AR052917A1 - Proceso para preparar amidinas - Google Patents
Proceso para preparar amidinasInfo
- Publication number
- AR052917A1 AR052917A1 ARP060100623A ARP060100623A AR052917A1 AR 052917 A1 AR052917 A1 AR 052917A1 AR P060100623 A ARP060100623 A AR P060100623A AR P060100623 A ARP060100623 A AR P060100623A AR 052917 A1 AR052917 A1 AR 052917A1
- Authority
- AR
- Argentina
- Prior art keywords
- 4alkyl
- formula
- alkyl
- amidins
- prepare
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Indole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Un proceso para preparar un grupo amidina protegido de formula (1), donde R6 representa, por ejemplo, alquilo C1-10 (opcionalmente sustituido), arilo, alquilarilo C1-3 o alquiloxiarilo C1-3; el cual comprende: hacer reaccionar un compuesto que contiene nitrilo con una oxiamina de formula: R6ONH2, donde R6 es segun la definido anteriormente para la formula (1), en presencia de un agente activador de tio-ceto de formula: HS-Ry-C(O)-Z, donde Z es -alquiloC1-4, -OH, -O-alquiloC1-4, -SH, - SalquiloC1-4, -NH2, - NHalquiloC1-4 o -N(alquilo)2; Ry es alquilo C1-2 (opcionalmente sustituido); o Z y Ry están ligados de modo de formar un anillo de 5 o 6 miembros de formula (2); donde: X es -CH2-, -O-, -NH- o -NalquiloC1-4; p es 1 o 2; m es 1 o 2; y Rz se selecciona independientemente de H, alquilo C1-4, halo y amino.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0503672.8A GB0503672D0 (en) | 2005-02-23 | 2005-02-23 | New process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR052917A1 true AR052917A1 (es) | 2007-04-11 |
Family
ID=34401141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060100623A AR052917A1 (es) | 2005-02-23 | 2006-02-21 | Proceso para preparar amidinas |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US20080319206A1 (es) |
| EP (1) | EP1856035B1 (es) |
| JP (1) | JP2008531535A (es) |
| KR (1) | KR20070107150A (es) |
| CN (1) | CN101128419A (es) |
| AR (1) | AR052917A1 (es) |
| AT (1) | ATE417034T1 (es) |
| AU (1) | AU2006217728B2 (es) |
| BR (1) | BRPI0608219A2 (es) |
| CA (1) | CA2598496A1 (es) |
| CY (1) | CY1108826T1 (es) |
| DE (1) | DE602006004185D1 (es) |
| DK (1) | DK1856035T3 (es) |
| ES (1) | ES2317505T3 (es) |
| GB (1) | GB0503672D0 (es) |
| HK (1) | HK1112902A1 (es) |
| HR (1) | HRP20090070T3 (es) |
| IL (1) | IL184874A0 (es) |
| MX (1) | MX2007010277A (es) |
| MY (1) | MY139915A (es) |
| NO (1) | NO20073903L (es) |
| PL (1) | PL1856035T3 (es) |
| PT (1) | PT1856035E (es) |
| SI (1) | SI1856035T1 (es) |
| TW (1) | TW200640841A (es) |
| WO (1) | WO2006090153A1 (es) |
| ZA (1) | ZA200706260B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR035216A1 (es) | 2000-12-01 | 2004-05-05 | Astrazeneca Ab | Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios |
| AR034517A1 (es) | 2001-06-21 | 2004-02-25 | Astrazeneca Ab | Formulacion farmaceutica |
| SE0201661D0 (sv) * | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | New salts |
| US7781424B2 (en) * | 2003-05-27 | 2010-08-24 | Astrazeneca Ab | Modified release pharmaceutical formulation |
| SE0303220D0 (sv) | 2003-11-28 | 2003-11-28 | Astrazeneca Ab | New process |
| TW200827336A (en) | 2006-12-06 | 2008-07-01 | Astrazeneca Ab | New crystalline forms |
| TW200900033A (en) * | 2007-06-21 | 2009-01-01 | Wen-Qing Li | Automatic brewing machine |
