AR039037A1 - Un sistema de liberacion de una droga vaginal con un ph esencialmente neutro y un metodo para tratar una enfermedad vaginal que comprende dicho sistema - Google Patents
Un sistema de liberacion de una droga vaginal con un ph esencialmente neutro y un metodo para tratar una enfermedad vaginal que comprende dicho sistemaInfo
- Publication number
- AR039037A1 AR039037A1 ARP030100979A ARP030100979A AR039037A1 AR 039037 A1 AR039037 A1 AR 039037A1 AR P030100979 A ARP030100979 A AR P030100979A AR P030100979 A ARP030100979 A AR P030100979A AR 039037 A1 AR039037 A1 AR 039037A1
- Authority
- AR
- Argentina
- Prior art keywords
- vaginal
- phase
- essentially neutral
- drug
- release system
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 5
- 229940079593 drug Drugs 0.000 title abstract 5
- 230000007935 neutral effect Effects 0.000 title abstract 3
- 208000013464 vaginal disease Diseases 0.000 title 1
- 239000012071 phase Substances 0.000 abstract 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 1
- 239000011149 active material Substances 0.000 abstract 1
- 210000000601 blood cell Anatomy 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 239000008384 inner phase Substances 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Tropical Medicine & Parasitology (AREA)
- Urology & Nephrology (AREA)
- AIDS & HIV (AREA)
- Diabetes (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Sistema de liberación de una droga vaginal con un pH esencialmente neutro adecuado para la liberación modificada de un material terapéuticamente activo en la cavidad vaginal. El sistema de liberación de la droga vaginal comprende una emulsión con un pH esencialmente neutro que tiene glóbulos que tienen dos fases, una fase interna soluble en agua y una fase externa insoluble en agua o película, en donde la fase interior soluble en agua contiene una droga o drogas terapéuticamente activa(s). Un aspecto novedoso del sistema de liberación de droga vaginal es que la fase interna soluble en agua comprende una fase ácida regulada.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/101,014 US6899890B2 (en) | 2002-03-20 | 2002-03-20 | Bioadhesive drug delivery system |
Publications (1)
Publication Number | Publication Date |
---|---|
AR039037A1 true AR039037A1 (es) | 2005-02-02 |
Family
ID=22282669
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP030100979A AR039037A1 (es) | 2002-03-20 | 2003-03-20 | Un sistema de liberacion de una droga vaginal con un ph esencialmente neutro y un metodo para tratar una enfermedad vaginal que comprende dicho sistema |
Country Status (17)
Country | Link |
---|---|
US (1) | US6899890B2 (es) |
EP (1) | EP1494630A4 (es) |
JP (1) | JP4462818B2 (es) |
KR (2) | KR20030076159A (es) |
CN (3) | CN101045034A (es) |
AR (1) | AR039037A1 (es) |
AU (2) | AU2002300175B2 (es) |
BR (1) | BR0202767A (es) |
CA (1) | CA2392473C (es) |
FR (1) | FR2837389A1 (es) |
HU (1) | HUP0203102A3 (es) |
IT (1) | ITMI20021660A1 (es) |
MX (1) | MXPA02006943A (es) |
PT (1) | PT102854B (es) |
RU (1) | RU2320322C2 (es) |
WO (1) | WO2003079981A2 (es) |
ZA (1) | ZA200407535B (es) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7060732B2 (en) * | 2000-12-12 | 2006-06-13 | Imaginative Research Associates, Inc. | Antibiotic/benzoyl peroxide dispenser |
