(Q54231304)

26 May 2018

title

Unveiling benznidazole's mechanism of action through overexpression of DNA repair proteins in Trypanosoma cruzi. (English)

1 reference

26 May 2018

0 references

1 reference

María Cristina M Motta

1 reference

26 May 2018

Angela Kaysel Cruz

Angela Kaysel Cruz

Marisa Helena Gennari de Medeiros

0 references

Marisa Helena Gennari de Medeiros

0 references

Glória Regina Franco

1 reference

26 May 2018

Santuza M R Teixeira

Santuza Maria Ribeiro Teixeira

1 reference

26 May 2018

Carlos Renato Machado

Carlos Renato Machado

1 reference

26 May 2018

Marianna Kunrath-Lima

Marianna Kunrath-Lima

1 reference

26 May 2018

Nadja C Souza-Pinto

Nadja Cristhina de Souza-Pinto

1 reference

26 May 2018

author name string

Matheus Andrade Rajão

1 reference

26 May 2018

Carolina Furtado

1 reference

26 May 2018

Ceres Luciana Alves

1 reference

26 May 2018

Danielle Gomes Passos-Silva

1 reference

26 May 2018

Michelle Barbi de Moura

1 reference

26 May 2018

Bruno Luiz Schamber-Reis

1 reference

26 May 2018

Aline Araújo Zuma

1 reference

26 May 2018

João Pedro Vieira-da-Rocha

1 reference

26 May 2018

Juliana Borio Ferreira Garcia

1 reference

26 May 2018

Isabela Cecília Mendes

1 reference

26 May 2018

Sérgio Danilo Junho Pena

1 reference

26 May 2018

Andrea Mara Macedo

1 reference

26 May 2018

publication date

18 December 2013

1 reference

26 May 2018

Environmental and Molecular Mutagenesis

published in

1 reference

26 May 2018

volume

1 reference

26 May 2018

issue

1 reference

26 May 2018

page(s)

309-321

1 reference

26 May 2018

Oxidative stress and DNA lesions: the role of 8-oxoguanine lesions in Trypanosoma cruzi cell viability.

cites work

1 reference

Ovothiol and trypanothione as antioxidants in trypanosomatids

21 January 2018

1 reference

Immunological and clinical evaluation of chagasic patients subjected to chemotherapy during the acute phase of Trypanosoma cruzi infection 14-30 years ago

21 January 2018

1 reference

Repair and genetic consequences of endogenous DNA base damage in mammalian cells

21 January 2018

1 reference

Adaptation to DNA damage and stimulation of genetic instability: the double-edged sword mammalian DNA polymerase kappa

21 January 2018

1 reference

Characterization of the 'unusual' mobility of large circular DNAs in pulsed field-gradient electrophoresis

21 January 2018

1 reference

Trypanosoma cruzi MSH2: Functional analyses on different parasite strains provide evidences for a role on the oxidative stress response.

21 January 2018

1 reference

The mammalian mismatch repair pathway removes DNA 8-oxodGMP incorporated from the oxidized dNTP pool

21 January 2018

1 reference

A critical review on Chagas disease chemotherapy

21 January 2018

1 reference

Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics

21 January 2018

1 reference

Functional characterization of 8-oxoguanine DNA glycosylase of Trypanosoma cruzi

21 January 2018

1 reference

Chagas disease: "the new HIV/AIDS of the Americas"

21 January 2018

1 reference

Network news: the replication of kinetoplast DNA.

21 January 2018

1 reference

Formation of 2-hydroxydeoxyadenosine triphosphate, an oxidatively damaged nucleotide, and its incorporation by DNA polymerases. Steady-state kinetics of the incorporation

21 January 2018

1 reference

Homologous recombination in DNA repair and DNA damage tolerance

21 January 2018

1 reference

Biochemical studies with DNA polymerase beta and DNA polymerase beta-PAK of Trypanosoma cruzi suggest the involvement of these proteins in mitochondrial DNA maintenance

21 January 2018

1 reference

Characterization of the recombinant MutY homolog, an adenine DNA glycosylase, from yeast Schizosaccharomyces pombe

21 January 2018

1 reference

MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis

21 January 2018

1 reference

Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host.

21 January 2018

1 reference

Hydrolytic elimination of a mutagenic nucleotide, 8-oxodGTP, by human 18-kilodalton protein: sanitization of nucleotide pool

21 January 2018

1 reference

Cloning and characterization of DNA polymerase eta from Trypanosoma cruzi: roles for translesion bypass of oxidative damage

21 January 2018

1 reference

Distinct acetylation of Trypanosoma cruzi histone H4 during cell cycle, parasite differentiation, and after DNA damage.

21 January 2018

1 reference

Time-dependent oxidative stress caused by benznidazole

21 January 2018

1 reference

DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition

21 January 2018

1 reference

Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function

21 January 2018

1 reference

Oxidation in the nucleotide pool, the DNA damage response and cellular senescence: Defective bricks build a defective house

21 January 2018

1 reference

DNA polymerase kappa from Trypanosoma cruzi localizes to the mitochondria, bypasses 8-oxoguanine lesions and performs DNA synthesis in a recombination intermediate

21 January 2018

1 reference

21 January 2018

1 reference

Characterization of the Trypanosoma cruzi Rad51 gene and its role in recombination events associated with the parasite resistance to ionizing radiation

21 January 2018

1 reference

DNA repair in mammalian cells: Base excision repair: the long and short of it.

21 January 2018

1 reference

Trypanosoma brucei has two distinct mitochondrial DNA polymerase beta enzymes

21 January 2018

1 reference

DNA polymerase beta from Trypanosoma cruzi is involved in kinetoplast DNA replication and repair of oxidative lesions.

21 January 2018

1 reference

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

21 January 2018

1 reference

Oxidative stress and antioxidant defenses: a target for the treatment of diseases caused by parasitic protozoa

21 January 2018

1 reference

The Role of Glutathione Peroxidases in Trypanosomatids

21 January 2018

1 reference

A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes

21 January 2018

1 reference

Base excision repair by hNTH1 and hOGG1: a two edged sword in the processing of DNA damage in gamma-irradiated human cells

21 January 2018

1 reference

Effect of topoisomerase inhibitors and DNA-binding drugs on the cell proliferation and ultrastructure of Trypanosoma cruzi.

21 January 2018

1 reference

Expression of exogenous genes in Trypanosoma cruzi: improving vectors and electroporation protocols

21 January 2018

1 reference

7 January 2021

Effects of buthionine sulfoximine nifurtimox and benznidazole upon trypanothione and metallothionein proteins in Trypanosoma cruzi

1 reference

7 January 2021

The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)

1 reference

7 January 2021

Different behaviors of benznidazole as free radical generator with mammalian and Trypanosoma cruzi microsomal preparations

1 reference

7 January 2021

Improved genomic/nuclear DNA extraction for 8-hydroxydeoxyguanosine analysis of small amounts of rat liver tissue

1 reference

7 January 2021

Mode of action of the 2-nitroimidazole derivative benznidazole

1 reference

7 January 2021

Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells

1 reference

7 January 2021

A DNA polymerase beta in the mitochondrion of the trypanosomatid Crithidia fasciculata

1 reference

7 January 2021

DNA damage induced by reduced nitroimidazole drugs

1 reference

7 January 2021

Identifiers

DOI

10.1002/EM.21839

1 reference

26 May 2018

1 reference

26 May 2018