[go: up one dir, main page]

AR040859A1 - Composiciones farmaceuticas que comprenden una ascomicina - Google Patents

Composiciones farmaceuticas que comprenden una ascomicina

Info

Publication number
AR040859A1
AR040859A1 AR20030102913A ARP030102913A AR040859A1 AR 040859 A1 AR040859 A1 AR 040859A1 AR 20030102913 A AR20030102913 A AR 20030102913A AR P030102913 A ARP030102913 A AR P030102913A AR 040859 A1 AR040859 A1 AR 040859A1
Authority
AR
Argentina
Prior art keywords
ascomycin
pharmaceutical compositions
weight
alkyl ester
component
Prior art date
Application number
AR20030102913A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AR040859A1 publication Critical patent/AR040859A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Composiciones farmacéuticas líquidas o semisólidas de una sola fase sustancialmente exentas de etanol y agua, y que comprenden una ascomicina, tal como pimecrolimus, en un vehículo portador que comprende una mezcla de solventes de tres componentes que suman cuando menos el 40 % en peso/peso del peso total de la composición, y que consiste en: i) un alcanol C3-8 y/o alcanodiol C1-8; ii) un alcohol graso ; y iii) un solvente adicional seleccionado a partir de: a) un alquiléster de ácido alcancarboxílico y/o alquiléster de ácido alcandicarboxílico, y/o b) un co-componente hidrofílico, y/o c) un triglicérido; y opcionalmente, excipientes convencionales adicionales.
AR20030102913A 2002-08-14 2003-08-12 Composiciones farmaceuticas que comprenden una ascomicina AR040859A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0218996.7A GB0218996D0 (en) 2002-08-14 2002-08-14 Organic compounds

Publications (1)

Publication Number Publication Date
AR040859A1 true AR040859A1 (es) 2005-04-20

Family

ID=9942370

Family Applications (1)

Application Number Title Priority Date Filing Date
AR20030102913A AR040859A1 (es) 2002-08-14 2003-08-12 Composiciones farmaceuticas que comprenden una ascomicina

Country Status (23)