US20060189552A1 (en) * | 2000-12-12 | 2006-08-24 | Mohan Vishnupad | Dispenser for dispensing three or more actives |
US6899890B2 (en) * | 2002-03-20 | 2005-05-31 | Kv Pharmaceutical Company | Bioadhesive drug delivery system |
US20060083759A1 (en) * | 2002-07-17 | 2006-04-20 | Aleksander Resman | Stabilization of the profile of release of active substances from a formulation |
WO2004105662A1 (en) * | 2003-05-23 | 2004-12-09 | Program For Appropriate Technology In Health | Microbicidal compositions and methods of use |
ITTO20030404A1 (it) * | 2003-05-30 | 2004-11-30 | Rottapharm S R L | Composizione per il ripristino dell'ecosistema vaginale |
GB0315671D0 (en) * | 2003-07-04 | 2003-08-13 | Chelsea And Westminster Nhs Tr | Improvements in or relating to organic compounds |
US20060140990A1 (en) | 2003-09-19 | 2006-06-29 | Drugtech Corporation | Composition for topical treatment of mixed vaginal infections |
US20050095245A1 (en) * | 2003-09-19 | 2005-05-05 | Riley Thomas C. | Pharmaceutical delivery system |
DE602004028284D1 (de) | 2003-12-08 | 2010-09-02 | Cpex Pharmaceuticals Inc | Pharmazeutische zusammensetzungen und verfahren für die insulinbehandlung |
US8057433B2 (en) | 2004-07-08 | 2011-11-15 | Drugtech Corporation | Delivery system |
UA93354C2 (ru) * | 2004-07-09 | 2011-02-10 | Гилиад Сайенсиз, Инк. | Местный противовирусный препарат |
US20060093675A1 (en) * | 2004-10-29 | 2006-05-04 | Mathew Ebmeier | Intravaginal treatment of vaginal infections with metronidazole compositions |
US7619008B2 (en) * | 2004-11-12 | 2009-11-17 | Kimberly-Clark Worldwide, Inc. | Xylitol for treatment of vaginal infections |
US20060217443A1 (en) * | 2005-03-28 | 2006-09-28 | Kimberly-Clark Worldwide, Inc. | Method for preventing and/or treating vaginal and vulval infections |
BRPI0612968A2 (pt) | 2005-04-27 | 2010-12-14 | Shenzhen Phlora Biotechnology Ltd | uso do Ácido benzàico e/ou seu sal de sàdio em combinaÇço com sacarÍdeos, composiÇço vaginal e mÉtodo para modular a flora vaginal e a acidez vaginal |
WO2006121429A1 (en) * | 2005-05-06 | 2006-11-16 | Imaginative Research Associates, Inc. | Clindamycin compositions and delivery system therefor |
AU2006244260A1 (en) * | 2005-05-09 | 2006-11-16 | Drugtech Corporation | Modified-release pharmaceutical compositions |
US7786176B2 (en) * | 2005-07-29 | 2010-08-31 | Kimberly-Clark Worldwide, Inc. | Vaginal treatment composition containing xylitol |
WO2007021964A2 (en) | 2005-08-11 | 2007-02-22 | Massachusetts Institute Of Technology | Intravesical drug delivery device and method |
JP2009504667A (ja) * | 2005-08-12 | 2009-02-05 | ドラッグテック コーポレイション | エストロゲン組成物およびその使用による治療方法 |
US20070154516A1 (en) * | 2006-01-05 | 2007-07-05 | Drugtech Corporation | Drug delivery system |
CN101374501A (zh) * | 2006-01-05 | 2009-02-25 | 药物技术公司 | 组合物及其使用方法 |
JP2009526064A (ja) * | 2006-02-09 | 2009-07-16 | シェーリング コーポレイション | 薬学的調合物 |
EP1872775A1 (en) * | 2006-06-29 | 2008-01-02 | Polichem S.A. | Use of a hydrophilic matrix comprising a polyacrylic acid derivative, a cellulose ether and a disintegrant for the manufacture of a medicament for treating female genital disorders |
US20080003262A1 (en) * | 2006-06-30 | 2008-01-03 | Drugtech Corporation | Compositions and therapeutic methods of use |
