AR074974A1 - A TOPIC ECTOPARASITICIDE COMPOSITION - Google Patents
A TOPIC ECTOPARASITICIDE COMPOSITIONInfo
- Publication number
- AR074974A1 AR074974A1 ARP090103425A ARP090103425A AR074974A1 AR 074974 A1 AR074974 A1 AR 074974A1 AR P090103425 A ARP090103425 A AR P090103425A AR P090103425 A ARP090103425 A AR P090103425A AR 074974 A1 AR074974 A1 AR 074974A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition according
- insecticide
- prodrug
- pharmaceutically
- acceptable derivative
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- RFEJUZJILGIRHQ-XRIOVQLTSA-N 2,3-dihydroxybutanedioic acid;3-[(2s)-1-methylpyrrolidin-2-yl]pyridine Chemical compound OC(=O)C(O)C(O)C(O)=O.OC(=O)C(O)C(O)C(O)=O.CN1CCC[C@H]1C1=CC=CN=C1 RFEJUZJILGIRHQ-XRIOVQLTSA-N 0.000 title 1
- 239000013057 ectoparasiticide Substances 0.000 title 1
- 239000002917 insecticide Substances 0.000 abstract 4
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 3
- 239000000651 prodrug Substances 0.000 abstract 3
- 229940002612 prodrug Drugs 0.000 abstract 3
- OEDUIFSDODUDRK-UHFFFAOYSA-N 5-phenyl-1h-pyrazole Chemical compound N1N=CC=C1C1=CC=CC=C1 OEDUIFSDODUDRK-UHFFFAOYSA-N 0.000 abstract 2
- 241000238631 Hexapoda Species 0.000 abstract 2
- -1 chloronicotinyl Chemical group 0.000 abstract 2
- 239000003630 growth substance Substances 0.000 abstract 2
- HOKKPVIRMVDYPB-UVTDQMKNSA-N (Z)-thiacloprid Chemical compound C1=NC(Cl)=CC=C1CN1C(=N/C#N)/SCC1 HOKKPVIRMVDYPB-UVTDQMKNSA-N 0.000 abstract 1
- ZOCSXAVNDGMNBV-UHFFFAOYSA-N 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile Chemical group NC1=C(S(=O)C(F)(F)F)C(C#N)=NN1C1=C(Cl)C=C(C(F)(F)F)C=C1Cl ZOCSXAVNDGMNBV-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000005899 Fipronil Substances 0.000 abstract 1
- 239000005906 Imidacloprid Substances 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000005940 Thiacloprid Substances 0.000 abstract 1
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 244000078703 ectoparasite Species 0.000 abstract 1
- 230000001984 ectoparasiticidal effect Effects 0.000 abstract 1
- 229940013764 fipronil Drugs 0.000 abstract 1
- 229940056881 imidacloprid Drugs 0.000 abstract 1
- YWTYJOPNNQFBPC-UHFFFAOYSA-N imidacloprid Chemical group [O-][N+](=O)\N=C1/NCCN1CC1=CC=C(Cl)N=C1 YWTYJOPNNQFBPC-UHFFFAOYSA-N 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000035800 maturation Effects 0.000 abstract 1
- 229950003442 methoprene Drugs 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N49/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds containing the group, wherein m+n>=1, both X together may also mean —Y— or a direct carbon-to-carbon bond, and the carbon atoms marked with an asterisk are not part of any ring system other than that which may be formed by the atoms X, the carbon atoms in square brackets being part of any acyclic or cyclic structure, or the group, wherein A means a carbon atom or Y, n>=0, and not more than one of these carbon atoms being a member of the same ring system, e.g. juvenile insect hormones or mimics thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Insects & Arthropods (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Una composicion ectoparasiticida topica que comprende: (i) un regulador del crecimiento de los insectos y/o un insecticida de fenil-pirazol y/o un insecticida de cloronicotinilo; (ii) glicoléter; y (iii) un alcohol C1-4 y/o DMSO. Reivindicacion 7: La composicion de acuerdo con la reivindicacion 6, caracterizada porque el regulador del crecimiento de los insectos es s-metopreno o un