AR042956A1 - Inhibidores de girasa y usos de los mismos - Google Patents

Inhibidores de girasa y usos de los mismos

Info

Publication number: AR042956A1
Authority: AR; Argentina
Prior art keywords: independently selected; ring; so2r; membered; saturated
Prior art date: 2003-01-31

Application number

ARP040100257A

Other languages

English (en)

Spanish (es)

Inventor

Paul S Charifson

D Deininger

Anne-Laure Grillot

Yusheng Llao

Steven Ronkin

Dean Stamos

Emanuele Perola

Arnaud Letiran

Joseph Drumm

Tiensheng Wang

Original Assignee

Vertex Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-01-31

Filing date

2004-01-28

Publication date

2005-07-13

2004-01-28 Application filed by Vertex Pharma filed Critical Vertex Pharma

2005-07-13 Publication of AR042956A1 publication Critical patent/AR042956A1/es

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

ARP040100257A 2003-01-31 2004-01-28 Inhibidores de girasa y usos de los mismos AR042956A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US44391703P	2003-01-31	2003-01-31

Publications (1)

Publication Number	Publication Date
AR042956A1 true AR042956A1 (es)	2005-07-13

Family

ID=34115255

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ARP040100257A AR042956A1 (es)	2003-01-31	2004-01-28	Inhibidores de girasa y usos de los mismos

Country Status (24)

Country	Link
US (3)	US7495014B2 (da)
EP (1)	EP1592686B1 (da)
JP (2)	JP4691033B2 (da)
KR (1)	KR20060056270A (da)
CN (1)	CN100393714C (da)
AR (1)	AR042956A1 (da)
AT (1)	ATE435859T1 (da)
AU (1)	AU2004261545B2 (da)
CA (1)	CA2513463C (da)
CY (1)	CY1109385T1 (da)
DE (1)	DE602004021904D1 (da)
DK (1)	DK1592686T3 (da)
ES (1)	ES2327642T3 (da)
IL (1)	IL169720A (da)
MX (1)	MXPA05008126A (da)
MY (1)	MY139124A (da)
NO (1)	NO20053845L (da)
NZ (1)	NZ541885A (da)
PT (1)	PT1592686E (da)
RU (1)	RU2350612C2 (da)
SI (1)	SI1592686T1 (da)
TW (1)	TWI334416B (da)
WO (1)	WO2005012292A1 (da)
ZA (1)	ZA200505773B (da)

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TWI595002B (zh) *	2012-07-18	2017-08-11	思沛羅三南公司	（Ｒ）－２－（５－（２－（３－乙基脲基）－６－氟－７－（四氫呋喃－２－基）－１Ｈ－苯并［ｄ］咪唑－５－基）嘧啶－２－基）丙烷－２－基磷酸二氫鹽之固體形式及其鹽
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AR092742A1 (es)	2012-10-02	2015-04-29	Intermune Inc	Piridinonas antifibroticas
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CN106459042B (zh)	2014-04-02	2019-06-28	英特穆恩公司	抗纤维化吡啶酮类
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HK1245248B (en)	2014-12-11	2020-05-15	恒翼生物医药(上海)股份有限公司	Substituted heterocycles as bromodomain inhibitors
US10231953B2 (en)	2014-12-17	2019-03-19	Zenith Epigenetics Ltd.	Inhibitors of bromodomains
CN105884752B (zh) *	2015-02-13	2018-08-31	山东轩竹医药科技有限公司	并环类回旋酶和拓扑异构酶iv抑制剂
WO2016187620A2 (en)	2015-05-21	2016-11-24	The Regents Of The University Of California	Anti-cancer compounds
CN106167486B (zh) *	2015-05-22	2019-06-14	北京四环制药有限公司	单环类回旋酶和拓扑异构酶iv抑制剂
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EA201991997A1 (ru)	2017-03-01	2020-01-22	Янссен Сайенсиз Айрлэнд Анлимитед Компани	Комбинированная терапия
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CN101321744A (zh)	2005-11-07	2008-12-10	沃泰克斯药物股份有限公司	作为回旋酶抑制剂的苯并咪唑衍生物