| US20090061000A1 (en) * | 2007-08-31 | 2009-03-05 | Astrazeneca Ab | Pharmaceutical formulation use 030 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4661522A (en) * | 1984-05-24 | 1987-04-28 | Akzo N.V. | Cycloalkane-indene-carboximidamide derivatives |
| US5602172A (en) * | 1994-05-06 | 1997-02-11 | The University Of North Carolina At Chapel Hill | Methods of inhibiting Pneumocystis carinii pneumonia, Giardia lamblia, and Cryptosporidium and compounds useful therefor |
| US5723495A (en) * | 1995-11-16 | 1998-03-03 | The University Of North Carolina At Chapel Hill | Benzamidoxime prodrugs as antipneumocystic agents |
| US5672620A (en) * | 1996-02-01 | 1997-09-30 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| DE19635674A1 (de) * | 1996-09-03 | 1998-03-05 | Basf Ag | Verfahren zur Herstellung von Amidinen |
| MXPA03000643A (es) * | 2000-08-16 | 2003-06-06 | Astrazeneca Ab | Nuevos derivados de amidino y su uso como inhibidores de trombina. |
| AR035216A1 (es) * | 2000-12-01 | 2004-05-05 | Astrazeneca Ab | Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios |
| UA78195C2 (uk) * | 2001-08-30 | 2007-03-15 | Astrazeneca Ab | Похідні мигдалевої кислоти та їх застосування як інгібіторів тромбіну, фармацевтична композиція на їх основі |
| CA2504742A1 (en) * | 2002-11-27 | 2004-06-17 | University Of North Carolina At Chapel Hill | Process for synthesis bis-aryl diamidoxime compounds |
-
2005
- 2005-02-23 GB GBGB0503672.8A patent/GB0503672D0/en not_active Ceased
-
2006
- 2006-02-21 AR ARP060100623A patent/AR052917A1/es not_active Application Discontinuation
- 2006-02-21 MY MYPI20060737A patent/MY139915A/en unknown
- 2006-02-22 PT PT06709867T patent/PT1856035E/pt unknown
- 2006-02-22 DE DE602006004185T patent/DE602006004185D1/de active Active
- 2006-02-22 KR KR1020077021851A patent/KR20070107150A/ko not_active Application Discontinuation
- 2006-02-22 WO PCT/GB2006/000635 patent/WO2006090153A1/en active Application Filing
- 2006-02-22 PL PL06709867T patent/PL1856035T3/pl unknown
- 2006-02-22 AT AT06709867T patent/ATE417034T1/de not_active IP Right Cessation
- 2006-02-22 US US11/816,998 patent/US20080319206A1/en not_active Abandoned
- 2006-02-22 SI SI200630196T patent/SI1856035T1/sl unknown
- 2006-02-22 JP JP2007556659A patent/JP2008531535A/ja active Pending
- 2006-02-22 CA CA002598496A patent/CA2598496A1/en not_active Abandoned
- 2006-02-22 EP EP06709867A patent/EP1856035B1/en active Active
- 2006-02-22 DK DK06709867T patent/DK1856035T3/da active
- 2006-02-22 BR BRPI0608219-0A patent/BRPI0608219A2/pt not_active IP Right Cessation
- 2006-02-22 AU AU2006217728A patent/AU2006217728B2/en not_active Ceased
- 2006-02-22 MX MX2007010277A patent/MX2007010277A/es active IP Right Grant
- 2006-02-22 CN CNA2006800057501A patent/CN101128419A/zh active Pending
- 2006-02-22 ES ES06709867T patent/ES2317505T3/es active Active
- 2006-02-23 TW TW095106021A patent/TW200640841A/zh unknown
-
2007
- 2007-07-25 NO NO20073903A patent/NO20073903L/no not_active Application Discontinuation
- 2007-07-26 IL IL184874A patent/IL184874A0/en unknown
- 2007-07-27 ZA ZA200706260A patent/ZA200706260B/xx unknown
-
2008
- 2008-03-19 HK HK08103222.6A patent/HK1112902A1/xx not_active IP Right Cessation
-
2009
- 2009-02-05 HR HR20090070T patent/HRP20090070T3/xx unknown
- 2009-02-19 CY CY20091100197T patent/CY1108826T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101128419A (zh) | 2008-02-20 |
| IL184874A0 (en) | 2007-12-03 |
| DE602006004185D1 (de) | 2009-01-22 |
