AR052155A1 - ORGANIC COMPOUNDS - Google Patents
ORGANIC COMPOUNDSInfo
- Publication number
- AR052155A1 AR052155A1 ARP050105195A ARP050105195A AR052155A1 AR 052155 A1 AR052155 A1 AR 052155A1 AR P050105195 A ARP050105195 A AR P050105195A AR P050105195 A ARP050105195 A AR P050105195A AR 052155 A1 AR052155 A1 AR 052155A1
- Authority
- AR
- Argentina
- Prior art keywords
- pharmaceutically acceptable
- water
- insoluble
- animal
- human
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Composicion que comprende un polímero termoplástico, un agente modificador de la velocidad y un agente biologicamente activo, util como implante de administracion de fármacos de liberacion lenta en el cuerpo de un ser humano o animal que se puede administrar en forma líquida en el cuerpo. Reivindicacion 1: Una composicion para formar un implante in situ dentro del cuerpo mediante la exposicion a los fluidos corporales, adecuada para una liberacion controlada del material bioactivo, que comprende un polímero termoplástico, biodegradable, farmacéuticamente aceptable, que es insoluble en un medio acuoso o en los fluidos corporales de un ser humano o animal, un solvente orgánico biodegradable, insoluble en agua o apenas soluble en agua, farmacéuticamente aceptable, un adyuvante biocompatible soluble en agua y farmacéuticamente aceptable y un agente biologicamente activo, caracterizado porque la cantidad en peso de dicho solvente es superior a la de dicho polímero termoplástico y porque el adyuvante se selecciona del grupo que comprende etanol, glicerol y glicerol formal.Composition comprising a thermoplastic polymer, a speed modifying agent and a biologically active agent, useful as a slow-release drug delivery implant in the body of a human or animal being that can be administered in liquid form in the body. Claim 1: A composition for forming an implant in situ within the body by exposure to body fluids, suitable for a controlled release of the bioactive material, comprising a thermoplastic, biodegradable, pharmaceutically acceptable polymer, which is insoluble in an aqueous medium or in the body fluids of a human or animal being, a biodegradable organic solvent, insoluble in water or barely soluble in water, pharmaceutically acceptable, a biocompatible water soluble and pharmaceutically acceptable adjuvant and a biologically active agent, characterized in that the amount by weight of said solvent is superior to that of said thermoplastic polymer and because the adjuvant is selected from the group comprising ethanol, glycerol and formal glycerol.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04029498 | 2004-12-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR052155A1 true AR052155A1 (en) | 2007-03-07 |
Family
ID=34927750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP050105195A AR052155A1 (en) | 2004-12-14 | 2005-12-12 | ORGANIC COMPOUNDS |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JP5372378B2 (en) |
| KR (1) | KR101304160B1 (en) |
| CN (1) | CN101056617B (en) |
| AR (1) | AR052155A1 (en) |
| AT (1) | ATE389386T1 (en) |
| AU (1) | AU2005315823B2 (en) |
| BR (1) | BRPI0519022A2 (en) |
| CA (1) | CA2585779C (en) |
| DE (1) | DE602005005522T2 (en) |
| ES (1) | ES2301084T3 (en) |
| MX (1) | MX2007007099A (en) |
| NZ (1) | NZ554904A (en) |
| RU (1) | RU2394558C2 (en) |
| TW (1) | TWI369218B (en) |
| WO (1) | WO2006063794A1 (en) |
| ZA (1) | ZA200703506B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
| ES2562878T3 (en) | 2007-05-25 | 2016-03-08 | Indivior Uk Limited | Sustained release formulations of risperidone compounds |
| CN101159064B (en) | 2007-11-29 | 2010-09-01 | 腾讯科技（深圳）有限公司 | Image generation system and method for generating image |
