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English
Failure of Bcl-2 family members to interact with Apaf-1 in normal and apoptotic cells
scientific article published on 01 October 2000
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11279541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
title
Failure of Bcl-2 family members to interact with Apaf-1 in normal and apoptotic cells
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11279541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
main subject
apoptotic process
1 reference
based on heuristic
inferred from title
author name string
Conus S
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11279541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
Rossé T
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11279541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
Borner C
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11279541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
publication date
1 October 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11279541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
published in
Cell Death & Differentiation
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11279541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
volume
7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11279541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
issue
10
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11279541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
page(s)
947-954
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11279541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
cites work
Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell Death in Development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction and regulation of the Caenorhabditis elegans death protease CED-3 by CED-4 and CED-9.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of CED-4 in the activation of CED-3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caenorhabditis elegans CED-4 stimulates CED-3 processing and CED-3-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role of CED-4 oligomerization in CED-3 activation and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis CED-4 is a stranger no more
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian caspases: structure, activation, substrates, and functions during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase structure, proteolytic substrates, and function during apoptotic cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms mediating caspase activation in cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apaf1 and the apoptotic machinery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondria and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Bcl-2 protein family: arbiters of cell survival
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 family proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2-family proteins: the role of the BH3 domain in apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 overexpression blocks activation of the death protease CPP32/Yama/apopain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction and regulation of subcellular localization of CED-4 by CED-9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-x(L) forms an ion channel in synthetic lipid membranes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Channel formation by antiapoptotic protein Bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonionic detergents induce dimerization among members of the Bcl-2 family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The binding properties and biological activities of Bcl-2 and Bax in cells exposed to apoptotic stimuli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between the C. elegans cell-death regulators CED-9 and CED-4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-xL does not inhibit the function of Apaf-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400729
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.CDD.4400729
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11279541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
PubMed publication ID
11279541
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11279541
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11279541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
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