2004
- 2004-01-28 AR ARP040100257A patent/AR042956A1/es unknown
- 2004-01-29 MX MXPA05008126A patent/MXPA05008126A/es active IP Right Grant
- 2004-01-29 NZ NZ541885A patent/NZ541885A/en unknown
- 2004-01-29 AU AU2004261545A patent/AU2004261545B2/en not_active Ceased
- 2004-01-29 AT AT04775744T patent/ATE435859T1/de active
- 2004-01-29 WO PCT/US2004/002541 patent/WO2005012292A1/en not_active Ceased
- 2004-01-29 US US10/767,638 patent/US7495014B2/en not_active Expired - Fee Related
- 2004-01-29 EP EP04775744A patent/EP1592686B1/en not_active Expired - Lifetime
- 2004-01-29 ES ES04775744T patent/ES2327642T3/es not_active Expired - Lifetime
- 2004-01-29 CA CA2513463A patent/CA2513463C/en not_active Expired - Fee Related
- 2004-01-29 KR KR1020057014085A patent/KR20060056270A/ko not_active Abandoned
- 2004-01-29 DK DK04775744T patent/DK1592686T3/da active
- 2004-01-29 JP JP2006532271A patent/JP4691033B2/ja not_active Expired - Fee Related
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- 2004-01-29 CN CNB2004800030868A patent/CN100393714C/zh not_active Expired - Fee Related
- 2004-01-29 SI SI200431228T patent/SI1592686T1/sl unknown
- 2004-01-29 RU RU2005127328/04A patent/RU2350612C2/ru not_active IP Right Cessation
- 2004-01-29 DE DE602004021904T patent/DE602004021904D1/de not_active Expired - Lifetime
- 2004-01-29 PT PT04775744T patent/PT1592686E/pt unknown
- 2004-01-30 TW TW093102200A patent/TWI334416B/zh not_active IP Right Cessation
2005
- 2005-07-18 IL IL169720A patent/IL169720A/en not_active IP Right Cessation
- 2005-08-16 NO NO20053845A patent/NO20053845L/no not_active Application Discontinuation
2008
- 2008-10-07 US US12/246,778 patent/US8188095B2/en not_active Expired - Fee Related
2009
- 2009-09-17 CY CY20091100962T patent/CY1109385T1/el unknown
2010
- 2010-12-06 JP JP2010272049A patent/JP2011046745A/ja not_active Withdrawn
2012
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Also Published As

Publication number	Publication date
ES2327642T3 (es)	2009-11-02
JP2006528677A (ja)	2006-12-21
HK1087699A1 (zh)	2006-10-20
US20130023525A1 (en)	2013-01-24
MY139124A (en)	2009-08-28
CA2513463A1 (en)	2005-02-10
PT1592686E (pt)	2009-08-25
NO20053845L (no)	2005-08-16
SI1592686T1 (sl)	2009-12-31
IL169720A (en)	2011-08-31
EP1592686A1 (en)	2005-11-09
CN1745077A (zh)	2006-03-08
TW200503708A (en)	2005-02-01
RU2350612C2 (ru)	2009-03-27
RU2005127328A (ru)	2006-02-10
AU2004261545B2 (en)	2010-06-24
AU2004261545A1 (en)	2005-02-10
WO2005012292A1 (en)	2005-02-10
US8188095B2 (en)	2012-05-29
DE602004021904D1 (de)	2009-08-20
US20090176771A1 (en)	2009-07-09
CA2513463C (en)	2012-07-10
EP1592686B1 (en)	2009-07-08
KR20060056270A (ko)	2006-05-24
JP2011046745A (ja)	2011-03-10
MXPA05008126A (es)	2006-03-30
US7495014B2 (en)	2009-02-24
NZ541885A (en)	2009-01-31
JP4691033B2 (ja)	2011-06-01
DK1592686T3 (da)	2009-10-19
ATE435859T1 (de)	2009-07-15
CN100393714C (zh)	2008-06-11
ZA200505773B (en)	2006-09-27
US20040235886A1 (en)	2004-11-25
CY1109385T1 (el)	2014-07-02
TWI334416B (en)	2010-12-11

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