(Q50111962)

25 February 2018

title

T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes (English)

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25 February 2018

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25 February 2018

Anjana Rao

object named as

Anjana Rao

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25 February 2018

Laurie Glimcher

object named as

Laurie H Glimcher

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25 February 2018

author name string

Orly Avni

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25 February 2018

Dong Lee

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25 February 2018

Susanne J Szabo

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25 February 2018

language of work or name

English

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publication date

10 June 2002

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25 February 2018

published in

Nature Immunology

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25 February 2018

volume

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25 February 2018

issue

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25 February 2018

page(s)

643-651

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25 February 2018

Functional diversity of helper T lymphocytes

cites work

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7 January 2021

The biology of Stat4 and Stat6

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7 January 2021

Signaling and transcription in T helper development

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7 January 2021

Helper T cell differentiation, inside and out.

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7 January 2021

T cell differentiation: a mechanistic view

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7 January 2021

The molecular basis of T helper 1 and T helper 2 cell differentiation

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7 January 2021

Th2 lineage commitment and efficient IL-4 production involves extended demethylation of the IL-4 gene.

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7 January 2021

Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation

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7 January 2021

Th2-specific DNase I-hypersensitive sites in the murine IL-13 and IL-4 intergenic region.

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7 January 2021

Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo

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7 January 2021

Deletion of a coordinate regulator of type 2 cytokine expression in mice

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7 January 2021

Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence Comparisons

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7 January 2021

A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells

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7 January 2021

Translating the Histone Code

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7 January 2021

Histone methylation versus histone acetylation: new insights into epigenetic regulation

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7 January 2021

The language of covalent histone modifications

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7 January 2021

Signaling to chromatin through histone modifications

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7 January 2021

Histone acetyltransferases

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7 January 2021

Cytokine transcriptional events during helper T cell subset differentiation

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7 January 2021

Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells

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7 January 2021

GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells

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7 January 2021

Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment.

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7 January 2021

The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.

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7 January 2021

Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun.

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7 January 2021

A novel transcription factor, T-bet, directs Th1 lineage commitment

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7 January 2021

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

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7 January 2021

The relationship of IL-4- and IFNγ-producing T cells studied by lineage ablation of IL-4-producing cells

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7 January 2021

Conventional, naive CD4+ T cells provide an initial source of IL-4 during Th2 differentiation

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7 January 2021

Stat6 regulation of in vivo IL-4 responses

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7 January 2021

Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.

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7 January 2021

Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling

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7 January 2021

Nuclear factor of activated T cells (NFAT)-dependent transactivation regulated by the coactivators p300/CREB-binding protein (CBP)

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7 January 2021

CBP/p300 Integrates Raf/Rac-Signaling Pathways in the Transcriptional Induction of NF-ATc during T Cell Activation

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7 January 2021

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

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7 January 2021

Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin

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7 January 2021

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

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7 January 2021

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

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7 January 2021

Essential role of Stat6 in IL-4 signalling

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7 January 2021

Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

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7 January 2021

Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile

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7 January 2021

p300/CBP is required for transcriptional induction by interleukin-4 and interacts with Stat6.

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7 January 2021

Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3

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7 January 2021

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

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7 January 2021

Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

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7 January 2021

Cutting edge: chromatin remodeling at the IL-4/IL-13 intergenic regulatory region for Th2-specific cytokine gene cluster

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7 January 2021

PU.1 and GATA: components of a mast cell-specific interleukin 4 intronic enhancer

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7 January 2021

Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level

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7 January 2021

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

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7 January 2021

Murine interleukin-4 displays potent anti-tumor activity in vivo

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7 January 2021

Virus infection leads to localized hyperacetylation of histones H3 and H4 at the IFN-beta promoter

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7 January 2021

The cyclosporin-sensitive transcription factor NFATp is expressed in several classes of cells in the immune system

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7 January 2021

Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes

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7 January 2021

Identifiers

DOI

10.1038/NI808

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25 February 2018

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25 February 2018