| ZA200706260B (en) | 2008-06-25 |
| KR20070107150A (ko) | 2007-11-06 |
| TW200640841A (en) | 2006-12-01 |
| CA2598496A1 (en) | 2006-08-31 |
| GB0503672D0 (en) | 2005-03-30 |
| HK1112902A1 (en) | 2008-09-19 |
| MX2007010277A (es) | 2007-09-11 |
| AU2006217728B2 (en) | 2010-02-18 |
| PL1856035T3 (pl) | 2009-05-29 |
| MY139915A (en) | 2009-11-30 |
| HRP20090070T3 (en) | 2009-03-31 |
| JP2008531535A (ja) | 2008-08-14 |
| US20080319206A1 (en) | 2008-12-25 |
| NO20073903L (no) | 2007-09-17 |
| WO2006090153A1 (en) | 2006-08-31 |
| BRPI0608219A2 (pt) | 2010-11-09 |
| EP1856035A1 (en) | 2007-11-21 |
| CY1108826T1 (el) | 2014-04-09 |
| ATE417034T1 (de) | 2008-12-15 |
| EP1856035B1 (en) | 2008-12-10 |
| PT1856035E (pt) | 2009-02-16 |
| DK1856035T3 (da) | 2009-03-09 |
| SI1856035T1 (sl) | 2009-04-30 |
| AU2006217728A1 (en) | 2006-08-31 |
| ES2317505T3 (es) | 2009-04-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR052917A1 (es) | Proceso para preparar amidinas | |
| AR051839A1 (es) | Metodo para preparar n-fenilpirazol -1- carboxamidas | |
| ATE506354T1 (de) | Substituierte arylcyclopropylacetamide als glucokinaseaktivatoren | |
| TW200600508A (en) | Cyclic amide derivative, and its production and use | |
| IL174471A (en) | A method for making quinolinone compounds and preparations containing such compounds | |
| UY35578A (es) | Síntesis de compuestos de ester y ácido bórico | |
| ATE372767T1 (de) | Dpp-iv-hemmer | |
| AR054533A1 (es) | Proceso y reactivo magnetico para la separacion de impurezas de los minerales | |
| UY29007A1 (es) | Derivados de 2-carbamida-4-feniltiazol, su preparacinn, y su aplicacinn en terapcutica | |
| EA200600621A1 (ru) | Производные тетрагидронафталина, способ их получения и их применение в качестве противовоспалительных средств | |
| HK1111168A1 (en) | A PROCESS FOR THE PREPARATION OF 17-HYDROXY-6 ß,7ß,15 ß,16 ß - BISMETHYLENE-17a-PREGN-4-ENE-3-ONE-21-CARBOXYLIC ACID Y-LACTONE AND KEY-INTERMEDIATES FOR THIS PROCESS | |
| HRP20050359B1 (hr) | Novi postupak za industrijsku sintezu stroncij renalata i njegovih hidrata | |
| EA200300927A1 (ru) | Новый способ промышленного синтеза тетрасложных эфиров 5-[бис(карбоксиметил)амино]-3-карбоксиметил-4-циано-2-тиофенкарбоновой кислоты и применение для синтеза бивалентных солей ранелиновой кислоты и их гидратов | |
| ATE368645T1 (de) | Aminosäurederivate als hiv-protease-inhibitoren | |
| SE0103710D0 (sv) | Compounds | |
| CY1107028T1 (el) | Παραγωγα ινδανυλ-πιπεραζινων μεθοδος παρασκευης αυτων και οι φαρμακευτικες συνθεσεις που τα περιεχουν | |
| BR0215709A (pt) | Processo para a preparação de cefdinir | |
| ATE441630T1 (de) | Substituierte cyclopenten-verbindungen | |
| PE20050483A1 (es) | Derivados de tetrazol de formula (i), sus composiciones farmaceuticas y procesos para producir composiciones farmaceuticas | |
| TW200628583A (en) | Compound and organic light emitting diode and display comprising the compound | |
| AR048876A1 (es) | Un proceso para preparar montelukast y compuestos intermedios para el mismo | |
| HRP20080440A2 (hr) | Postupak za proizvodnju spoja 5-alkoksi-4-hidroksimetilpirazola | |
| AR044175A1 (es) | Compuestos de cefemo | |
| AR043037A1 (es) | Benzo [1,2,5] tiadiazoles y su uso farmaceutico | |
| TW200702926A (en) | Compound dissolution inhibiting agent, positive resist composition, and resist pattern formation method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |