AR021922A1 - Formulaciones farmaceuticas en aerosol que contienen fluoroalcanos, budesonido y formoterol. - Google Patents
Formulaciones farmaceuticas en aerosol que contienen fluoroalcanos, budesonido y formoterol.Info
- Publication number
- AR021922A1 AR021922A1 ARP990106573A ARP990106573A AR021922A1 AR 021922 A1 AR021922 A1 AR 021922A1 AR P990106573 A ARP990106573 A AR P990106573A AR P990106573 A ARP990106573 A AR P990106573A AR 021922 A1 AR021922 A1 AR 021922A1
- Authority
- AR
- Argentina
- Prior art keywords
- formoterol
- fluoroalcans
- budesonido
- pharmaceutical formulations
- aerosol containing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/124—Aerosols; Foams characterised by the propellant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C66/00—General aspects of processes or apparatus for joining preformed parts
- B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
- B29C66/71—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the composition of the plastics material of the parts to be joined
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se provee una formulacion en solucion en aerosol adaptada para ser utilizada en un aerosol presurizado. La formulacion en aerosol se prepara a partir deuna composicion que contiene Budesonido, formoterol, al menos un propelente fluoroalcano, y un cosolvente presente en una cantidad que disuelve o solubilizadichos Budesonido y Formoterol en la mezcla de cosolvente y propelente.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/215,280 US6004537A (en) | 1998-12-18 | 1998-12-18 | Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol |
Publications (1)
Publication Number | Publication Date |
---|---|
AR021922A1 true AR021922A1 (es) | 2002-09-04 |
Family
ID=22802357
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990106573A AR021922A1 (es) | 1998-12-18 | 1999-12-20 | Formulaciones farmaceuticas en aerosol que contienen fluoroalcanos, budesonido y formoterol. |
Country Status (12)
Country | Link |
---|---|
US (1) | US6004537A (es) |
EP (1) | EP1140059A2 (es) |
JP (1) | JP4921639B2 (es) |
AR (1) | AR021922A1 (es) |
AU (1) | AU776257B2 (es) |
BR (1) | BR9916829A (es) |
CA (1) | CA2355932C (es) |
CZ (1) | CZ20012216A3 (es) |
HU (1) | HUP0200014A3 (es) |
PL (1) | PL348809A1 (es) |
TW (1) | TW574038B (es) |
WO (1) | WO2000035441A2 (es) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4003272A1 (de) * | 1990-02-03 | 1991-08-08 | Boehringer Ingelheim Kg | Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen |
DK0835098T3 (da) * | 1995-06-27 | 2002-10-07 | Boehringer Ingelheim Pharma | Stabilt lægemiddelpræparat til frembringlese af drivgasfrie aerosoler |
GB9616237D0 (en) | 1996-08-01 | 1996-09-11 | Norton Healthcare Ltd | Aerosol formulations |
US20010031244A1 (en) * | 1997-06-13 | 2001-10-18 | Chiesi Farmaceutici S.P.A. | Pharmaceutical aerosol composition |
SE9703407D0 (sv) | 1997-09-19 | 1997-09-19 | Astra Ab | New use |
SE9802073D0 (sv) | 1998-06-11 | 1998-06-11 | Astra Ab | New use |
US6451285B2 (en) * | 1998-06-19 | 2002-09-17 | Baker Norton Pharmaceuticals, Inc. | Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant |
DZ2947A1 (fr) * | 1998-11-25 | 2004-03-15 | Chiesi Farma Spa | Inhalateur à compteur de dose sous pression. |
IT1303788B1 (it) * | 1998-11-25 | 2001-02-23 | Chiesi Farma Spa | Formulazioni di aerosol medicinali. |
US6290930B1 (en) * | 1998-12-18 | 2001-09-18 | Baker Norton Pharmaceuticals, Inc. | Pharmaceutical solution aerosol formulations containing fluoroalkanes and budesonide |
US6315985B1 (en) * | 1999-06-18 | 2001-11-13 | 3M Innovative Properties Company | C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability |
IT1313553B1 (it) * | 1999-07-23 | 2002-09-09 | Chiesi Farma Spa | Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione. |
IT1317904B1 (it) * | 1999-09-11 | 2003-07-15 | Glaxo Group Ltd | Formulazione farmaceutica di propionato di fluticasone. |
US20030032632A1 (en) * | 1999-12-24 | 2003-02-13 | Crispps Leslie Alan | Pharmaceutical aerosol formulation of salmeterol and fluticasone propionate |
IT1317720B1 (it) * | 2000-01-07 | 2003-07-15 | Chiesi Farma Spa | Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani. |
IT1317846B1 (it) | 2000-02-22 | 2003-07-15 | Chiesi Farma Spa | Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva. |
GB0009584D0 (en) * | 2000-04-18 | 2000-06-07 | Glaxo Group Ltd | Pharmaceutical compositions |
IT1318514B1 (it) * | 2000-05-12 | 2003-08-27 | Chiesi Farma Spa | Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari. |
US20060257324A1 (en) * | 2000-05-22 | 2006-11-16 | Chiesi Farmaceutici S.P.A. | Pharmaceutical solution formulations for pressurised metered dose inhalers |
UA73986C2 (uk) * | 2000-05-22 | 2005-10-17 | К'Єзі Фармачеутічі С.П.А. | АЕРОЗОЛЬНА КОМПОЗИЦІЯ, ЩО МІСТИТЬ <font face="Symbol">b</font>2-АДРЕНЕРГІЧНИЙ АГОНІСТ ТРИВАЛОЇ ДІЇ, ДОЗУЮЧИЙ ІНГАЛЯТОР ПІД ТИСКОМ ТА СПОСІБ ЙОГО ЗАПОВНЕННЯ |
US20030055026A1 (en) | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
US6667344B2 (en) | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
ES2222294T3 (es) * | 2001-07-02 | 2005-02-01 | Chiesi Farmaceutici S.P.A. | Formulacion optimizada de tobramicina para administracion en forma de aerosol. |
SE0200312D0 (sv) | 2002-02-01 | 2002-02-01 | Astrazeneca Ab | Novel composition |
WO2003074024A1 (en) * | 2002-03-01 | 2003-09-12 | Chiesi Farmaceutici S.P.A | Formoterol superfine formulation |
GB0207899D0 (en) * | 2002-04-05 | 2002-05-15 | 3M Innovative Properties Co | Formoterol and cielesonide aerosol formulations |
PT1542904E (pt) * | 2002-08-27 | 2008-03-24 | Schering Corp | Processo para produzir formulações para inaladores doseadores |
SE0203376D0 (sv) * | 2002-11-15 | 2002-11-15 | Astrazeneca Ab | New process |
TWI359675B (en) * | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
AR041873A1 (es) * | 2003-10-30 | 2005-06-01 | Pablo Cassara Srl Lab | Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante |
EP1595531A1 (en) | 2004-05-13 | 2005-11-16 | CHIESI FARMACEUTICI S.p.A. | Stable pharmaceutical solution formulations for pressurized metered dose inhalers |
TWI558685B (zh) * | 2005-06-24 | 2016-11-21 | 哈尼威爾國際公司 | 含有經氟取代之烯烴之組合物 |
GB0604141D0 (en) * | 2006-03-01 | 2006-04-12 | Arrow Int Ltd | Nebulizer formulation |
EP2117504A1 (en) * | 2007-02-09 | 2009-11-18 | Schering Corporation | Stable pharmaceutical drug aerosols |
US20100055045A1 (en) * | 2008-02-26 | 2010-03-04 | William Gerhart | Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations |
WO2009134524A2 (en) * | 2008-02-26 | 2009-11-05 | Elevation Pharmaceuticals, Inc. | Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations |
JP5873013B2 (ja) | 2009-05-29 | 2016-03-01 | パール セラピューティクス,インコーポレイテッド | 2つ以上の活性剤を呼吸器送達するための組成物、方法および系 |
EP2512438B1 (en) | 2009-12-16 | 2017-01-25 | 3M Innovative Properties Company | Formulations and methods for controlling mdi particle size delivery |
TWI399202B (zh) | 2011-03-17 | 2013-06-21 | Intech Biopharm Ltd | 製備用於治療呼吸道疾病之定量噴霧吸入劑的製程方法 |
CN102362860A (zh) * | 2011-10-27 | 2012-02-29 | 江阴长风医药科技有限公司 | 以氢氟烷烃为抛射剂的布地奈德和福莫特罗气雾剂制剂 |
ITMI20130571A1 (it) | 2013-04-10 | 2014-10-11 | Zambon Spa | Composizione farmaceutica contenente budesonide e formoterolo |
KR102277635B1 (ko) | 2016-09-19 | 2021-07-19 | 멕시켐 플루어 소시에다드 아노니마 데 카피탈 바리아블레 | 약제학적 조성물 |