US20080085877A1 (en) * | 2006-08-10 | 2008-04-10 | Drugtech Corporation | Therapeutic methods of using estrogen compositions |
US20080268022A1 (en) * | 2007-02-23 | 2008-10-30 | Mccabe R Tyler | Mehtods for treating and preventing ailments caused by human papillomavirus |
US20080287408A1 (en) * | 2007-05-14 | 2008-11-20 | Drugtech Corporation | Endometriosis treatment |
EP1994938A1 (en) * | 2007-05-21 | 2008-11-26 | Combinature Biopharm AG | New lipoglycodepsipeptide compositions |
PL2231254T3 (pl) | 2007-12-11 | 2014-10-31 | Massachusetts Inst Technology | Implantowane urządzenie do dostarczania leku |
US20090238867A1 (en) * | 2007-12-13 | 2009-09-24 | Scott Jenkins | Nanoparticulate Anidulafungin Compositions and Methods for Making the Same |
CA2733468C (en) | 2008-08-09 | 2017-12-05 | Massachusetts Institute Of Technology | Implantable drug delivery device and methods of treating male genitourinary and surrounding tissues |
EP2400988B1 (en) * | 2009-02-26 | 2016-04-13 | B.R.A.I.N. Biotechnology Research and Information Network AG | Compositions, use and method for the use of surface active proteins in topical drug delivery across keratin |
CN102481438B (zh) | 2009-06-26 | 2013-09-18 | 塔里斯生物医药公司 | 可植入药物递送装置及制造所述装置的方法 |
US20110008469A1 (en) * | 2009-07-09 | 2011-01-13 | Florida Gulf Coast University | Antimicrobial composition and methods and apparatus for use thereof |
US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
EP2538929A4 (en) | 2010-02-25 | 2014-07-09 | Univ Johns Hopkins | DELAYED RELEASE OF THERAPIES IN A PART OF THE EYE |
RU2479305C2 (ru) * | 2010-12-06 | 2013-04-20 | Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") | Фармацевтическая композиция для лечения инфекционных воспалительных заболеваний в гинекологии и способ ее получения |
EP2663300B1 (en) | 2011-01-10 | 2023-03-08 | TARIS Biomedical LLC | Lidocaine regimen for the use of sustained treatment of bladder pain and irritative voiding |
US9107816B2 (en) | 2011-02-04 | 2015-08-18 | Taris Biomedical Llc | Implantable device for controlled dissolution and diffusion of low solubility drug |
WO2012109363A2 (en) | 2011-02-08 | 2012-08-16 | The Johns Hopkins University | Mucus penetrating gene carriers |
US9226908B2 (en) | 2011-04-04 | 2016-01-05 | Environ Skin Care (Pty) Ltd | Treatment of viral infections |
AR086249A1 (es) | 2011-05-02 | 2013-11-27 | Aptalis Pharmatech Inc | Composiciones de tabletas de disolucion rapida de administracion vaginal |
EP2757904B1 (en) * | 2011-09-19 | 2017-01-11 | OmniActive Health Technologies Limited | An efficient process for the preparation of lycopene containing oleoresin and lycopene crystals for human consumption |
US9180094B2 (en) | 2011-10-12 | 2015-11-10 | The Texas A&M University System | High porosity materials, scaffolds, and method of making |
CN104936620B (zh) * | 2012-01-19 | 2019-08-09 | 约翰霍普金斯大学 | 增强粘膜渗透的纳米粒子调配物 |
WO2014018075A1 (en) | 2012-07-23 | 2014-01-30 | Crayola, Llc | Dissolvable films and methods of using the same |
RU2538703C2 (ru) * | 2013-03-12 | 2015-01-10 | Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") | Фармацевтическая композиция для лечения вагинального кандидоза и способ ее получения |
