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AR126205A2 - Métodos de uso de linfocitos infiltrantes de tumor en melanoma doble refractario - Google Patents

Métodos de uso de linfocitos infiltrantes de tumor en melanoma doble refractario

Info

Publication number
AR126205A2
AR126205A2 ARP220101639A ARP220101639A AR126205A2 AR 126205 A2 AR126205 A2 AR 126205A2 AR P220101639 A ARP220101639 A AR P220101639A AR P220101639 A ARP220101639 A AR P220101639A AR 126205 A2 AR126205 A2 AR 126205A2
Authority
AR
Argentina
Prior art keywords
tumor infiltrating
infiltrating lymphocytes
methods
refractory melanoma
double refractory
Prior art date
Application number
ARP220101639A
Other languages
English (en)
Inventor
Maria Fardis
Original Assignee
Iovance Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iovance Biotherapeutics Inc filed Critical Iovance Biotherapeutics Inc
Publication of AR126205A2 publication Critical patent/AR126205A2/es

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/57—Skin; melanoma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/521—Chemokines
    • G01N2333/522—Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4 or KC

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Abstract

Reivindicación 1: Un método para tratar el melanoma metastásico doble refractario en un paciente que lo necesite, en donde el método comprende administrar al paciente una población terapéuticamente efectiva de linfocitos infiltrantes de tumor (TIL).
ARP220101639A 2017-06-05 2022-06-22 Métodos de uso de linfocitos infiltrantes de tumor en melanoma doble refractario AR126205A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762515257P 2017-06-05 2017-06-05

Publications (1)

Publication Number Publication Date
AR126205A2 true AR126205A2 (es) 2023-09-27

Family

ID=62791820

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP180101508A AR112072A1 (es) 2017-06-05 2018-06-05 Métodos de uso de linfocitos infiltrantes de tumor en melanoma doble refractario
ARP220101639A AR126205A2 (es) 2017-06-05 2022-06-22 Métodos de uso de linfocitos infiltrantes de tumor en melanoma doble refractario

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP180101508A AR112072A1 (es) 2017-06-05 2018-06-05 Métodos de uso de linfocitos infiltrantes de tumor en melanoma doble refractario

Country Status (7)

Country Link
US (4) US11819517B2 (es)
EP (1) EP3635097A1 (es)
JP (2) JP2020522516A (es)
AR (2) AR112072A1 (es)
CA (1) CA3065532A1 (es)
TW (1) TW201919662A (es)
WO (2) WO2018226714A1 (es)

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CA3065532A1 (en) 2018-12-13
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