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AT339281B - PROCESS FOR THE PREPARATION OF NEW 1-ARYLOXY-2-HYDROXY-4-SEC.AMINOBUTANES AND THEIR NON-TOXIC ACID ADDITION SALTS - Google Patents

PROCESS FOR THE PREPARATION OF NEW 1-ARYLOXY-2-HYDROXY-4-SEC.AMINOBUTANES AND THEIR NON-TOXIC ACID ADDITION SALTS

Info

Publication number
AT339281B
AT339281B AT114075A AT114075A AT339281B AT 339281 B AT339281 B AT 339281B AT 114075 A AT114075 A AT 114075A AT 114075 A AT114075 A AT 114075A AT 339281 B AT339281 B AT 339281B
Authority
AT
Austria
Prior art keywords
aminobutanes
aryloxy
sec
hydroxy
preparation
Prior art date
Application number
AT114075A
Other languages
German (de)
Other versions
ATA114075A (en
Inventor
Kalman Dr Chem Ing Harsanyi
Dezso Dr Chem Ing Korbonits
Erzsebet Dr Molnar
Jozsef Dr Szegi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Priority to AT729676A priority Critical patent/AT340899B/en
Publication of ATA114075A publication Critical patent/ATA114075A/en
Application granted granted Critical
Publication of AT339281B publication Critical patent/AT339281B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT114075A 1974-02-20 1975-02-17 PROCESS FOR THE PREPARATION OF NEW 1-ARYLOXY-2-HYDROXY-4-SEC.AMINOBUTANES AND THEIR NON-TOXIC ACID ADDITION SALTS AT339281B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT729676A AT340899B (en) 1974-02-20 1976-10-01 PROCESS FOR THE PREPARATION OF NEW 1-ARYLOXY-2-HYDROXY-4-SEC.AMINOBUTANES AND THEIR NON-TOXIC ACID ADDITION SALTS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI1449A HU169464B (en) 1974-02-20 1974-02-20

Publications (2)

Publication Number Publication Date
ATA114075A ATA114075A (en) 1977-02-15
AT339281B true AT339281B (en) 1977-10-10

Family

ID=10994508

Family Applications (1)

Application Number Title Priority Date Filing Date
AT114075A AT339281B (en) 1974-02-20 1975-02-17 PROCESS FOR THE PREPARATION OF NEW 1-ARYLOXY-2-HYDROXY-4-SEC.AMINOBUTANES AND THEIR NON-TOXIC ACID ADDITION SALTS

Country Status (22)

Country Link
JP (1) JPS5929063B2 (en)
AT (1) AT339281B (en)
BE (1) BE825745A (en)
BG (2) BG26367A4 (en)
CA (1) CA1074338A (en)
CH (1) CH619684A5 (en)
CS (1) CS199578B2 (en)
DD (1) DD119414A5 (en)
DE (1) DE2506355C2 (en)
DK (1) DK141935B (en)
ES (2) ES434784A1 (en)
FI (1) FI61304C (en)
FR (1) FR2261001B1 (en)
GB (1) GB1457086A (en)
HU (1) HU169464B (en)
IL (1) IL46634A (en)
NL (1) NL182698C (en)
NO (1) NO141754C (en)
PL (2) PL99025B1 (en)
SE (1) SE433935B (en)
SU (1) SU1025327A3 (en)
YU (2) YU36916B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48309A (en) * 1974-10-25 1980-01-31 Robins Co Inc A H 1-aryloxy-4-amino-2-butanols and pharmaceutical compositions containing them
EP0097000B1 (en) * 1982-06-10 1987-09-09 Beecham Wuelfing GmbH & Co KG Amine derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1245148A (en) * 1968-11-18 1971-09-08 Pfizer Ltd Propanolamine derivatives
SE368197B (en) * 1968-11-18 1974-06-24 Pfizer
SE384853B (en) * 1972-04-04 1976-05-24 Haessle Ab PROCEDURE FOR THE PREPARATION OF NEW AMINES
AT304472B (en) * 1969-09-24 1973-01-10 Ici Ltd Process for the preparation of new substituted 1-phenoxy-2-hydroxy-3-alkylaminopropanes and their acid addition salts

Also Published As

Publication number Publication date
FR2261001A1 (en) 1975-09-12
BG26367A4 (en) 1979-03-15
PL99025B1 (en) 1978-06-30
NL182698C (en) 1988-05-02
BE825745A (en) 1975-06-16
NL7501951A (en) 1975-08-22
IL46634A (en) 1979-01-31
IL46634A0 (en) 1975-04-25
DK141935C (en) 1980-12-08
DK60875A (en) 1975-10-20
FI61304B (en) 1982-03-31
YU167681A (en) 1983-04-27
CH619684A5 (en) 1980-10-15
YU36916B (en) 1984-08-31
DE2506355C2 (en) 1983-10-06
CS199578B2 (en) 1980-07-31
NO141754C (en) 1980-05-07
FR2261001B1 (en) 1978-07-21
ES434784A1 (en) 1977-03-16
YU37116B (en) 1984-08-31
NO141754B (en) 1980-01-28
JPS50117728A (en) 1975-09-16
CA1074338A (en) 1980-03-25
GB1457086A (en) 1976-12-01
SE433935B (en) 1984-06-25
SU1025327A3 (en) 1983-06-23
NO750566L (en) 1975-08-21
HU169464B (en) 1976-11-28
ATA114075A (en) 1977-02-15
FI750443A (en) 1975-08-21
ES453326A1 (en) 1977-11-16
SE7501801L (en) 1975-08-21
YU37375A (en) 1982-06-18
JPS5929063B2 (en) 1984-07-18
DK141935B (en) 1980-07-21
DD119414A5 (en) 1976-04-20
PL99023B1 (en) 1978-06-30
DE2506355A1 (en) 1975-08-21
FI61304C (en) 1982-07-12
BG26366A3 (en) 1979-03-15

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Legal Events

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