AP2000001787A0 - Use of thiazolidinediones for the treatment of hyperglycaemia. - Google Patents

Use of thiazolidinediones for the treatment of hyperglycaemia.

Info

Publication number: AP2000001787A0
Authority: AP; ARIPO
Prior art keywords: hyperglycaemia; treatment; thiazolidinediones; efective; mammal
Prior art date: 1997-10-13

Application number

APAP/P/2000/001787A

Other languages

English (en)

Inventor

Robin Edwin Buckingham

Stephen Alistair Smith

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-10-13

Filing date

1998-10-12

Publication date

2000-06-30

1998-10-12 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

2000-06-30 Publication of AP2000001787A0 publication Critical patent/AP2000001787A0/en

Links

201000001421 hyperglycemia Diseases 0.000 title abstract 2
229940123464 Thiazolidinedione Drugs 0.000 title 1
150000001467 thiazolidinediones Chemical class 0.000 title 1
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
102000004877 Insulin Human genes 0.000 abstract 1
108090001061 Insulin Proteins 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
239000008103 glucose Substances 0.000 abstract 1
229940125396 insulin Drugs 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
231100000489 sensitizer Toxicity 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
Emergency Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

APAP/P/2000/001787A 1997-10-13 1998-10-12 Use of thiazolidinediones for the treatment of hyperglycaemia. AP2000001787A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9721693.1A GB9721693D0 (en)	1997-10-13	1997-10-13	Novel treatment
PCT/GB1998/003064 WO1999018943A1 (en)	1997-10-13	1998-10-12	Use of thiazolidinediones for the treatment of hyperglycaemia

Publications (1)

Publication Number	Publication Date
AP2000001787A0 true AP2000001787A0 (en)	2000-06-30

Family

ID=10820482

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
APAP/P/2000/001787A AP2000001787A0 (en)	1997-10-13	1998-10-12	Use of thiazolidinediones for the treatment of hyperglycaemia.

Country Status (24)

Country	Link
EP (1)	EP1023056A1 (ru)
JP (1)	JP2001519382A (ru)
KR (1)	KR20010024481A (ru)
CN (1)	CN1281359A (ru)
AP (1)	AP2000001787A0 (ru)
AU (1)	AU9547098A (ru)
BG (1)	BG104404A (ru)
BR (1)	BR9815219A (ru)
CA (1)	CA2306086A1 (ru)
CZ (1)	CZ20001297A3 (ru)
EA (1)	EA002659B1 (ru)
GB (1)	GB9721693D0 (ru)
HR (1)	HRP20000255A2 (ru)
HU (1)	HUP0003922A3 (ru)
ID (1)	ID24521A (ru)
IL (1)	IL135513A0 (ru)
NO (1)	NO20001898L (ru)
NZ (1)	NZ503862A (ru)
OA (1)	OA11683A (ru)
PL (1)	PL339813A1 (ru)
SK (1)	SK5312000A3 (ru)
TR (1)	TR200000958T2 (ru)
WO (1)	WO1999018943A1 (ru)
YU (1)	YU28800A (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7045519B2 (en)	1998-06-19	2006-05-16	Chiron Corporation	Inhibitors of glycogen synthase kinase 3

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2137915T3 (es) *	1987-09-04	2000-01-01	Beecham Group Plc	Derivados de tiazolidindiona sustituida.
GB9218830D0 (en) *	1992-09-05	1992-10-21	Smithkline Beecham Plc	Novel compounds
US5478852C1 (en) *	1993-09-15	2001-03-13	Sankyo Co	Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus

1997
- 1997-10-13 GB GBGB9721693.1A patent/GB9721693D0/en not_active Ceased
1998
- 1998-10-12 CZ CZ20001297A patent/CZ20001297A3/cs unknown
- 1998-10-12 WO PCT/GB1998/003064 patent/WO1999018943A1/en not_active Application Discontinuation
- 1998-10-12 IL IL13551398A patent/IL135513A0/xx unknown
- 1998-10-12 EP EP98949086A patent/EP1023056A1/en not_active Withdrawn
- 1998-10-12 PL PL98339813A patent/PL339813A1/xx unknown
- 1998-10-12 OA OA1200000108A patent/OA11683A/en unknown
- 1998-10-12 NZ NZ503862A patent/NZ503862A/xx unknown
- 1998-10-12 TR TR2000/00958T patent/TR200000958T2/xx unknown
- 1998-10-12 AU AU95470/98A patent/AU9547098A/en not_active Abandoned
- 1998-10-12 YU YU28800A patent/YU28800A/sh unknown
- 1998-10-12 AP APAP/P/2000/001787A patent/AP2000001787A0/en unknown
- 1998-10-12 SK SK531-2000A patent/SK5312000A3/sk unknown
- 1998-10-12 KR KR1020007003934A patent/KR20010024481A/ko not_active Application Discontinuation
- 1998-10-12 ID IDW20000669A patent/ID24521A/id unknown
- 1998-10-12 EA EA200000419A patent/EA002659B1/ru not_active IP Right Cessation
- 1998-10-12 HU HU0003922A patent/HUP0003922A3/hu unknown
- 1998-10-12 JP JP2000515578A patent/JP2001519382A/ja active Pending
- 1998-10-12 CA CA002306086A patent/CA2306086A1/en not_active Abandoned
- 1998-10-12 BR BR9815219-0A patent/BR9815219A/pt not_active Application Discontinuation
- 1998-10-12 CN CN98812083A patent/CN1281359A/zh active Pending
2000
- 2000-04-12 NO NO20001898A patent/NO20001898L/no not_active Application Discontinuation
- 2000-05-02 HR HR20000255A patent/HRP20000255A2/hr not_active Application Discontinuation
- 2000-05-05 BG BG104404A patent/BG104404A/bg unknown

Also Published As

Publication number	Publication date
NO20001898D0 (no)	2000-04-12
EA002659B1 (ru)	2002-08-29
PL339813A1 (en)	2001-01-02
IL135513A0 (en)	2001-05-20
ID24521A (id)	2000-07-20
SK5312000A3 (en)	2000-09-12
NZ503862A (en)	2003-01-31
KR20010024481A (ko)	2001-03-26
CZ20001297A3 (cs)	2001-08-15
BG104404A (bg)	2000-12-29
BR9815219A (pt)	2001-01-02
HRP20000255A2 (en)	2001-02-28
CA2306086A1 (en)	1999-04-22
HUP0003922A2 (hu)	2001-10-28
EP1023056A1 (en)	2000-08-02
YU28800A (sh)	2003-02-28
AU9547098A (en)	1999-05-03
EA200000419A1 (ru)	2000-10-30
TR200000958T2 (tr)	2000-08-21
WO1999018943A1 (en)	1999-04-22
JP2001519382A (ja)	2001-10-23
HUP0003922A3 (en)	2001-12-28
CN1281359A (zh)	2001-01-24
GB9721693D0 (en)	1997-12-10
OA11683A (en)	2005-01-12
NO20001898L (no)	2000-06-09

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