derivado o profármaco farmacéutica o veterinariamente aceptable del mismo. Reivindicacion 8: La composicion de acuerdo con una cualquiera de las reivindicaciones precedentes, caracterizada porque el insecticida de fenil-pirazol es fipronil o un derivado o profármaco farmacéutica o veterinariamente aceptable del mismo. Reivindicacion 12: La composicion de acuerdo con una cualquiera de las reivindicaciones precedentes, caracterizada porque el insecticida de cloronicotinilo se selecciona entre imidacloprid y/o tiacloprid o un derivado o profármaco farmacéutica o veterinariamente aceptable del mismo. Reivindicacion 35: El uso de una composicion de acuerdo con la definicion de una cualquiera de las reivindicaciones 1 a 31, en Ia fabricacion de un medicamento para la reduccion o la inhibicion de la maduracion de ectoparásitos jovenes de la piel de un animal.A topical ectoparasiticidal composition comprising: (i) an insect growth regulator and / or a phenyl-pyrazole insecticide and / or a chloronicotinyl insecticide; (ii) glycol ether; and (iii) a C1-4 alcohol and / or DMSO. Claim 7: The composition according to claim 6, characterized in that the insect growth regulator is s-methoprene or a pharmaceutically or veterinarily acceptable derivative or prodrug thereof. Claim 8: The composition according to any one of the preceding claims, characterized in that the phenyl-pyrazole insecticide is fipronil or a pharmaceutically or veterinarily acceptable derivative or prodrug thereof. Claim 12: The composition according to any one of the preceding claims, characterized in that the chloronicotinyl insecticide is selected from imidacloprid and / or thiacloprid or a pharmaceutically or veterinarily acceptable derivative or prodrug thereof. Claim 35: The use of a composition according to the definition of any one of claims 1 to 31, in the manufacture of a medicament for the reduction or inhibition of the maturation of young ectoparasites from the skin of an animal.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0816306A GB2464449B (en) | 2008-09-05 | 2008-09-05 | A topical ectoparasticide composition |
Publications (1)
Publication Number | Publication Date |
---|---|
AR074974A1 true AR074974A1 (en) | 2011-03-02 |
Family
ID=39888916
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP090103425A AR074974A1 (en) | 2008-09-05 | 2009-09-07 | A TOPIC ECTOPARASITICIDE COMPOSITION |
Country Status (3)
Country | Link |
---|---|
AR (1) | AR074974A1 (en) |
GB (1) | GB2464449B (en) |
WO (1) | WO2010026370A1 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2010212672B2 (en) * | 2009-02-16 | 2015-04-09 | Cipla Limited | Topical composition |
EP2416663A2 (en) | 2009-03-18 | 2012-02-15 | Martin Benedict George Donnelly | Parasiticidal formulation |
CN102651967B (en) * | 2010-04-01 | 2014-09-10 | 龙灯农业化工国际有限公司 | Insecticide composition and method of controlling insects using same |
UA108641C2 (en) | 2010-04-02 | 2015-05-25 | PARASITICID COMPOSITION CONTAINING FOUR ACTIVE AGENTS AND METHOD OF APPLICATION | |
RU2014103005A (en) | 2011-06-30 | 2015-08-10 | Ханзен-Аб Гмбх | ANIMAL PARASITIS AGENT |
US9034912B1 (en) * | 2012-03-23 | 2015-05-19 | Jugal K. Taneja | Veterinary composition and method |
US8653128B1 (en) * | 2012-03-23 | 2014-02-18 | Jugal K. Taneja | Veterinary composition and method |
GB201520724D0 (en) * | 2015-11-24 | 2016-01-06 | Merial Inc | Veterinary formulations |
CN110664806B (en) * | 2019-10-17 | 2023-02-28 | 广东省农业科学院动物卫生研究所 | Fipronil and methoprene dihydric alcohol plastid and preparation method and application thereof |