SG11201507294WA (en) | 2013-03-15 | 2015-10-29 | Taris Biomedical Llc | Drug delivery devices with drug-permeable component and methods |
WO2014192791A1 (ja) * | 2013-05-30 | 2014-12-04 | 大正製薬株式会社 | 坐剤 |
SMT202000472T1 (it) | 2013-08-19 | 2020-11-10 | Taris Biomedical Llc | Dispositivi di somministrazione di farmaco multi-unità |
WO2015070074A2 (en) | 2013-11-08 | 2015-05-14 | The Texas A &M University System | Porous microparticles with high loading efficiencies |
US20150238549A1 (en) * | 2014-02-27 | 2015-08-27 | Mak Wood, Inc. | Probiotic dosage units |
EP3113824B1 (en) | 2014-03-03 | 2021-04-14 | Cook Medical Technologies LLC | Mechanical dilator |
WO2015175545A1 (en) | 2014-05-12 | 2015-11-19 | The Johns Hopkins University | Highly stable biodegradable gene vector platforms for overcoming biological barriers |
JP7425534B2 (ja) | 2015-04-23 | 2024-01-31 | タリス バイオメディカル エルエルシー | 薬物透過性構成要素を有する薬物送達デバイス及び方法 |
CA2987520A1 (en) | 2015-05-29 | 2016-12-08 | Eve Pharma Ltd. | Ph-dependent vaginal compositions and methods of treatment of vaginal disorders |
RU2709464C2 (ru) | 2015-09-29 | 2019-12-18 | Кимберли-Кларк Ворлдвайд, Инк. | Синергическая композиция для сохранения здорового баланса микрофлоры |
KR101880179B1 (ko) * | 2016-11-03 | 2018-07-20 | 한국생명공학연구원 | 미카펀진(micafungin) 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 함유하는 항바이러스용 약학적 조성물 |
CN110799198A (zh) * | 2016-11-30 | 2020-02-14 | 普罗生物瑞士股份公司 | 用于稳定阴道液的酸度和氧化还原状态的基于合适的生化组合物的泌尿生殖器医疗设备制剂 |
US12029748B2 (en) | 2017-02-28 | 2024-07-09 | Kimberly-Clark Worldwide, Inc. | Synergistic composition for maintenance of healthy balance of microflora |
CA3123051A1 (en) * | 2018-12-19 | 2020-06-25 | Healthy Cow Corporation | Ready-to-use probiotic compositions and uses thereof |
US11529346B2 (en) * | 2020-06-18 | 2022-12-20 | National Medical Supply, LLC | Vaginal gel |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3988508A (en) * | 1973-03-08 | 1976-10-26 | Petrolite Corporation | High internal phase ratio emulsion polymers |
DE3321043A1 (de) * | 1983-06-10 | 1984-12-13 | Bayer Ag, 5090 Leverkusen | Antimykotische mittel fuer einmalige gynaekologische behandlung |
US4551148A (en) * | 1982-09-07 | 1985-11-05 | Kv Pharmaceutical Company | Vaginal delivery systems and their methods of preparation and use |
US5266329A (en) * | 1985-10-31 | 1993-11-30 | Kv Pharmaceutical Company | Vaginal delivery system |
US5536743A (en) * | 1988-01-15 | 1996-07-16 | Curatek Pharmaceuticals Limited Partnership | Intravaginal treatment of vaginal infections with buffered metronidazole compositions |
US4895452A (en) * | 1988-03-03 | 1990-01-23 | Micro-Pak, Inc. | Method and apparatus for producing lipid vesicles |
US5055303A (en) * | 1989-01-31 | 1991-10-08 | Kv Pharmaceutical Company | Solid controlled release bioadherent emulsions |
CA1337279C (en) | 1989-06-06 | 1995-10-10 | Robert J. Borgman | Intravaginal treatment of vaginal infections with buffered metronidazole compositions |
US5298246A (en) * | 1991-01-09 | 1994-03-29 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Stable pharmaceutical composition and method for its production |
DE69220317T2 (de) * | 1991-10-01 | 1997-10-16 | Takeda Chemical Industries Ltd | Mikropartikeln-Zusammenfassung zur verlängerten Freigabe und Herstellung derselbe |