Country Link
US (1) US20050220850A1 (es)
EP (1) EP1534339B1 (es)
JP (1) JP2005537302A (es)
KR (1) KR100624583B1 (es)
CN (1) CN1674940A (es)
AR (1) AR040859A1 (es)
AT (1) ATE445416T1 (es)
AU (1) AU2003258607B2 (es)
BR (1) BR0313462A (es)
CA (1) CA2495345A1 (es)
DE (1) DE60329687D1 (es)
EC (1) ECSP055597A (es)
GB (1) GB0218996D0 (es)
IL (1) IL166601A0 (es)
MX (1) MXPA05001767A (es)
NO (1) NO20051232L (es)
NZ (1) NZ538138A (es)
PE (1) PE20040330A1 (es)
PL (1) PL373230A1 (es)
RU (1) RU2343919C2 (es)
TW (1) TW200410713A (es)
WO (1) WO2004016289A1 (es)
ZA (1) ZA200500815B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0307866D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Pharmaceutical composition
ES2389443T3 (es) * 2004-04-08 2012-10-26 Meda Pharma S.À.R.L. Composición de espuma de pimecrolimus que contiene hexilenglicol, opcionalmente alcohol de oleílo, dimetilisosorbida y/o triglicéridos de cadena media
US20080207670A1 (en) * 2004-09-16 2008-08-28 Bayer Healthcare Ag Dermally Applicable Formulations For Treating Skin Diseases in Animals
GB0425255D0 (en) * 2004-11-16 2004-12-15 Novartis Ag Pharmaceutical composition
DE102005037844A1 (de) * 2005-08-04 2007-04-05 Intendis Gmbh Wasserfreies Mehr-Phasen-Gel-System
GB0518769D0 (en) * 2005-09-14 2005-10-19 Medpharm Ltd Topical formulations
US9205080B2 (en) 2006-11-16 2015-12-08 Transderm, Inc. Methods of treating keratin hyperproliferation disorders using mTOR inhibitors
CA2769625C (en) 2009-07-29 2017-04-11 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
AU2010302350B2 (en) 2009-10-02 2015-06-18 Journey Medical Corporation Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
EP2948134B1 (en) 2013-01-24 2020-03-04 Palvella Therapeutics, Inc. Compositions for transdermal delivery of mtor inhibitors
CA2978573A1 (en) 2016-09-08 2018-03-08 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne
FR3061009B1 (fr) * 2016-12-22 2020-09-25 Oreal Composition cosmetique comprenant une ou plusieurs huile(s) polaire(s), un monoalcool aliphatique en c2-c6 et un polyol, au moins un actif hydrophile, et comprenant moins de 7% en poids d’eau
FR3061008B1 (fr) * 2016-12-22 2020-05-01 L'oreal Composition cosmetique comprenant une ou plusieurs huile(s) polaire(s), un monoalcool aliphatique en c2-c6 et un polyol, et comprenant moins de 5% en poids d’eau
CN110520097B (zh) * 2017-01-06 2023-10-27 帕尔维拉治疗股份有限公司 Mtor抑制剂的无水组合物及其使用方法
US11000513B2 (en) 2018-07-02 2021-05-11 Palvella Therapeutics, Inc. Anhydrous compositions of mTOR inhibitors and methods of use
FR3104962B1 (fr) * 2019-12-20 2021-12-31 Oreal Composition cosmétique comprenant au moins une huile polaire, un monoalcool aliphatique, un mélange de polyols et au moins un actif hydrophile
CN116602914B (zh) * 2023-07-05 2024-02-13 江苏知原药业股份有限公司 一种皮炎用乳膏及其生产工艺及其生产设备

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537776A (en) * 1983-06-21 1985-08-27 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
DE69125230T2 (de) * 1990-09-04 1997-07-10 Fujisawa Pharmaceutical Co Tricyclische Verbindungen enthaltende Salben
CH686761A5 (de) * 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
JPH06345646A (ja) * 1993-06-08 1994-12-20 Fujisawa Pharmaceut Co Ltd ローション剤
CA2183083C (en) * 1994-03-07 2006-01-03 Charles D. Ebert Drug-containing adhesive composite transdermal delivery device
ES2173978T3 (es) * 1994-10-26 2002-11-01 Novartis Ag Utilizacion de un alcohol graso insaturado.
GB2327610B (en) * 1994-11-04 1999-06-02 Novartis Ag Macrolide compositions
HUP0104452A3 (en) * 1998-04-27 2004-05-28 Fujisawa Pharmaceutical Co Medicinal compositions, containing tricyclo compounds
GB9826656D0 (en) * 1998-12-03 1999-01-27 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
ATE445416T1 (de) 2009-10-15
BR0313462A (pt) 2005-07-05
US20050220850A1 (en) 2005-10-06
AU2003258607A1 (en) 2004-03-03
ZA200500815B (en) 2006-07-26
KR20050042475A (ko) 2005-05-09
EP1534339A1 (en) 2005-06-01
ECSP055597A (es) 2005-04-18
WO2004016289A1 (en) 2004-02-26
AU2003258607B2 (en) 2007-01-04
GB0218996D0 (en) 2002-09-25
EP1534339B1 (en) 2009-10-14
MXPA05001767A (es) 2005-04-25
NO20051232L (no) 2005-05-12
PE20040330A1 (es) 2004-07-15
KR100624583B1 (ko) 2006-09-15
TW200410713A (en) 2004-07-01
IL166601A0 (en) 2006-01-15
CA2495345A1 (en) 2004-02-26
JP2005537302A (ja) 2005-12-08
RU2005107317A (ru) 2005-10-10
CN1674940A (zh) 2005-09-28
NZ538138A (en) 2008-05-30
RU2343919C2 (ru) 2009-01-20
DE60329687D1 (de) 2009-11-26
PL373230A1 (en) 2005-08-22