| US10064819B2 (en) | 2008-05-12 | 2018-09-04 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| US10588855B2 (en) | 2008-05-12 | 2020-03-17 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| US9877973B2 (en) | 2008-05-12 | 2018-01-30 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| JP6543431B2 (en) * | 2013-10-10 | 2019-07-10 | ユニバーシティー オブ ユタ リサーチ ファウンデーションＵｎｉｖｅｒｓｉｔｙ ｏｆ Ｕｔａｈ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ | Intraocular drug delivery device and associated method |
| PL3609470T3 (en) | 2017-04-13 | 2024-04-15 | Ceva Santé Animale | Implant for treating parasites infestations |
| CN112336682B (en) * | 2020-09-28 | 2022-07-08 | 浙江大学 | Injectable composite carrier and composition with slow and controlled release drug effect and preparation method |
| WO2024003291A1 (en) | 2022-06-30 | 2024-01-04 | Virbac | Deslorelin use in chemical castration of a non-human mammal related to pk/pd interaction |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4938763B1 (en) * | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
| US5324519A (en) * | 1989-07-24 | 1994-06-28 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| CN1146402C (en) * | 1996-12-20 | 2004-04-21 | 阿尔萨公司 | Injectable depot gel composition and method of preparing the composition |
| PL192270B1 (en) * | 1998-03-19 | 2006-09-29 | Merck & Co Inc | Liquid polymeric compositions for controlled release of bioactive substances |
| US7128927B1 (en) * | 1998-04-14 | 2006-10-31 | Qlt Usa, Inc. | Emulsions for in-situ delivery systems |
| JP4317606B2 (en) * | 1998-09-18 | 2009-08-19 | サンスター株式会社 | Solid particle forming composition |
| CN1713890A (en) * | 2002-11-06 | 2005-12-28 | 阿尔萨公司 | Controlled release depot formulations |
| WO2004081196A2 (en) * | 2003-03-11 | 2004-09-23 | Qlt Usa Inc. | Formulations for cell- schedule dependent anticancer agents |
-
2005
- 2005-12-12 AR ARP050105195A patent/AR052155A1/en unknown
- 2005-12-12 TW TW094143807A patent/TWI369218B/en not_active IP Right Cessation
- 2005-12-13 MX MX2007007099A patent/MX2007007099A/en active IP Right Grant
- 2005-12-13 BR BRPI0519022-3A patent/BRPI0519022A2/en not_active IP Right Cessation
- 2005-12-13 AU AU2005315823A patent/AU2005315823B2/en not_active Ceased
- 2005-12-13 JP JP2007545931A patent/JP5372378B2/en not_active Expired - Fee Related
- 2005-12-13 CN CN2005800386792A patent/CN101056617B/en not_active Expired - Fee Related
- 2005-12-13 CA CA2585779A patent/CA2585779C/en not_active Expired - Fee Related
- 2005-12-13 ES ES05815330T patent/ES2301084T3/en active Active
- 2005-12-13 DE DE602005005522T patent/DE602005005522T2/en active Active
- 2005-12-13 RU RU2007126759/15A patent/RU2394558C2/en not_active IP Right Cessation
- 2005-12-13 NZ NZ554904A patent/NZ554904A/en not_active IP Right Cessation
- 2005-12-13 AT AT05815330T patent/ATE389386T1/en not_active IP Right Cessation
- 2005-12-13 KR KR1020077013264A patent/KR101304160B1/en not_active IP Right Cessation
- 2005-12-13 WO PCT/EP2005/013377 patent/WO2006063794A1/en active Application Filing
-
2007
- 2007-05-02 ZA ZA200703506A patent/ZA200703506B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2394558C2 (en) | 2010-07-20 |
| WO2006063794A1 (en) | 2006-06-22 |
| KR101304160B1 (en) | 2013-09-04 |
| DE602005005522T2 (en) | 2009-04-16 |
| JP2008523131A (en) | 2008-07-03 |
| ATE389386T1 (en) | 2008-04-15 |
| AU2005315823A1 (en) | 2006-06-22 |
| CN101056617A (en) | 2007-10-17 |
| DE602005005522D1 (en) | 2008-04-30 |
| RU2007126759A (en) | 2009-01-27 |
| CN101056617B (en) | 2012-07-11 |
| AU2005315823B2 (en) | 2009-06-04 |
| MX2007007099A (en) | 2007-06-22 |
| KR20070092964A (en) | 2007-09-14 |
| ZA200703506B (en) | 2008-09-25 |
| CA2585779A1 (en) | 2006-06-22 |
| TW200635616A (en) | 2006-10-16 |
| BRPI0519022A2 (en) | 2008-12-23 |
| ES2301084T3 (en) | 2008-06-16 |
| JP5372378B2 (en) | 2013-12-18 |
| CA2585779C (en) | 2014-01-28 |
| NZ554904A (en) | 2009-11-27 |
| TWI369218B (en) | 2012-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |