(Q89414089)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034760%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

title

Insulin resistance in Alzheimer's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034760%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

1 reference

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034760%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

Thomas Diehl

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034760%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

Dimitrios Kapogiannis

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034760%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

publication date

13 December 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034760%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

published in

Translational Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034760%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

volume

183

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034760%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

page(s)

26-40

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034760%20AND%20SRC:MED&resulttype=core&format=json

The molecular basis of insulin-stimulated glucose uptake: signalling, trafficking and potential drug targets

4 April 2020

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Raptor binds the SAIN (Shc and IRS-1 NPXY binding) domain of insulin receptor substrate-1 (IRS-1) and regulates the phosphorylation of IRS-1 at Ser-636/639 by mTOR

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Signaling pathways in insulin action: molecular targets of insulin resistance

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Insulin signaling diverges into Akt-dependent and -independent signals to regulate the recruitment/docking and the fusion of GLUT4 vesicles to the plasma membrane

7 January 2021

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Insulin Signaling in Microdomains of the Plasma Membrane

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The SLC2 (GLUT) family of membrane transporters

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Insulin-independent glucose transport regulates insulin sensitivity

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Regulation of glucose transport by insulin: traffic control of GLUT4.

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GLUT4 glucose transporter expression in rodent brain: effect of diabetes

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7 January 2021

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The facilitative glucose transporter GLUT3: 20 years of distinction

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Neurobarrier coupling in the brain: adjusting glucose entry with demand

7 January 2021

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Localization of brain endothelial luminal and abluminal transporters with immunogold electron microscopy

7 January 2021

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Insulin binding to brain capillaries is reduced in genetically obese, hyperinsulinemic Zucker rats

7 January 2021

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Impaired insulin action in the human brain: causes and metabolic consequences

7 January 2021

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Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease

7 January 2021

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The human blood-brain barrier glucose transporter (GLUT1) is a glucose transporter of gray matter astrocytes

7 January 2021

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Insulin resistance: definition and consequences

7 January 2021

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Pathogenesis of type 2 diabetes mellitus

7 January 2021

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Insulin receptor serine kinase activation by casein kinase 2 and a membrane tyrosine kinase

7 January 2021

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APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor

7 January 2021

1 reference

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Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2

7 January 2021

1 reference

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Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

7 January 2021

1 reference

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Phosphorylation of IRS proteins, insulin action, and insulin resistance

7 January 2021

1 reference

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Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action

7 January 2021

1 reference

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Insulin-induced insulin receptor substrate-1 degradation is mediated by the proteasome degradation pathway.

7 January 2021

1 reference

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Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation

7 January 2021

1 reference

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Repeatability and reproducibility of the hyperinsulinemic-euglycemic clamp and the tracer dilution technique in a controlled inpatient setting

7 January 2021

1 reference

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Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

7 January 2021

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Pathogenesis of type 2 diabetes mellitus

7 January 2021

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Insulin action and insulin resistance: diseases involving defects in insulin receptors, signal transduction, and the glucose transport effector system.

7 January 2021

1 reference

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Free fatty acids repress the GLUT4 gene expression in cardiac muscle via novel response elements

7 January 2021

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Skeletal muscle insulin resistance: roles of fatty acid metabolism and exercise

7 January 2021

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Skeletal muscle triglyceride levels are inversely related to insulin action.

7 January 2021

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Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial function

7 January 2021

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Cellular mechanisms of insulin resistance in humans

7 January 2021

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Mechanism of free fatty acid-induced insulin resistance in humans

7 January 2021

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Protein O-GlcNAcylation in diabetes and diabetic complications

7 January 2021

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Identification of the major site of O-linked beta-N-acetylglucosamine modification in the C terminus of insulin receptor substrate-1.

7 January 2021

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Insulin resistance: a metabolic pathway to chronic liver disease

7 January 2021

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Insulin resistance in nonalcoholic fatty liver disease.

7 January 2021

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Is hepatic glucose production increased in type 2 diabetes mellitus?

7 January 2021

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NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome

7 January 2021

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The pro- and anti-inflammatory properties of the cytokine interleukin-6.

7 January 2021

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Interleukin-6 induces cellular insulin resistance in hepatocytes

7 January 2021

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Enhancement of beta-amyloid precursor protein transcription and expression by the soluble interleukin-6 receptor/interleukin-6 complex.

7 January 2021

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Interleukin-6 and α-2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices

7 January 2021

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Interleukin-6, a major cytokine in the central nervous system

7 January 2021

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Tumor necrosis factor alpha inhibits signaling from the insulin receptor

7 January 2021

1 reference

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Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease

7 January 2021

1 reference

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Insulin in the brain: its pathophysiological implications for States related with central insulin resistance, type 2 diabetes and Alzheimer's disease

7 January 2021

1 reference

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Identification of insulin in rat brain

7 January 2021

1 reference

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Insulin regulates brain function, but how does it get there?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

The effect of insulin on in vivo cerebral glucose concentrations and rates of glucose transport/metabolism in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin in the brain: there and back again

7 January 2021

1 reference

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Concentrations of insulin and insulin receptors in the brain are independent of peripheral insulin levels. Studies of obese and streptozotocin-treated rodents

7 January 2021

1 reference

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Human blood-brain barrier insulin receptor

7 January 2021

1 reference

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Hyperinsulinemia drives diet-induced obesity independently of brain insulin production

7 January 2021

1 reference

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Insulin receptors are widely distributed in the central nervous system of the rat

7 January 2021

1 reference

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Structural and functional characteristics of insulin receptors in rat neuroblastoma cells

7 January 2021

1 reference

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Brain insulin signaling: a key component of cognitive processes and a potential basis for cognitive impairment in type 2 diabetes

7 January 2021

1 reference

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How does brain insulin resistance develop in Alzheimer's disease?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin signaling in the central nervous system: learning to survive

7 January 2021

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Maternal insulin sensitivity is associated with oral glucose-induced changes in fetal brain activity.

7 January 2021

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Genetic variants in the Fat and Obesity Associated (FTO) gene and risk of Alzheimer's disease

7 January 2021

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7 January 2021

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Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase A-dependent mechanism.

7 January 2021

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An Obesity Risk SNP (rs17782313) near the MC4R Gene Is Associated with Cerebrocortical Insulin Resistance in Humans

7 January 2021

1 reference

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Signaling crosstalk between NF-kappaB and JNK.

7 January 2021

1 reference

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The role of fatty acids in insulin resistance

7 January 2021

1 reference

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Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

7 January 2021

1 reference

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Alterations of insulin signaling in type 2 diabetes: a review of the current evidence from humans

7 January 2021

1 reference

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Irs1 serine 307 promotes insulin sensitivity in mice

7 January 2021

1 reference

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Defining high-fat-diet rat models: metabolic and molecular effects of different fat types

7 January 2021

1 reference

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Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice

7 January 2021

1 reference

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High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin-resistant brain state after intracerebroventricular streptozotocin injection exacerbates Alzheimer-like changes in Tg2576 AbetaPP-overexpressing mice

7 January 2021

1 reference

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Insulin deficiency exacerbates cerebral amyloidosis and behavioral deficits in an Alzheimer transgenic mouse model

7 January 2021

1 reference

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Immunological analysis of glucose transporters expressed in different regions of the rat brain and central nervous system

7 January 2021

1 reference

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Intracerebroventricular Streptozotocin Injections as a Model of Alzheimer's Disease: in Search of a Relevant Mechanism

7 January 2021

1 reference

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Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Positional cloning of the mouse obese gene and its human homologue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Leptin treatment ameliorates anxiety in ob/ob obese mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

7 January 2021

1 reference

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Hyperglycemia-induced tau cleavage in vitro and in vivo: a possible link between diabetes and Alzheimer's disease.

7 January 2021

1 reference

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Liraglutide improves hippocampal synaptic plasticity associated with increased expression of Mash1 in ob/ob mice.

7 January 2021

1 reference

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Cognitive and emotional alterations are related to hippocampal inflammation in a mouse model of metabolic syndrome.

7 January 2021

1 reference

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Neurobehavioral deficits in db/db diabetic mice

7 January 2021

1 reference

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Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes.

7 January 2021

1 reference

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Dysfunctional pro-ceramide, ER stress, and insulin/IGF signaling networks with progression of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

What is oxidative stress?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior

7 January 2021

1 reference

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Oxidative stress, glutamate, and neurodegenerative disorders

7 January 2021

1 reference

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Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Involvement of oxidative stress in Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Enhanced oxidative stress is an early event during development of Alzheimer-like pathologies in presenilin conditional knock-out mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin neuroprotection against oxidative stress in cortical neurons--involvement of uric acid and glutathione antioxidant defenses.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Neuroprotection of insulin against oxidative stress-induced apoptosis in cultured retinal neurons: involvement of phosphoinositide 3-kinase/Akt signal pathway

7 January 2021

1 reference

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Oxidative stress and insulin resistance: the coronary artery risk development in young adults study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

The molecular basis for oxidative stress-induced insulin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Platelet activation in obese women: role of inflammation and oxidant stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Dietary intake of antioxidants and risk of Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Smoking and risk of dementia and Alzheimer's disease in a population-based cohort study: the Rotterdam Study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Caloric intake and the risk of Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Biology of Amyloid: Structure, Function, and Regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Cerebrospinal fluid protein biomarkers for Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Physiological roles for amyloid beta peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin increases CSF Abeta42 levels in normal older adults

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

JNK3 perpetuates metabolic stress induced by Aβ peptides.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

7 January 2021

inferred from DOI database lookup

Amyloid beta oligomers induce impairment of neuronal insulin receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Proteolytic degradation of amyloid β-protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

beta-Amyloid degradation and Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Structure, function, and regulation of insulin-degrading enzyme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin Resistance is Associated with Higher Cerebrospinal Fluid Tau Levels in Asymptomatic APOEɛ4 Carriers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin-degrading enzyme, apolipoprotein E, and Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Functional interactions of tau and their relevance for Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin-like growth factor-1 and insulin mediate transient site-selective increases in tau phosphorylation in primary cortical neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Akt/PKB kinase phosphorylates separately Thr212 and Ser214 of tau protein in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Interactions between glycogen synthase kinase 3beta, protein kinase B, and protein phosphatase 2A in tau phosphorylation in mouse N2a neuroblastoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Phosphatase activity toward abnormally phosphorylated tau: decrease in Alzheimer disease brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

PP2A mRNA expression is quantitatively decreased in Alzheimer's disease hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Deregulation of protein phosphatase 2A and hyperphosphorylation of τ protein following onset of diabetes in NOD mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

An anatomically comprehensive atlas of the adult human brain transcriptome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Multi-scale correlation structure of gene expression in the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Regional cerebral glucose transport and utilization in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Categorical and correlational analyses of baseline fluorodeoxyglucose positron emission tomography images from the Alzheimer's Disease Neuroimaging Initiative (ADNI).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Association of Insulin Resistance With Cerebral Glucose Uptake in Late Middle-Aged Adults at Risk for Alzheimer Disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin resistance predicts medial temporal hypermetabolism in mild cognitive impairment conversion to Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Glucose intolerance, insulin resistance, and pathological features of Alzheimer disease in the Baltimore Longitudinal Study of Aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Amyloid, hypometabolism, and cognition in Alzheimer disease: an [11C]PIB and [18F]FDG PET study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin resistance predicts brain amyloid deposition in late middle-aged adults.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Distinct tau PET imaging patterns in typical and atypical Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Monitoring the progression of Alzheimer's disease with τ-PET.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Brain aging in very old men with type 2 diabetes: the Honolulu-Asia Aging Study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin resistance, brain atrophy, and cognitive performance in late middle-aged adults

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Brain iron overload, insulin resistance, and cognitive performance in obese subjects: a preliminary MRI case-control study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Evaluation of two-dimensional L-COSY and JPRESS using a 3 T MRI scanner: from phantoms to human brain in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Diffusion imaging changes in grey matter in Alzheimer's disease: a potential marker of early neurodegeneration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

White matter changes in preclinical Alzheimer's disease: a magnetic resonance imaging-diffusion tensor imaging study on cognitively normal older people with positive amyloid β protein 42 levels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Correlation between cognitive function and the association fibers in patients with Alzheimer's disease using diffusion tensor imaging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Microstructural changes in the hippocampus and posterior cingulate in mild cognitive impairment and Alzheimer's disease: a diffusion tensor imaging study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Microstructural white matter abnormalities in type 2 diabetes mellitus: a diffusion tensor imaging study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Microstructural white matter abnormalities and cognitive functioning in type 2 diabetes: a diffusion tensor imaging study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

A Diffusion Tensor Imaging Study on White Matter Abnormalities in Patients with Type 2 Diabetes Using Tract-Based Spatial Statistics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin resistance and amyloidogenesis as common molecular foundation for type 2 diabetes and Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Aberrant brain functional connectivity related to insulin resistance in type 2 diabetes: a resting-state fMRI study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Resting-state brain functional connectivity is altered in type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin is differentially related to cognitive decline and atrophy in Alzheimer's disease and aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Cerebrospinal fluid insulin levels increase during intravenous insulin infusions in man

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Adiponectin and resistin in human cerebrospinal fluid and expression of adiponectin receptors in the human hypothalamus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin Resistance is Associated with Increased Levels of Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Reduced Memory Function in At-Risk Healthy Middle-Aged Adults