US5189070A (en) * | 1992-05-29 | 1993-02-23 | Shell Oil Company | Process for preparing low density porous crosslinked polymeric materials |
US6191105B1 (en) * | 1993-05-10 | 2001-02-20 | Protein Delivery, Inc. | Hydrophilic and lipophilic balanced microemulsion formulations of free-form and/or conjugation-stabilized therapeutic agents such as insulin |
US5576016A (en) * | 1993-05-18 | 1996-11-19 | Pharmos Corporation | Solid fat nanoemulsions as drug delivery vehicles |
US5744155A (en) * | 1993-08-13 | 1998-04-28 | Friedman; Doron | Bioadhesive emulsion preparations for enhanced drug delivery |
US5470885A (en) * | 1993-09-29 | 1995-11-28 | The Research Foundation Of The State University Of New York | Fluorocarbons as anti-inflammatory agents |
TW438601B (en) * | 1994-05-18 | 2001-06-07 | Janssen Pharmaceutica Nv | New mucoadhesive emulsion compositions and a process for the preparation thereof |
US5980936A (en) * | 1997-08-07 | 1999-11-09 | Alliance Pharmaceutical Corp. | Multiple emulsions comprising a hydrophobic continuous phase |
US5877216A (en) * | 1997-10-28 | 1999-03-02 | Vivus, Incorporated | Treatment of female sexual dysfunction |
JP2001520999A (ja) * | 1997-10-28 | 2001-11-06 | アシビ, エルエルシー | 女性の性的機能不全の処置 |
US6899890B2 (en) * | 2002-03-20 | 2005-05-31 | Kv Pharmaceutical Company | Bioadhesive drug delivery system |
-
2002
- 2002-03-20 US US10/101,014 patent/US6899890B2/en not_active Expired - Lifetime
- 2002-06-28 CA CA002392473A patent/CA2392473C/en not_active Expired - Lifetime
- 2002-07-10 KR KR1020020039940A patent/KR20030076159A/ko not_active Application Discontinuation
- 2002-07-15 AU AU2002300175A patent/AU2002300175B2/en not_active Ceased
- 2002-07-15 MX MXPA02006943A patent/MXPA02006943A/es active IP Right Grant
- 2002-07-18 BR BR0202767-4A patent/BR0202767A/pt not_active IP Right Cessation
- 2002-07-26 IT IT2002MI001660A patent/ITMI20021660A1/it unknown
- 2002-07-29 CN CNA2007101048008A patent/CN101045034A/zh active Pending
- 2002-07-29 CN CN02127087A patent/CN1444926A/zh active Pending
- 2002-07-29 CN CN2010105156408A patent/CN102048689A/zh active Pending
- 2002-09-12 JP JP2002266381A patent/JP4462818B2/ja not_active Expired - Fee Related
- 2002-09-18 HU HU0203102A patent/HUP0203102A3/hu unknown
- 2002-10-15 PT PT102854A patent/PT102854B/pt not_active IP Right Cessation
- 2002-11-27 FR FR0214858A patent/FR2837389A1/fr active Pending
-
2003
- 2003-03-19 RU RU2004130870/15A patent/RU2320322C2/ru not_active IP Right Cessation
- 2003-03-19 AU AU2003218233A patent/AU2003218233A1/en not_active Abandoned
- 2003-03-19 WO PCT/US2003/008266 patent/WO2003079981A2/en not_active Application Discontinuation
- 2003-03-19 EP EP03714226A patent/EP1494630A4/en not_active Ceased
- 2003-03-20 AR ARP030100979A patent/AR039037A1/es unknown
-
2004
- 2004-09-17 ZA ZA200407535A patent/ZA200407535B/en unknown
-
2008
- 2008-10-29 KR KR1020080106637A patent/KR20080098576A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN102048689A (zh) | 2011-05-11 |
RU2320322C2 (ru) | 2008-03-27 |
JP4462818B2 (ja) | 2010-05-12 |
HUP0203102A2 (hu) | 2004-05-28 |
ZA200407535B (en) | 2006-06-28 |
AU2002300175A1 (en) | 2003-10-09 |
WO2003079981A3 (en) | 2003-11-06 |
