AT329200B - Verfahren zur herstellung von neuen 2- (heteroaryl-methyl) -5,9beta-dialkyl -6,7-benzomorphanen - Google Patents

Verfahren zur herstellung von neuen 2- (heteroaryl-methyl) -5,9beta-dialkyl -6,7-benzomorphanen

Info

Publication number: AT329200B
Authority: AT; Austria
Prior art keywords: benzomorphanes; 9beta; dialkyl; heteroaryl; methyl
Prior art date: 1972-06-19

Application number

AT489974*7A

Other languages

English (en)

Other versions

ATA489974A (de

Original Assignee

Boehringer Sohn Ingelheim

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-06-19

Filing date

1973-06-06

Publication date

1976-04-26

1973-06-06 Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim

1975-07-15 Publication of ATA489974A publication Critical patent/ATA489974A/de

1976-04-26 Application granted granted Critical

1976-04-26 Publication of AT329200B publication Critical patent/AT329200B/de

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Steroid Compounds (AREA)

AT489974*7A 1972-06-19 1973-06-06 Verfahren zur herstellung von neuen 2- (heteroaryl-methyl) -5,9beta-dialkyl -6,7-benzomorphanen AT329200B (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2229695A DE2229695A1 (de)	1972-06-19	1972-06-19	2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung

Publications (2)

Publication Number	Publication Date
ATA489974A ATA489974A (de)	1975-07-15
AT329200B true AT329200B (de)	1976-04-26

Family

ID=5848060

Family Applications (6)

Application Number	Title	Priority Date	Filing Date
AT489874*7A AT329199B (de)	1972-06-19	1973-06-06	Verfahren zur herstellung von neuen 2-(heteroaryl-methyl)-5,9beta-dialkyl-6,7-benzomorphanen
AT489474*7A AT328627B (de)	1972-06-19	1973-06-06	Verfahren zur herstellung von neuen 2- (thienylmethyl)-5,9beta-dialkyl-6,7-benzomorphanen
AT494373A AT325218B (de)	1972-06-19	1973-06-06	Verfahren zur herstellung von neuen 2-(heteroarylmethyl)-5,9beta-dialkyl-6,7-benzomorphanen
AT489774*7A AT328628B (de)	1972-06-19	1973-06-06	Verfahren zur herstellung von neuen 2- (heteroarylmethyl) -5,9beta-dialkyl-6,7-benzomorphanen
AT490074*7A AT328629B (de)	1972-06-19	1973-06-06	Verfahren zur herstellung von neuen 2- (furylmethyl) -5,9beta-dialkyl-6,7-benzomorphanen
AT489974*7A AT329200B (de)	1972-06-19	1973-06-06	Verfahren zur herstellung von neuen 2- (heteroaryl-methyl) -5,9beta-dialkyl -6,7-benzomorphanen

Family Applications Before (5)

Application Number	Title	Priority Date	Filing Date
AT489874*7A AT329199B (de)	1972-06-19	1973-06-06	Verfahren zur herstellung von neuen 2-(heteroaryl-methyl)-5,9beta-dialkyl-6,7-benzomorphanen
AT489474*7A AT328627B (de)	1972-06-19	1973-06-06	Verfahren zur herstellung von neuen 2- (thienylmethyl)-5,9beta-dialkyl-6,7-benzomorphanen
AT494373A AT325218B (de)	1972-06-19	1973-06-06	Verfahren zur herstellung von neuen 2-(heteroarylmethyl)-5,9beta-dialkyl-6,7-benzomorphanen
AT489774*7A AT328628B (de)	1972-06-19	1973-06-06	Verfahren zur herstellung von neuen 2- (heteroarylmethyl) -5,9beta-dialkyl-6,7-benzomorphanen
AT490074*7A AT328629B (de)	1972-06-19	1973-06-06	Verfahren zur herstellung von neuen 2- (furylmethyl) -5,9beta-dialkyl-6,7-benzomorphanen

Country Status (13)