Similar Documents

Publication Publication Date Title
AR040859A1 (es) Composiciones farmaceuticas que comprenden una ascomicina
CO5700671A2 (es) Formulaciones topicas que comprenden un derivado de 1-n-arilpirazol y una formamidina
ES2600729T3 (es) Conjugados de polímeros hiperramificados a través de enlazante escindible no enzimático
RU2011111206A (ru) Композиции для местного применения, содержащие комбинацию по меньшей мере двух агентов, усиливающих проникновение
PE20030865A1 (es) Composiciones farmaceuticas para inhibidores de proteasa viral de la hepatitis c
AR023939A1 (es) COMPUESTOS DERIVADOS DE PIPERIDINA uTILES COMO ANTAGONISTAS DE CCR5, COMPOSICIONES FARMACÉUTICAS QUE LOS CONTIENEN, EL USO DE LOS MISMOS SOLOS O EN COMBINACIoN CON OTRO AGENTE ANTIVIRAL PARA LA PREPARACIoN DE UN MEDICAMENTO Y UN KIT
CA2864118A1 (en) Formulations of bendamustine
IL142535A0 (en) Pharmaceutical compositions for the treatment of inflammation
EP1914231A3 (de) 2-Methyl-2-alkenyl-substituierte 1,3-Dioxane als Riechstoffe
AR030312A1 (es) Composicion novedosa para la administracion transdermica y/o transmucosica de compuestos activos, que asegura adecuados niveles terapeuticos
ES2173978T3 (es) Utilizacion de un alcohol graso insaturado.
PE37797A1 (es) Espesadores asociativos
CO5590905A2 (es) Composiciones farmaceuticas que comprenden compuestos activos de vitamina d
PE20120032A1 (es) Composicion farmaceutica oral de un derivado de n-[4-(8-bromo-7-metoxiquinolin-2-il)-1,3-tiazol-2-il]-2-metilpropanamida
UY29825A1 (es) Derivados sustituidos de 3h-imidazol-(4,5 b (beta))piridina-2-il benzoatos y benzamidas, composiciones farmacéuticas que los contienen y aplicaciones
HRP20110588T1 (hr) Novi cikloheksenonski spojevi iz antrodia camphorata i njihova primjena
BR0318651A (pt) processo melhorado para preparar ésteres alquil de ácido graxo usado como biodiesel
CO5700724A2 (es) Metodos y composiciones farmaceuticas para la obtencion confiable de niveles aceptables de testosterona en suero
ATE473976T1 (de) Dipeptidylpeptidase-iv-inhibierende verbindungen, verfahren zu deren herstellung und pharmazeutische zusammensetzungen, die diese als wirkstoffe enthalten
CO5221123A1 (es) Desodorante con pequenas particulas de oxido de zinc
BRPI0509854A (pt) composto, métodos para a preparação regio-especìfica de um 42-éster de rapamicina ou 42-éster de prolina-rapamicina e para a preparação de um 42-éster de prolina-rapamicina, composição, e, produto
AR093297A1 (es) Formulacion liquida que comprende un compuesto neutralizante de gm-csf
JP2012531470A5 (es)
AR005827A1 (es) Compuesto derivado de nucleosidos aciclicos, composicion farmaceutica que lo comprende, uso del mismo en la preparacion de un medicamento y su metodo de preparacion
AR001931A1 (es) Compuesto de 7-acilamino-3-iminometil (sustituido)cefalosporinas un proceso para su producción intermediarios en su producción una composición farmacéutica que contiene tales compuestos su utilizacióncomo compuestos farmacéuticos y un método para tratar enfermedades microbianas mediante administración de tales compuestos

Legal Events

Date Code Title Description
FA Abandonment or withdrawal