(Q52098330)

22 April 2018

title

Active recruitment of DNA methyltransferases regulates interleukin 4 in thymocytes and T cells (English)

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27 March 2024

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27 March 2024

author name string

Mercedes Pérez-Melgosa

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22 April 2018

Maria Shnyreva

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22 April 2018

Karen W. Makar

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14595437

27 March 2024

William M. Weaver

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14595437

27 March 2024

David R. Fitzpatrick

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14595437

27 March 2024

Christopher B. Wilson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14595437

27 March 2024

language of work or name

English

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publication date

2 November 2003

1 reference

22 April 2018

full work available at URL

http://www.nature.com/articles/ni1004.pdf

file format

Portable Document Format

1 reference

http://www.nature.com/articles/ni1004

27 March 2024

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27 March 2024

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22 April 2018

volume

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22 April 2018

issue

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22 April 2018

page(s)

1183-1190

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22 April 2018

Chromatin structure and gene regulation in the immune system

cites work

1 reference

7 January 2021

The lineage decisions of helper T cells

1 reference

7 January 2021

Transcription: tantalizing times for T cells

1 reference

7 January 2021

An epigenetic view of helper T cell differentiation

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7 January 2021

Stability and commitment in T helper cell development

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7 January 2021

T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes

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7 January 2021

In TH2 cells the Il4 gene has a series of accessibility states associated with distinctive probabilities of IL-4 production.

1 reference

7 January 2021

Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene.

1 reference

7 January 2021

DNA methylation changes at human Th2 cytokine genes coincide with DNase I hypersensitive site formation during CD4(+) T cell differentiation.

1 reference

7 January 2021

Cutting edge: changes in histone acetylation at the IL-4 and IFN-gamma loci accompany Th1/Th2 differentiation

1 reference

7 January 2021

Gene silencing quantitatively controls the function of a developmental trans-activator

1 reference

7 January 2021

DNA methylation patterns and epigenetic memory

1 reference

7 January 2021

Methylation-induced repression--belts, braces, and chromatin

1 reference

7 January 2021

The role of DNA methylation in mammalian epigenetics

1 reference

7 January 2021

Chromatin modification and epigenetic reprogramming in mammalian development

1 reference

7 January 2021

DNA methylation in animal development

1 reference

7 January 2021

A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

1 reference

7 January 2021

GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells

1 reference

7 January 2021

Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level

1 reference

7 January 2021

Signaling and transcription in T helper development

1 reference

7 January 2021

T cell differentiation: a mechanistic view

1 reference

7 January 2021

Th2-specific DNase I-hypersensitive sites in the murine IL-13 and IL-4 intergenic region.

1 reference

7 January 2021

Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects

1 reference

7 January 2021

Translating the Histone Code

1 reference

7 January 2021

Histone methylation in transcriptional control

1 reference

7 January 2021

Histone H3 lysine 4 methylation disrupts binding of nucleosome remodeling and deacetylase (NuRD) repressor complex

1 reference

7 January 2021

An epigenetic road map for histone lysine methylation

1 reference

7 January 2021

Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases

1 reference

7 January 2021

A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

1 reference

7 January 2021

Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin

1 reference

7 January 2021

Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation

1 reference

7 January 2021

A novel transcription factor, T-bet, directs Th1 lineage commitment

1 reference

7 January 2021

Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

1 reference

7 January 2021

The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.

1 reference

7 January 2021

Helper T cell differentiation, inside and out.

1 reference

7 January 2021

Mammalian (cytosine-5) methyltransferases cause genomic DNA methylation and lethality in Drosophila.

1 reference

7 January 2021

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

1 reference

7 January 2021

Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process

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7 January 2021

The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation

1 reference

7 January 2021

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

1 reference

7 January 2021

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

1 reference

7 January 2021

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

1 reference

7 January 2021

The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase

1 reference

7 January 2021

Histone modification and replacement in chromatin activation

1 reference

7 January 2021

Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation

1 reference

7 January 2021

Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.

1 reference

7 January 2021

The role of DNA methylation in setting up chromatin structure during development

1 reference

7 January 2021

Distinct methylation of the interferon gamma (IFN-gamma) and interleukin 3 (IL-3) genes in newly activated primary CD8+ T lymphocytes: regional IFN-gamma promoter demethylation and mRNA expression are heritable in CD44(high)CD8+ T cells

1 reference

7 January 2021

Two waves of nuclear factor kappaB recruitment to target promoters

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7 January 2021

Identifiers

DOI

10.1038/NI1004

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22 April 2018

1 reference

22 April 2018