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin in central nervous system: more than just a peripheral hormone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

The exosome secretory pathway transports amyloid precursor protein carboxyl-terminal fragments from the cell into the brain extracellular space

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Alzheimer's disease beta-amyloid peptides are released in association with exosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Astrocytes secrete exosomes enriched with proapoptotic ceramide and prostate apoptosis response 4 (PAR-4): potential mechanism of apoptosis induction in Alzheimer disease (AD).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Proteins recruited to exosomes by tau overexpression implicate novel cellular mechanisms linking tau secretion with Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Insulin-degrading enzyme sorting in exosomes: a secretory pathway for a key brain amyloid-beta degrading protease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Exosomes as mediators of neuroinflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Emergence of exosomal miRNAs as a diagnostic biomarker for Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Low neural exosomal levels of cellular survival factors in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Intranasal insulin administration dose-dependently modulates verbal memory and plasma amyloid-beta in memory-impaired older adults.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Sex and ApoE genotype differences in treatment response to two doses of intranasal insulin in adults with mild cognitive impairment or Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Long-acting intranasal insulin detemir improves cognition for adults with mild cognitive impairment or early-stage Alzheimer's disease dementia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

The mode of action of thiazolidinediones

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Rosiglitazone and pioglitazone for the treatment of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

PPARgamma agonists as therapeutics for the treatment of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

PPARgamma inhibits NF-kappaB-dependent transcriptional activation in skeletal muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Long-term pioglitazone treatment improves learning and attenuates pathological markers in a mouse model of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Effect of pioglitazone medication on the incidence of dementia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Pharmacology, physiology, and mechanisms of incretin hormone action

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

GLP-1 receptor agonists: a review of head-to-head clinical studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

The nature, significance, and glucagon-like peptide-1 analog treatment of brain insulin resistance in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces Alzheimer disease-associated tau hyperphosphorylation in the hippocampus of rats with type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Exendin-4, a new peptide from Heloderma suspectum venom, potentiates cholecystokinin-induced amylase release from rat pancreatic acini

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Exenatide and the treatment of patients with Parkinson's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRSL.2016.12.005

Relationship between plasma and cerebrospinal fluid insulin levels of dogs

7 January 2021

1 reference

12 December 2020

Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling.

1 reference

12 December 2020

Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice.

1 reference

12 December 2020

What is oxidative stress?

1 reference

12 December 2020

Brain glucose transporters: relationship to local energy demand.

1 reference

12 December 2020

Insulin receptor signaling. Activation of multiple serine kinases

1 reference

12 December 2020

Insulin gene expression and insulin synthesis in mammalian neuronal cells

1 reference

12 December 2020

CSF and Brain Indices of Insulin Resistance, Oxidative Stress and Neuro-Inflammation in Early versus Late Alzheimer's Disease

1 reference

12 December 2020

Progressive coma after the transsphenoidal decompression of a pituitary adenoma with marked suprasellar extension: report of two cases

1 reference

12 December 2020

The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas

1 reference

12 December 2020

GSK-3β, a pivotal kinase in Alzheimer disease.

1 reference

12 December 2020

Insulin-degrading enzyme

1 reference

12 December 2020

Exendin-4, a glucagon-like peptide-1 receptor agonist prevents mTBI-induced changes in hippocampus gene expression and memory deficits in mice

1 reference

12 December 2020

Insulin-sensitive GLUT4 glucose transporters are colocalized with GLUT3-expressing cells and demonstrate a chemically distinct neuron-specific localization in rat brain

1 reference

12 December 2020

Localization of insulin and type 1 IGF receptors in rat brain by in vitro autoradiography and in situ hybridization

1 reference

12 December 2020

Clearance of Alzheimer's Abeta peptide: the many roads to perdition.

1 reference

12 December 2020

How free fatty acids inhibit glucose utilization in human skeletal muscle

1 reference

12 December 2020

Sniffing neuropeptides: a transnasal approach to the human brain

1 reference

12 December 2020

Antioxidant effects of statins

1 reference

12 December 2020

Desensitization of brain insulin receptor. Effect on glucose/energy and related metabolism.

1 reference

12 December 2020

Transient hypoxia causes Alzheimer-type molecular and biochemical abnormalities in cortical neurons: potential strategies for neuroprotection.

1 reference

12 December 2020

10.1016/J.TRSL.2016.12.005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034760%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034760%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

PubMed publication ID

28034760

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28034760%20AND%20SRC:MED&resulttype=core&format=json