Country	Link
US (1)	US3931194A (de)
JP (1)	JPS5711908B2 (de)
AT (6)	AT329199B (de)
BE (1)	BE801079A (de)
CH (9)	CH589649A5 (de)
DE (1)	DE2229695A1 (de)
DK (1)	DK136904C (de)
ES (8)	ES416037A1 (de)
FR (1)	FR2189056B1 (de)
GB (1)	GB1433817A (de)
NL (1)	NL7308483A (de)
NO (1)	NO137694C (de)
SE (1)	SE405121B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2437610A1 (de) *	1974-08-05	1976-02-26	Boehringer Sohn Ingelheim	Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
GB1575009A (en) *	1976-06-21	1980-09-17	Acf Chemiefarma Nv	6,7-benzomorphan derivatives
JPS63177704A (ja) *	1987-01-16	1988-07-21	松山株式会社	農作業機連結装置
EP2183228B1 (de)	2007-07-26	2014-08-20	Vitae Pharmaceuticals, Inc.	ZYKLISCHE 11ß-HYDROXYSTEROID-DEHYDROGENASE-1-HEMMER
US8859580B2 (en)	2007-11-16	2014-10-14	Boehringer Ingelheim International Gmbh	Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
CA2708303A1 (en)	2007-12-11	2009-06-18	Vitae Pharmaceuticals, Inc.	Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
TW200934490A (en)	2008-01-07	2009-08-16	Vitae Pharmaceuticals Inc	Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
WO2009094169A1 (en)	2008-01-24	2009-07-30	Vitae Pharmaceuticals, Inc.	Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009100872A1 (en) *	2008-02-12	2009-08-20	Boehringer Ingelheim International Gmbh	Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
CA2715290A1 (en)	2008-02-15	2009-08-20	Vitae Pharmaceuticals, Inc.	Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2291370B1 (de)	2008-05-01	2013-11-27	Vitae Pharmaceuticals, Inc.	Cyclische inhibitoren von 11beta-hydroxysteroiddehydrogenase 1
TW200946520A (en)	2008-05-01	2009-11-16	Vitae Pharmaceuticals Inc	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2723039A1 (en)	2008-05-01	2009-11-05	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2288596B1 (de)	2008-05-13	2016-11-30	Boehringer Ingelheim International GmbH	Alizyklische carboxylsäurederivate von benzomorphanen, entsprechende gerüste, medikamente mit solchen verbindungen und ihre verwendung
KR20110050459A (ko)	2008-07-25	2011-05-13	비타이 파마슈티컬즈, 인코포레이티드	11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
WO2010010157A2 (en)	2008-07-25	2010-01-28	Boehringer Ingelheim International Gmbh	INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
MA33216B1 (fr)	2009-04-30	2012-04-02	Boehringer Ingelheim Int	Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
JP5656986B2 (ja)	2009-06-11	2015-01-21	ヴァイティーファーマシューティカルズ，インコーポレイテッド	１，３−オキサジナン−２−オン構造に基づく１１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤
AR078887A1 (es) *	2009-11-06	2011-12-07	Boehringer Ingelheim Int	Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
US8933072B2 (en)	2010-06-16	2015-01-13	Vitae Pharmaceuticals, Inc.	Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh)	2010-11-05	2016-06-11	百靈佳殷格翰國際股份有限公司	六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
EP2744783A1 (de)	2011-08-17	2014-06-25	Boehringer Ingelheim International GmbH	Indenopyridinderivate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE582575A (de) *	1958-09-22
FR1281227A (fr) *	1958-09-22	1962-01-12	Smith Kline French Lab	Perfectionnements apportés aux procédés pour la préparation de dérivés d'aralcoylbenzomorphane
CS166801B2 (de) *	1971-02-08	1976-03-29	Boehringer Sohn Ingelheim
SE392895B (sv) *	1971-08-24	1977-04-25	Sumitomo Chemical Co	Forfarande for framstellning av bensomorfanderivat och deras salter

1972
- 1972-06-19 DE DE2229695A patent/DE2229695A1/de not_active Withdrawn
1973
- 1973-06-05 US US05/367,114 patent/US3931194A/en not_active Expired - Lifetime
- 1973-06-06 AT AT489874*7A patent/AT329199B/de not_active IP Right Cessation
- 1973-06-06 AT AT489474*7A patent/AT328627B/de not_active IP Right Cessation
- 1973-06-06 AT AT494373A patent/AT325218B/de not_active IP Right Cessation
- 1973-06-06 AT AT489774*7A patent/AT328628B/de not_active IP Right Cessation
- 1973-06-06 AT AT490074*7A patent/AT328629B/de not_active IP Right Cessation
- 1973-06-06 AT AT489974*7A patent/AT329200B/de not_active IP Right Cessation
- 1973-06-14 CH CH1041476A patent/CH589649A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH864373A patent/CH583227A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1040976A patent/CH583229A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041076A patent/CH583230A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1040876A patent/CH583228A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041276A patent/CH589648A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041576A patent/CH583231A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041176A patent/CH582697A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041376A patent/CH582698A5/xx not_active IP Right Cessation
- 1973-06-18 BE BE132406A patent/BE801079A/xx unknown
- 1973-06-18 NO NO2518/73A patent/NO137694C/no unknown
- 1973-06-18 ES ES416037A patent/ES416037A1/es not_active Expired
- 1973-06-18 DK DK336173A patent/DK136904C/da active
- 1973-06-18 SE SE7308564A patent/SE405121B/xx unknown
- 1973-06-18 GB GB2886973A patent/GB1433817A/en not_active Expired
- 1973-06-18 JP JP6863473A patent/JPS5711908B2/ja not_active Expired
- 1973-06-19 NL NL7308483A patent/NL7308483A/xx not_active Application Discontinuation
- 1973-06-19 FR FR7322249A patent/FR2189056B1/fr not_active Expired
1974
- 1974-10-30 ES ES431510A patent/ES431510A1/es not_active Expired
- 1974-10-30 ES ES431514A patent/ES431514A1/es not_active Expired
- 1974-10-30 ES ES431513A patent/ES431513A1/es not_active Expired
- 1974-10-30 ES ES431511A patent/ES431511A1/es not_active Expired
- 1974-10-30 ES ES431515A patent/ES431515A1/es not_active Expired
- 1974-10-30 ES ES431512A patent/ES431512A1/es not_active Expired
- 1974-10-30 ES ES0431516A patent/ES431516A1/es not_active Expired

Also Published As

Publication number	Publication date
FR2189056B1 (de)	1976-10-22
ES431513A1 (es)	1976-11-01
CH589648A5 (de)	1977-07-15
ATA489874A (de)	1975-07-15
ES431511A1 (es)	1976-11-01
ES431512A1 (es)	1976-11-01
NO137694C (no)	1978-04-05
AT328628B (de)	1976-03-25
ES431515A1 (es)	1976-11-01
NO137694B (no)	1977-12-27
DK136904C (da)	1978-06-26
DE2229695A1 (de)	1974-01-31
CH583229A5 (de)	1976-12-31
ES416037A1 (es)	1976-02-16
GB1433817A (en)	1976-04-28
DK136904B (da)	1977-12-12
FR2189056A1 (de)	1974-01-25
ES431516A1 (es)	1976-11-16
JPS4961170A (de)	1974-06-13
CH583227A5 (de)	1976-12-31
AT325218B (de)	1975-10-10
AT328627B (de)	1976-03-25
JPS5711908B2 (de)	1982-03-08
US3931194A (en)	1976-01-06
CH589649A5 (de)	1977-07-15
SE405121B (sv)	1978-11-20
BE801079A (fr)	1973-12-18
CH583228A5 (de)	1976-12-31
ATA489974A (de)	1975-07-15
ES431510A1 (es)	1976-11-01
CH582698A5 (de)	1976-12-15
CH583231A5 (de)	1976-12-31
ATA489474A (de)	1975-06-15
ATA490074A (de)	1975-06-15
AT328629B (de)	1976-03-25
AU5704673A (en)	1974-12-19
AT329199B (de)	1976-04-26
NL7308483A (de)	1973-12-21
ES431514A1 (es)	1976-11-01
CH582697A5 (de)	1976-12-15
CH583230A5 (de)	1976-12-31
ATA489774A (de)	1975-06-15

