmaceuticals Inc. Dragees von 6-(5-chloro-2-pyridyl) -5-[ (4-methyl-1-piperazinyl) carbonyloxy]-7-oxo-6, 7-dihydro-5h-pyrrolo [3,4-b] pyrazin und verfahren zu deren herstellung
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
CN110678497B (zh) * 2017-05-25 2022-09-16 信越化学工业株式会社 含有氟聚醚基的聚合物改性有机硅化合物、表面处理剂和物品
CN108129476A (zh) * 2017-11-27 2018-06-08 华中农业大学 一种杂环内酰胺衍生物及其用于作物病原菌杀菌剂的用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1312427A (fr) * 1961-04-12 1962-12-21 Science Union Et Compagnie Soc Nouveaux dérivés de la pipérazine et leurs préparations
FR2101081B1 (de) * 1970-08-19 1974-01-11 Rhone Poulenc Sa
BE790408A (fr) * 1971-10-22 1973-04-20 Rhone Poulenc Sa Nouveaux derives de la pyrrolo (3,4-b) pyridine, leur preparation et les compositions medicinales qui les
OA04285A (fr) * 1972-01-07 1979-12-31 Rhone Poulenc Sa Nouveaux dérivés de la pyrrolo (3,4-b) pyrazine et leur préparation.
BE793851A (fr) * 1972-01-10 1973-07-10 Rhone Poulenc Sa Nouveaux derives de l'isoindoline, leur preparation et les compositions medicinales qui les contiennent
AR207555A1 (es) * 1972-12-04 1976-10-15 Procedimiento para preparar aril-6-piperazinocarboniloxi-5 oxo-7 tetrahidro-2,3,6,7 ditiino(1,4)(2,3-c)pirroles
OA04700A (fr) * 1973-05-15 1980-07-31 Rhone Poulenc Sa Nouveaux dérivés de la naphtyridine et leur procédé de préparation.

Also Published As

Publication number Publication date
DE2550111A1 (de) 1976-05-13
GB1468497A (en) 1977-03-30
DK141098C (de) 1980-07-07
AR208414A1 (es) 1976-12-27
AR208800A1 (es) 1977-02-28
YU192182A (en) 1983-01-21
SU604496A3 (ru) 1978-04-25
JPS5498790A (en) 1979-08-03
BE835325A (fr) 1976-05-06
DD122684A5 (de) 1976-10-20
IE41928B1 (en) 1980-04-23
CY1045A (en) 1980-08-01
NO143576C (no) 1981-03-11
IE41928L (en) 1976-05-07
YU39583B (en) 1985-03-20
AT343666B (de) 1978-06-12
FI753127A (de) 1976-05-08
CA1057755A (fr) 1979-07-03
CS231957B2 (en) 1985-01-16
HU173108B (hu) 1979-02-28
CS751075A2 (en) 1984-01-16
SU673173A3 (ru) 1979-07-05
FI60707C (fi) 1982-03-10
LU73738A1 (de) 1976-09-06
DK141098B (da) 1980-01-14
NO753713L (de) 1976-05-10
YU40087B (en) 1985-06-30
ATA848675A (de) 1977-09-15
SE7512477L (sv) 1976-05-10
ATA401977A (de) 1977-10-15
CS598377A2 (en) 1984-01-16
AU8633175A (en) 1977-05-12
NL7512732A (nl) 1976-05-11
NL177405B (nl) 1985-04-16
FI60707B (fi) 1981-11-30
CH609057A5 (de) 1979-02-15
IL48423A0 (en) 1976-01-30
JPS5422996B2 (de) 1979-08-10
IL48423A (en) 1979-03-12
YU281575A (en) 1983-01-21
PL101248B1 (pl) 1978-12-30
DK499275A (de) 1976-05-08
AU503200B2 (en) 1979-08-30
JPS558508B2 (de) 1980-03-04
NL177405C (nl) 1985-09-16
US4220646A (en) 1980-09-02
CS231958B2 (en) 1985-01-16
SE407063B (sv) 1979-03-12
DE2550111C2 (de) 1983-09-15
OA05162A (fr) 1981-01-31
JPS5170776A (de) 1976-06-18
NO143576B (no) 1980-12-01
HK19380A (en) 1980-04-18

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