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AR056465A1 - COMPOSITIONS CONTAINING DERIVATIVES OF TAXANO - Google Patents

COMPOSITIONS CONTAINING DERIVATIVES OF TAXANO

Info

Publication number
AR056465A1
AR056465A1 ARP060103597A AR056465A1 AR 056465 A1 AR056465 A1 AR 056465A1 AR P060103597 A ARP060103597 A AR P060103597A AR 056465 A1 AR056465 A1 AR 056465A1
Authority
AR
Argentina
Prior art keywords
derivatives
taxano
ether
ester
compositions containing
Prior art date
Application number
Other languages
Spanish (es)
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of AR056465A1 publication Critical patent/AR056465A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Composiciones basadas en derivados de taxano que comprenden una solucion de dichos derivados en un surfactante. Estas composiciones pueden ser utilizadas para preparar soluciones de perfusion. REIVINDICACION 1.- Una composicion farmacéutica adecuada para inyeccion o infusion intravenosa que comprende: - un derivado de taxano de formula (I) en donde R representa un átomo de hidrogeno o un radical acetilo y R1 representa un radical ter-butoxicarbonilamino o benzoilamino, - glicofurol como un solvente y, - un surfactante fisiologicamente aceptable seleccionado a partir del grupo consistente en cremophor, un éter o éster de polietilen glicol y un éter o éster de polioxietilen glicol.Compositions based on taxane derivatives comprising a solution of said derivatives in a surfactant. These compositions can be used to prepare perfusion solutions. CLAIM 1.- A pharmaceutical composition suitable for intravenous injection or infusion comprising: - a taxane derivative of formula (I) wherein R represents a hydrogen atom or an acetyl radical and R1 represents a tert-butoxycarbonylamino or benzoylamino radical, - glycofurol as a solvent and, - a physiologically acceptable surfactant selected from the group consisting of cremophor, an ether or ester of polyethylene glycol and an ether or ester of polyoxyethylene glycol.

ARP060103597 2005-08-19 2006-08-17 COMPOSITIONS CONTAINING DERIVATIVES OF TAXANO AR056465A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0517092A GB0517092D0 (en) 2005-08-19 2005-08-19 New compositions containing taxane derivatives

Publications (1)

Publication Number Publication Date
AR056465A1 true AR056465A1 (en) 2007-10-10

Family

ID=35098012

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060103597 AR056465A1 (en) 2005-08-19 2006-08-17 COMPOSITIONS CONTAINING DERIVATIVES OF TAXANO

Country Status (3)

Country Link
AR (1) AR056465A1 (en)
GB (1) GB0517092D0 (en)
WO (1) WO2007020085A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2516056C (en) 2003-01-06 2012-05-29 Angiochem Inc. Aprotinin and analogs as carriers across the blood-brain barrier
BRPI0520032A2 (en) 2005-02-18 2009-04-14 Angiochem Inc molecules to carry a compound through the blood brain barrier
EP2471555A3 (en) 2005-07-15 2012-10-17 Angiochem Inc. Use of aprotinin polypeptides as carriers in pharmaceutical conjugates
WO2007134354A1 (en) * 2006-05-23 2007-11-29 Ebewe Pharma Ges.M.B.H. Nfg. Kg Pharmaceutical formulation
US9365634B2 (en) 2007-05-29 2016-06-14 Angiochem Inc. Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
CN101327206B (en) * 2007-06-22 2011-07-20 成都市益斯生物科技有限公司 Docetaxel injection and preparation method thereof
AR063111A1 (en) * 2007-10-03 2008-12-30 Eriochem Sa A PHARMACEUTICAL FORMULATION OF TAXANO
KR101053780B1 (en) * 2008-02-29 2011-08-02 동아제약주식회사 Single liquid stable pharmaceutical composition containing docetaxel
EP2249839A4 (en) 2008-03-07 2013-10-16 Chemwerth Fulvestrant formulations
TR201905480T4 (en) * 2008-04-18 2019-05-21 Angiochem Inc Pharmaceutical compositions of paclitaxel, paclitaxel analogs or paclitaxel conjugates and their respective preparation and use methods.
ES2344674B1 (en) * 2008-08-07 2011-06-29 Gp Pharm, S.A. INJECTABLE PHARMACEUTICAL COMPOSITION OF TAXANOS.
WO2010043047A1 (en) 2008-10-15 2010-04-22 Angiochem Inc. Conjugates of glp-1 agonists and uses thereof
WO2010063122A1 (en) 2008-12-05 2010-06-10 Angiochem Inc. Conjugates of neurotensin or neurotensin analogs and uses thereof
CN102300987A (en) 2008-12-17 2011-12-28 安吉奥开米公司 Membrane Type-1 Matrix Metalloprotein Inhibitors And Uses Thereof
US9173891B2 (en) 2009-04-20 2015-11-03 Angiochem, Inc. Treatment of ovarian cancer using an anticancer agent conjugated to an angiopep-2 analog
IN2012DN00248A (en) 2009-07-02 2015-05-01 Angiochem Inc
US8912228B2 (en) 2009-10-19 2014-12-16 Scidose Llc Docetaxel formulations with lipoic acid
US7772274B1 (en) 2009-10-19 2010-08-10 Scidose, Llc Docetaxel formulations with lipoic acid
US20120172796A1 (en) * 2010-12-30 2012-07-05 Chappa Ralph A Composition for intravascular delivery of therapeutic composition
WO2013024495A1 (en) * 2011-08-18 2013-02-21 Dr. Reddys Laboratories Limited Pharmaceutical formulations of cabazitaxel
US11179468B2 (en) 2012-04-09 2021-11-23 Eagle Pharmaceuticals, Inc. Fulvestrant formulations
DK2875814T3 (en) 2012-07-19 2018-11-12 Fujifilm Corp LIQUID COMPOSITION CONTAINING TAXAN-BASED ACTIVE INGREDIENT, PROCEDURE FOR PREPARING IT AND LIQUID PHARMACEUTICAL COMPOSITION
US9012665B2 (en) 2012-07-31 2015-04-21 Yung Shin Pharm. Ind. Co., Ltd. Amorphous cabazitaxel
WO2014028704A1 (en) * 2012-08-15 2014-02-20 Yung Shin Pharm. Ind. Co., Ltd. Stable pharmaceutical formulation of cabazitaxel
JP6285725B2 (en) * 2014-01-16 2018-02-28 ナガセ医薬品株式会社 Ethanol-free docetaxel pharmaceutical composition
CN107921143B (en) 2015-06-15 2021-11-19 安吉奥开米公司 Method for treating leptomeningeal carcinomatosis
US10188626B2 (en) 2015-11-03 2019-01-29 Cipla Limited Stabilized cabazitaxel formulations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2678833B1 (en) * 1991-07-08 1995-04-07 Rhone Poulenc Rorer Sa NEW PHARMACEUTICAL COMPOSITIONS BASED ON DERIVATIVES OF THE TAXANE CLASS.
FR2698543B1 (en) * 1992-12-02 1994-12-30 Rhone Poulenc Rorer Sa New taxoid-based compositions.
CA2240595A1 (en) * 1995-12-21 1997-07-03 Bijan Almassian Taxane composition and method
AU2002239282A1 (en) * 2000-11-28 2002-06-11 Transform Pharmaceuticals, Inc. Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof
KR20050099311A (en) * 2004-04-09 2005-10-13 에이엔에이치 케어연구소(주) Composition for injection comprising anticancer drug

Also Published As

Publication number Publication date
WO2007020085A3 (en) 2007-11-08
GB0517092D0 (en) 2005-09-28
WO2007020085A2 (en) 2007-02-22

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