Publication	Publication Date	Title
AT340590B (de)	1977-12-27	Verfahren zur herstellung von neuen 7-acylaminocephalosporinderivaten
AT329199B (de)	1976-04-26	Verfahren zur herstellung von neuen 2-(heteroaryl-methyl)-5,9beta-dialkyl-6,7-benzomorphanen
AT331258B (de)	1976-08-10	Verfahren zur herstellung von neuen 1,2,3-oxathiazin-4-onen
AT329076B (de)	1976-04-26	Verfahren zur herstellung von neuen 1-aminouracilen
AT331791B (de)	1976-08-25	Verfahren zur herstellung von neuen 2-oxazolinderivaten
AT324312B (de)	1975-08-25	Verfahren zur herstellung von neuen trifluormethylsalicylaniliden
AT315147B (de)	1974-05-10	Verfahren zur Herstellung von neuen N<1>-Alkoxyalkyliden-3,5-dinitro-sulfanilamiden
AT325219B (de)	1975-10-10	Verfahren zur herstellung von neuen n-(heteroaryl-methyl)-6, 14-endoätheno-7alpha-hydroxyalkyltetrahydro-nororipavinen und -thebainen
AT324333B (de)	1975-08-25	Verfahren zur herstellung von neuen substituierten 5-chromanolen
AT330766B (de)	1976-07-26	Verfahren zur herstellung von neuen sulfamoylphenylimidazolidinonderivaten
AT323750B (de)	1975-07-25	Verfahren zur herstellung von neuen nitroimidazolyl-triazolc-pyridazinen
AT326115B (de)	1975-11-25	Verfahren zur herstellung von neuen 5-acylpyrrolderivaten
ATA429175A (de)	1975-09-15	Verfahren zur herstellung von neuen 2- (heteroaryl-methyl) -5,9beta-dialkyl -6,7- benzomorphanen
ATA489574A (de)	1975-09-15	Verfahren zur herstellung von neuen 2- (heteroaryl-methyl) -5,9beta-dialkyl -6,7- benzomorphanen
AT326837B (de)	1975-12-29	Verfahren zur herstellung von neuen 2,2'-anhydro-1-beta-d-arabinofuranosyl-5-fluorcytosin-hydrofluorid, -hydrochlorid oder -hydrobromid
AT316747B (de)	1974-07-25	Verfahren zur Herstellung von neuen Alkyl-7-deoxy-7-mercaptoalkylthio-α-thiolincosaminiden
AT315166B (de)	1974-05-10	Verfahren zur Herstellung von neuen 2-Acyl-5-nitrothiazolen
AT332400B (de)	1976-09-27	Verfahren zur herstellung von neuen 4-phenylaminopyridinderivaten
ATA489674A (de)	1978-04-15	Verfahren zur herstellung von neuen 2- (heteroarylmethyl)-5,9beta-dialkyl-6,7-benzomorphanen
AT323714B (de)	1975-07-25	Verfahren zur herstellung von neuen 6,9-dioxo-8-hydroxy-2-suestituierten-bicyclo-(3,3,1)-non-7-en-3-olen
AT324347B (de)	1975-08-25	Verfahren zur herstellung von neuen substituierten azetidin-2-onen
AT329569B (de)	1976-05-25	Verfahren zur herstellung von neuen 2,4-benzoxazepin-derivaten
AT329059B (de)	1976-04-26	Verfahren zur herstellung von neuen tetrahydroisochinolindionderivaten
AT330182B (de)	1976-06-25	Verfahren zur herstellung von neuen tetrahydroisochinolindionderivaten
ATA226175A (de)	1975-09-15	Verfahren zur herstellung von neuen tetrahydroisochinolindionderivaten

Legal Events

Date	Code	Title	Description
1983-04-15	ELJ	Ceased due to non-payment of the annual fee