CN115317498B (en) * | 2022-08-26 | 2023-12-19 | 佛山市南海东方澳龙制药有限公司 | Compound drop for treating canine and feline parasites and fungal skin diseases and preparation method thereof |
CN116173017B (en) * | 2022-12-01 | 2025-02-07 | 浙江科瑞特生物科技有限公司 | A safe and efficient non-pronil general-purpose external anthelmintic for dogs and cats and its preparation method |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ232874A (en) * | 1989-03-13 | 1992-09-25 | Scient Chemicals Pty Ltd | Ectoparasiticide in polar solvent together miscible in aqueous component |
DE4417742A1 (en) * | 1994-05-20 | 1995-11-23 | Bayer Ag | Non-systemic control of parasites |
FR2739255B1 (en) * | 1995-09-29 | 1998-09-04 | Rhone Merieux | PEST CONTROL COMPOSITION FOR THE TREATMENT AND PROTECTION OF PETS |
IE80657B1 (en) * | 1996-03-29 | 1998-11-04 | Merial Sas | Insecticidal combination to control mammal fleas in particular fleas on cats and dogs |
FR2753377B1 (en) * | 1996-09-19 | 1999-09-24 | Rhone Merieux | NOVEL PARASITICIDE ASSOCIATION BASED ON 1-N-PHENYLPYRAZOLES AND ENDECTOCIDAL MACROCYCLIC LACTONES |
AU744790B2 (en) * | 1998-07-27 | 2002-03-07 | Sumitomo Chemical Company, Limited | Ectoparasite controlling agent for animals |
GB9912560D0 (en) * | 1999-05-28 | 1999-07-28 | Bob Martin Company The | Ectoparasite control composition |
AUPQ441699A0 (en) * | 1999-12-02 | 2000-01-06 | Eli Lilly And Company | Pour-on formulations |
NZ505779A (en) * | 2000-07-14 | 2003-06-30 | Akzo Nobel Nv | Pesticidal composition containing insect growth regulating (IGR) insecticide in an aromatic hydrocarbon and/or pyrrolidone and/or propylene glycol monoalkyl ether solvent system |
ATE467352T1 (en) * | 2003-05-19 | 2010-05-15 | Nippon Soda Co | INSECTICIDAL COMPOSITION |
US20050004475A1 (en) * | 2003-06-13 | 2005-01-06 | L'oreal | Method of comparing the appearance of a region of the human body at at least two different instants |
WO2005053746A1 (en) * | 2003-12-04 | 2005-06-16 | Jurox Pty Ltd | Improved parasiticide composition |
US7531186B2 (en) * | 2003-12-17 | 2009-05-12 | Merial Limited | Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz |
US7531187B2 (en) * | 2004-07-13 | 2009-05-12 | United Phosphorus, Ltd. | Synergistic insecticidal composition containing chloronicotynyle and pyrethroids compounds |
WO2006007630A1 (en) * | 2004-07-22 | 2006-01-26 | Jurox Pty Ltd | Aqueous insecticidal/parasiticide formulation |
US20060046988A1 (en) * | 2004-08-30 | 2006-03-02 | Albert Boeckh | Methoprene formulations for the control of tick infestations |
AU2005100403B4 (en) * | 2005-05-13 | 2005-09-01 | Jurox Pty Ltd | Parasiticide Composition |
SG10201401311QA (en) * | 2006-09-01 | 2014-07-30 | Du Pont | Local Topical Administration Formulations Containing Indoxacarb |
MX2009004620A (en) * | 2006-11-01 | 2009-05-15 | Veterinary Encapsulation Biosc | Delivery system for remote treatment of an animal. |
CN101288409A (en) * | 2007-04-21 | 2008-10-22 | 孔波 | Fipronil, chlopyrifos and production method thereof |
-
2008
- 2008-09-05 GB GB0816306A patent/GB2464449B/en active Active
-
2009
- 2009-09-02 WO PCT/GB2009/002107 patent/WO2010026370A1/en active Application Filing
- 2009-09-07 AR ARP090103425A patent/AR074974A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
GB0816306D0 (en) | 2008-10-15 |
GB2464449A (en) | 2010-04-21 |
GB2464449B (en) | 2011-10-12 |
WO2010026370A1 (en) | 2010-03-11 |
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Legal Events
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