AR108210A1 - THREE-SPECIFIC AND / OR TRIVAL UNION PROTEINS - Google Patents
THREE-SPECIFIC AND / OR TRIVAL UNION PROTEINSInfo
- Publication number
- AR108210A1 AR108210A1 ARP170100972A ARP170100972A AR108210A1 AR 108210 A1 AR108210 A1 AR 108210A1 AR P170100972 A ARP170100972 A AR P170100972A AR P170100972 A ARP170100972 A AR P170100972A AR 108210 A1 AR108210 A1 AR 108210A1
- Authority
- AR
- Argentina
- Prior art keywords
- proteins
- trival
- specific
- binding
- polypeptides
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 102000014914 Carrier Proteins Human genes 0.000 abstract 5
- 108091008324 binding proteins Proteins 0.000 abstract 5
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000009977 dual effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
La descripción proporciona proteínas de unión triespecíficas y/o trivalentes que comprenden cuatro cadenas de polipéptidos que forman tres sitios de unión con antígenos que específicamente unen una o varias proteínas blanco, en donde un primer par de polipéptidos que forman la proteína de unión posee dominios variables duales que tienen una orientación cruzada y en donde un segundo par de polipéptidos que forman la proteína de unión posee un dominio variable simple. La descripción también proporciona métodos para preparar proteínas de unión triespecíficas y/o trivalentes y usos de tales proteínas de unión.The description provides trispecific and / or trivalent binding proteins comprising four polypeptide chains that form three binding sites with antigens that specifically bind one or more white proteins, wherein a first pair of polypeptides that form the binding protein has variable domains. Duals that have a cross-orientation and where a second pair of polypeptides that form the binding protein has a simple variable domain. The description also provides methods for preparing triespecific and / or trivalent binding proteins and uses of such binding proteins.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662322036P | 2016-04-13 | 2016-04-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR108210A1 true AR108210A1 (en) | 2018-07-25 |
Family
ID=63036921
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP170100972A AR108210A1 (en) | 2016-04-13 | 2017-04-17 | THREE-SPECIFIC AND / OR TRIVAL UNION PROTEINS |
Country Status (1)
| Country | Link |
|---|---|
| AR (1) | AR108210A1 (en) |
-
2017
- 2017-04-17 AR ARP170100972A patent/AR108210A1/en unknown
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