(Q54979703)

PubMed publication ID

29729422

14 June 2018

http://europepmc.org/abstract/MED/29729422

1 reference

29 December 2023

https://doi.org/10.1016/j.neurobiolaging.2021.04.004

http://retractionwatch.com/2020/09/10/arizona-state-investigating-data-anomalies-in-work-by-two-former-neuroscience-faculty-members/

title

Genetically reducing mTOR signaling rescues central insulin dysregulation in a mouse model of Alzheimer's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6777740&resulttype=core&format=json

12 May 2020

0 references

Antonella Caccamo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6777740&resulttype=core&format=json

12 May 2020

Ramona Belfiore

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6777740&resulttype=core&format=json

12 May 2020

Salvatore Oddo

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6777740&resulttype=core&format=json

12 May 2020

publication date

5 April 2018

1 reference

PubMed publication ID

29729422

14 June 2018

http://europepmc.org/abstract/MED/29729422

published in

Neurobiology of Aging

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6777740&resulttype=core&format=json

12 May 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6777740&resulttype=core&format=json

12 May 2020

page(s)

59-67

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6777740&resulttype=core&format=json

The role of the tyrosine kinase domain of the insulin-like growth factor-I receptor in intracellular signaling, cellular proliferation, and tumorigenesis

12 May 2020

cites work

1 reference

12 December 2020

1 reference

12 December 2020

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

12 December 2020

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1 reference

12 December 2020

Attention and executive deficits in Alzheimer's disease. A critical review

1 reference

12 December 2020

Diabetes mellitus and the risk of dementia: The Rotterdam Study.

1 reference

12 December 2020

Insulin receptors and insulin action in the brain: review and clinical implications

1 reference

12 December 2020

Phosphorylation of eukaryotic initiation factor-2alpha (eIF2alpha) is associated with neuronal degeneration in Alzheimer's disease

1 reference

12 December 2020

Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease

1 reference

12 December 2020

Homogeneity and heterogeneity in mild cognitive impairment and Alzheimer's disease: a cross-sectional and longitudinal study of 55 cases

1 reference

12 December 2020

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

1 reference

12 December 2020

Insulin resistance contributes to aberrant stress responses in the Tg2576 mouse model of Alzheimer's disease

1 reference

12 December 2020

Microglia as a potential bridge between the amyloid beta-peptide and tau.

1 reference

12 December 2020

Positive and negative regulation of insulin signaling through IRS-1 phosphorylation

1 reference

12 December 2020

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?

1 reference

12 December 2020

mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes

1 reference

12 December 2020

TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model.

1 reference

12 December 2020

Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1.

1 reference

12 December 2020

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

1 reference

12 December 2020

PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding

1 reference

12 December 2020

The role of inflammatory cytokines in diabetes and its complications

1 reference

12 December 2020

p70 S6 kinase and tau in Alzheimer's disease.

1 reference

12 December 2020

Phosphorylation of IRS proteins, insulin action, and insulin resistance

1 reference

12 December 2020

mTOR-dependent signalling in Alzheimer's disease

1 reference

12 December 2020

Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease

1 reference

12 December 2020

1 reference

12 December 2020

Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments

1 reference

12 December 2020

Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucine

1 reference

12 December 2020

Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status

1 reference

12 December 2020

How does diabetes accelerate Alzheimer disease pathology?

1 reference

12 December 2020

Functions and regulation of the 70kDa ribosomal S6 kinases.

1 reference

12 December 2020

Naturally secreted amyloid-beta increases mammalian target of rapamycin (mTOR) activity via a PRAS40-mediated mechanism

1 reference

12 December 2020

GSK3 and Alzheimer's Disease: Facts and Fiction….

1 reference

12 December 2020

Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits

1 reference

12 December 2020

Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

1 reference

12 December 2020

Contributions of brain insulin resistance and deficiency in amyloid-related neurodegeneration in Alzheimer's disease

1 reference

12 December 2020

The role of mTOR signaling in Alzheimer disease

1 reference

12 December 2020

Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

1 reference

12 December 2020

mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies.

1 reference

12 December 2020

Autophagic/lysosomal dysfunction in Alzheimer's disease

1 reference

12 December 2020

GSK3 in Alzheimer's disease: mind the isoforms

1 reference

12 December 2020

Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology

1 reference

12 December 2020

Genetic reduction of mammalian target of rapamycin ameliorates Alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signature

1 reference

12 December 2020

GSK-3β, a pivotal kinase in Alzheimer disease.

1 reference

12 December 2020

Administration of a selective β2 adrenergic receptor antagonist exacerbates neuropathology and cognitive deficits in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Age-dependent impairment of glucose tolerance in the 3xTg-AD mouse model of Alzheimer's disease

1 reference

12 December 2020

Prevalence of and Trends in Diabetes Among Adults in the United States, 1988-2012.

1 reference

12 December 2020

Reducing Ribosomal Protein S6 Kinase 1 Expression Improves Spatial Memory and Synaptic Plasticity in a Mouse Model of Alzheimer's Disease

1 reference

12 December 2020

Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology

1 reference

12 December 2020

Cognitive Decline in a Colombian Kindred With Autosomal Dominant Alzheimer Disease: A Retrospective Cohort Study

1 reference

12 December 2020

Insights on the pathophysiology of Alzheimer's disease: The crosstalk between amyloid pathology, neuroinflammation and the peripheral immune system

1 reference

12 December 2020

Is Alzheimer's disease a Type 3 Diabetes? A critical appraisal

1 reference

12 December 2020

2016 Alzheimer's disease facts and figures

1 reference

12 December 2020

p62 improves AD-like pathology by increasing autophagy

1 reference

12 December 2020

Targeting mTOR to reduce Alzheimer-related cognitive decline: from current hits to future therapies

1 reference

12 December 2020

Insulin resistance in Alzheimer's disease

1 reference

12 December 2020

mTOR Signaling in Growth, Metabolism, and Disease.

1 reference

12 December 2020

The mTOR Signaling Pathway in Myocardial Dysfunction in Type 2 Diabetes Mellitus

1 reference

12 December 2020

Type 2 diabetes and quality of life

1 reference

12 December 2020

Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease

1 reference

12 December 2020

The mammalian target of rapamycin at the crossroad between cognitive aging and Alzheimer's disease

1 reference

12 December 2020

10.1016/J.NEUROBIOLAGING.2018.03.032

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6777740&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6777740&resulttype=core&format=json

12 May 2020

PubMed publication ID

29729422

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6777740&resulttype=core&format=json