AU2002300175B2 (en) | 2004-04-22 |
WO2003079981A2 (en) | 2003-10-02 |
HUP0203102A3 (en) | 2004-06-28 |
BR0202767A (pt) | 2004-05-25 |
AU2003218233A1 (en) | 2003-10-08 |
US6899890B2 (en) | 2005-05-31 |
CA2392473C (en) | 2007-09-18 |
CN101045034A (zh) | 2007-10-03 |
US20030180366A1 (en) | 2003-09-25 |
JP2003286193A (ja) | 2003-10-07 |
ITMI20021660A1 (it) | 2004-01-26 |
AU2003218233A8 (en) | 2003-10-08 |
KR20030076159A (ko) | 2003-09-26 |
CA2392473A1 (en) | 2003-09-20 |
CN1444926A (zh) | 2003-10-01 |
HU0203102D0 (es) | 2002-11-28 |
RU2004130870A (ru) | 2005-06-10 |
PT102854A (pt) | 2003-09-30 |
MXPA02006943A (es) | 2004-12-13 |
EP1494630A4 (en) | 2007-03-14 |
FR2837389A1 (fr) | 2003-09-26 |
PT102854B (pt) | 2004-02-27 |
KR20080098576A (ko) | 2008-11-11 |
EP1494630A2 (en) | 2005-01-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR039037A1 (es) | Un sistema de liberacion de una droga vaginal con un ph esencialmente neutro y un metodo para tratar una enfermedad vaginal que comprende dicho sistema | |
JP5435955B2 (ja) | 安定な酵素製剤及びその使用方法 | |
US5750141A (en) | Administration of vaso-active agent and therapeutic agent | |
AR044547A1 (es) | Sistema de distribucion de drogas | |
ECSP056076A (es) | Sistema de suministro para droga y terapia celular | |
AR047039A1 (es) | Sistema y metodo para administracion transdermica | |
BR0008058A (pt) | Forma de estado sólido de celecoxib tendo biodisposnibilidade melhorada | |
AR049985A1 (es) | Tratamiento de combinacion para enfermedades malignas no hematologicas | |
AR032293A1 (es) | Estuche farmaceutico | |
Feldman et al. | Current drug therapies for rosacea: a chronic vascular and inflammatory skin disease | |
CY1110078T1 (el) | Παρασκευασματα με ιωδιουχο ποβιδονη για την αγωγη τραυματων | |
BRPI0513673B8 (pt) | método para produzir um medicamento para aumentar a eficácia e o transporte dos compostos biologicamente ativos enteralmente administrados, e composição farmacêutica | |
BR0315461A (pt) | Sistema terapêutico em forma de pelìcula e processo para a terapia ou para a profilaxia medicinal | |
BR0210994A (pt) | Compostos farmacêuticos e de diagnósticos contendo nanopartìculas úteis para tratamento de tecidos e células | |
Timmons et al. | The use of negative‐pressure wound therapy to manage enteroatmospheric fistulae in two patients with large abdominal wounds | |
ATE206043T1 (de) | Örtliche arzneistoffabgabe in tieferen magendarmtraktabschnitten | |
Marks et al. | Pretreatment with allopurinol diminishes pancreatography-induced pancreatitis in a canine model | |
CR8059A (es) | Composicion farmaceutica en forma de hidrogel para administracion transdermica de sustancias activas | |
Cavallini | Minoxidil versus nitroglycerine: a prospective, double-blind, controlled trial in transcutaneous therapy for organic impotence | |
FR2872702B3 (fr) | Systeme de delivrance | |
RU2006119263A (ru) | Способ лечения больных розацеа | |
AR062894A1 (es) | Formulaciones para administracion terapeutica de hormona de estimulacion del tiroides (ths) | |
RU2321410C1 (ru) | Способ лечения воспалительных процессов | |
CN101401782A (zh) | 多拉菌素浇泼剂及其制备方法 | |
RU2630615C1 (ru) | Способ консервативного лечения острого геморроя |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |