AR013801A1 - Nuevas moleculas de acido nucleico aislada, una proteina de epoxido hidrolasa de artropodo hematofago aislada, una formulacion de proteinas deepoxido hidrolasa de pulga, una composicion terapeutica que reduce la infestacion de ectoparasitos hematofagos; uso de dicha composicion para la - Google Patents
Nuevas moleculas de acido nucleico aislada, una proteina de epoxido hidrolasa de artropodo hematofago aislada, una formulacion de proteinas deepoxido hidrolasa de pulga, una composicion terapeutica que reduce la infestacion de ectoparasitos hematofagos; uso de dicha composicion para laInfo
- Publication number
- AR013801A1 AR013801A1 ARP980106307A ARP980106307A AR013801A1 AR 013801 A1 AR013801 A1 AR 013801A1 AR P980106307 A ARP980106307 A AR P980106307A AR P980106307 A ARP980106307 A AR P980106307A AR 013801 A1 AR013801 A1 AR 013801A1
- Authority
- AR
- Argentina
- Prior art keywords
- seq
- hydrolasse
- nucleic acid
- proteins
- isolated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Una molécula de ácido nucleico aislada que híbrida bajo condiciones de hibridacion severas con un gen que comprende una secuencia de ácido nucleicoseleccionada entre el grupo que consiste de SEC ID NO: 4, SEC ID NO; 6, SEC ID NO:7, SEC ID NO:9,SEC ID NO:10, SEC ID NO:12, SEC ID NO:15, SEC ID NO:19, SECID NO:21, SEC ID NO:22, SEC ID NO:24, SEC ID NO:25, SEC ID NO:26 y SEC ID NO: 27. Una molécula de ácido nucleico aislada que hibrida bajo condiciones dehibridacion severas con un complemento de una molécula de ácido nucleico que tiene una secuencia de ácido nucleico que codifica una proteína que comprendeuna secuencia de aminoácidos seleccionada entre el grupo que consiste de SEC ID NO:5, SEC ID NO:8, SEC ID NO:11, SEC ID NO:20, SEC ID NO:23 y SEC ID NO:28.Además se describen proteínas de epoxido hidrolasa de artopodo, con moléculas de ácido nucleico de epoxido hidrolasa de artropodo, inlcuyendo aquellas quecodifican dichas proteínas de epoxido hidrolasa; con anticuerpos producidos contra dichas proteínas de epoxido hidrolasa; y con otros compuestos queinhiben la actividad de epoxido hidrolasa de artropodo. Además incluye métodos para obtener dichas proteínas, moléculas de ácido nucleico, anticuerpos ycompuestos inhibitorios. Además se incluyen composiciones terapéuticas que comprenden dichas proteínas, moléculas de ácido nucleico, anticuerpos y/ocompuestos inhibitorios, así como también el uso de dichas composiciones terapéuticas para la fabricacion de medicamentos contra la infestacion deartropodoshematofagos en animales.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/989,510 US6037160A (en) | 1997-12-12 | 1997-12-12 | Flea epoxide hydrolase nucleic acid molecules, proteins and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
AR013801A1 true AR013801A1 (es) | 2001-01-10 |
Family
ID=25535175
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP980106307A AR013801A1 (es) | 1997-12-12 | 1998-12-11 | Nuevas moleculas de acido nucleico aislada, una proteina de epoxido hidrolasa de artropodo hematofago aislada, una formulacion de proteinas deepoxido hidrolasa de pulga, una composicion terapeutica que reduce la infestacion de ectoparasitos hematofagos; uso de dicha composicion para la |
Country Status (5)
Country | Link |
---|---|
US (4) | US6037160A (es) |
AR (1) | AR013801A1 (es) |
AU (1) | AU1818399A (es) |
WO (1) | WO1999031253A2 (es) |
ZA (1) | ZA9811354B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6891085B2 (en) * | 2001-04-20 | 2005-05-10 | Pioneer Hi-Bred International, Inc. | Nucleic acid encoding the FUS6 antimicrobial polypeptide of Agrotis ipsilon and its use to enhance disease resistance in a plant |
US7612194B2 (en) | 2001-07-24 | 2009-11-03 | Monsanto Technology Llc | Nucleic acid sequences from Diabrotica virgifera virgifera LeConte and uses thereof |
US6943001B2 (en) * | 2001-08-03 | 2005-09-13 | Diversa Corporation | Epoxide hydrolases, nucleic acids encoding them and methods for making and using them |
WO2003012126A2 (en) * | 2001-08-03 | 2003-02-13 | Diversa Corporation | Epoxide hydrolases, nucleic acids encoding them and methods for making and using them |
NZ533657A (en) * | 2002-01-03 | 2008-01-31 | Smithkline Beecham Corp | Methods for the preparation of immunoconjugates, in particular maytansinoids conjugated to a monoclonal antibody |
CA2562022C (en) | 2004-04-09 | 2016-01-26 | Monsanto Technology Llc | Compositions and methods for control of insect infestations in plants |
EP3173486B1 (en) | 2005-09-16 | 2019-02-13 | Monsanto Technology LLC | Methods for genetic control of insect infestations in plants and compositions thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69214518T2 (de) * | 1991-05-31 | 1997-03-20 | Sandoz Ag | Methode zur Bekämpfung von Flöhen |
US5445956A (en) * | 1993-08-13 | 1995-08-29 | The Regents Of The University Of California | Recombinant soluble epoxide hydrolase |
-
1997
- 1997-12-12 US US08/989,510 patent/US6037160A/en not_active Expired - Lifetime
-
1998
- 1998-10-29 US US09/182,816 patent/US6143542A/en not_active Expired - Lifetime
- 1998-12-10 AU AU18183/99A patent/AU1818399A/en not_active Abandoned
- 1998-12-10 ZA ZA9811354A patent/ZA9811354B/xx unknown
- 1998-12-10 WO PCT/US1998/026359 patent/WO1999031253A2/en active Application Filing
- 1998-12-11 AR ARP980106307A patent/AR013801A1/es unknown
-
1999
- 1999-12-27 US US09/471,528 patent/US6153397A/en not_active Expired - Lifetime
-
2000
- 2000-08-08 US US09/634,530 patent/US6290958B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6153397A (en) | 2000-11-28 |
US6290958B1 (en) | 2001-09-18 |
ZA9811354B (en) | 1999-06-10 |
US6143542A (en) | 2000-11-07 |
US6037160A (en) | 2000-03-14 |
WO1999031253A2 (en) | 1999-06-24 |
WO1999031253A3 (en) | 1999-09-16 |
AU1818399A (en) | 1999-07-05 |
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