JP7268965B2 (ja) * | 2018-06-05 | 2023-05-08 | アース製薬株式会社 | 定量噴射型エアゾール製品および消臭方法 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7708731A (nl) * | 1976-08-13 | 1978-02-15 | Montedison Spa | Werkwijze voor de bereiding van nieuwe drijf- middelsamenstellingen voor aerosolen. |
US5225183A (en) * | 1988-12-06 | 1993-07-06 | Riker Laboratories, Inc. | Medicinal aerosol formulations |
MX9203481A (es) * | 1990-10-18 | 1992-07-01 | Minnesota Mining & Mfg | Formulaciones. |
CA2094266C (en) * | 1990-10-18 | 1999-06-01 | Robert K. Schultz | Aerosol formulations of beclomethasone-17,21-dipropionate |
US5190029A (en) * | 1991-02-14 | 1993-03-02 | Virginia Commonwealth University | Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content |
WO1992022286A1 (en) * | 1991-06-12 | 1992-12-23 | Minnesota Mining And Manufacturing Company | Albuterol sulfate suspension aerosol formulations |
DE4123663A1 (de) * | 1991-07-17 | 1993-01-21 | Schwabe Willmar Gmbh & Co | Aerosol-zubereitung und verwendung eines treibmittels dafuer |
US5683676A (en) * | 1991-12-12 | 1997-11-04 | Glaxo Group Limited | Canister containing aerosol formulations containing P134a and particulate medicaments |
US5674471A (en) * | 1991-12-12 | 1997-10-07 | Glaxo Group Limited | Aerosol formulations containing P134a and salbutamol |
ATE213946T1 (de) * | 1991-12-18 | 2002-03-15 | Formoterol und budesonide enthaltende zusammensetzung | |
ATE137666T1 (de) * | 1991-12-31 | 1996-05-15 | Hoechst Ag | Medizinische aerosolformulierung |
GB9612297D0 (en) * | 1996-06-11 | 1996-08-14 | Minnesota Mining & Mfg | Medicinal aerosol formulations |
GB9616237D0 (en) * | 1996-08-01 | 1996-09-11 | Norton Healthcare Ltd | Aerosol formulations |
SE9603669D0 (sv) * | 1996-10-08 | 1996-10-08 | Astra Ab | New combination |
SE9703407D0 (sv) * | 1997-09-19 | 1997-09-19 | Astra Ab | New use |
SE9802073D0 (sv) * | 1998-06-11 | 1998-06-11 | Astra Ab | New use |
-
1998
- 1998-12-18 US US09/215,280 patent/US6004537A/en not_active Expired - Fee Related
-
1999
- 1999-12-17 JP JP2000587761A patent/JP4921639B2/ja not_active Expired - Fee Related
- 1999-12-17 BR BR9916829-4A patent/BR9916829A/pt not_active Application Discontinuation
- 1999-12-17 WO PCT/US1999/030163 patent/WO2000035441A2/en not_active Application Discontinuation
- 1999-12-17 HU HU0200014A patent/HUP0200014A3/hu not_active Application Discontinuation
- 1999-12-17 EP EP99966403A patent/EP1140059A2/en not_active Withdrawn
- 1999-12-17 CA CA002355932A patent/CA2355932C/en not_active Expired - Fee Related
- 1999-12-17 PL PL99348809A patent/PL348809A1/xx not_active Application Discontinuation
- 1999-12-17 CZ CZ20012216A patent/CZ20012216A3/cs unknown
- 1999-12-17 AU AU21949/00A patent/AU776257B2/en not_active Ceased
- 1999-12-20 AR ARP990106573A patent/AR021922A1/es not_active Application Discontinuation
-
2000
- 2000-06-01 TW TW88122054A patent/TW574038B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2355932C (en) | 2009-06-23 |
BR9916829A (pt) | 2001-10-23 |
PL348809A1 (en) | 2002-06-17 |
EP1140059A2 (en) | 2001-10-10 |
WO2000035441A2 (en) | 2000-06-22 |
CZ20012216A3 (cs) | 2002-04-17 |
JP2002532418A (ja) | 2002-10-02 |
HUP0200014A3 (en) | 2005-06-28 |
US6004537A (en) | 1999-12-21 |
AU2194900A (en) | 2000-07-03 |
AU776257B2 (en) | 2004-09-02 |
CA2355932A1 (en) | 2000-06-22 |
TW574038B (en) | 2004-02-01 |
HUP0200014A2 (hu) | 2002-06-29 |
WO2000035441A3 (en) | 2000-10-26 |
JP4921639B2 (ja) | 2012-04-25 |
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Legal Events
Date | Code | Title | Description |
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FA | Abandonment or withdrawal | ||
FC | Refusal |