(Q48355959)

10 February 2018

title

VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death (English)

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10 February 2018

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David Gozal

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10 February 2018

Baolin Li

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10 February 2018

Wei Xu

series ordinal

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10 February 2018

Chun Luo

series ordinal

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10 February 2018

Rugao Liu

series ordinal

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10 February 2018

publication date

1 March 2003

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10 February 2018

published in

Molecular Brain Research

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10 February 2018

volume

111

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10 February 2018

issue

1-2

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10 February 2018

page(s)

155-164

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10 February 2018

PTEN function in mammalian cell size regulation

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Akt activation by growth factors is a multiple-step process: the role of the PH domain

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Adaptive resistance to nitric oxide in motor neurons

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7 January 2021

Elevated "hydroxyl radical" generation in vivo in an animal model of amyotrophic lateral sclerosis.

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7 January 2021

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

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7 January 2021

Impaired tolerance to repetitive hypoxia in hippocampal slices of Cu,Zn superoxide dismutase transgenic mice.

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7 January 2021

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

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7 January 2021

Cell cycle and death control: long live Forkheads

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7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

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7 January 2021

Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons

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7 January 2021

A recombinant adenovirus expressing p27Kip1 induces cell cycle arrest and loss of cyclin-Cdk activity in human breast cancer cells

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7 January 2021

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

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7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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7 January 2021

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

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7 January 2021

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

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7 January 2021

Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis

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7 January 2021

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

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7 January 2021

Reduction of ischemic damage by application of vascular endothelial growth factor in rat brain after transient ischemia

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7 January 2021

Rapid induction of vascular endothelial growth factor gene expression after transient middle cerebral artery occlusion in rats

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7 January 2021

Role of mitogen- and stress-activated kinases in ischemic injury

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7 January 2021

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

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7 January 2021

Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia

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7 January 2021

Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo

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7 January 2021

Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat

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7 January 2021

Induction of vascular endothelial growth factor receptors and phosphatidylinositol 3'-kinase/Akt signaling by global cerebral ischemia in the rat

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7 January 2021

Vascular permeability factor, an endothelial cell mitogen related to PDGF

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7 January 2021

Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress

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7 January 2021

Vascular endothelial growth factor is a secreted angiogenic mitogen

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7 January 2021

Intracellular generation of free radicals and modifications of detoxifying enzymes in cultured neurons from the developing rat forebrain in response to transient hypoxia

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7 January 2021

Enhanced oxygen radical production in a transgenic mouse model of familial amyotrophic lateral sclerosis

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7 January 2021

Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1-mediated motor neuron cell death and increase amyotrophic lateral sclerosis-like transgenic mouse survival

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7 January 2021

Neuronal death in newborn striatum after hypoxia-ischemia is necrosis and evolves with oxidative stress

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7 January 2021

Vascular endothelial growth factor rescues hippocampal neurons from glutamate-induced toxicity: signal transduction cascades.

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7 January 2021

Vascular endothelial growth factor mediates reactive angiogenesis in the postnatal developing brain

1 reference

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7 January 2021

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2803%2900025-1

7 January 2021

Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2803%2900025-1

7 January 2021

Akt phosphorylation and neuronal survival after traumatic brain injury in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2803%2900025-1

7 January 2021

Mitogen-activated protein kinases and cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2803%2900025-1

7 January 2021

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2803%2900025-1

7 January 2021

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

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7 January 2021

Intracellular signaling pathways activated by neurotrophic factors

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7 January 2021

Vascular, glial and neuronal effects of vascular endothelial growth factor in mesencephalic explant cultures

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7 January 2021

Hypoxia and Lou Gehrig

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2803%2900025-1

7 January 2021

Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system

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7 January 2021

Signaling pathways for PC12 cell differentiation: making the right connections

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7 January 2021

Second-generation adenovirus vectors

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7 January 2021

Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2803%2900025-1

7 January 2021

Neuroprotection by hypoxic preconditioning requires sequential activation of vascular endothelial growth factor receptor and Akt.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2803%2900025-1

7 January 2021

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2803%2900025-1

7 January 2021

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2803%2900025-1

7 January 2021

Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2803%2900025-1

7 January 2021

A familial amyotrophic lateral sclerosis-associated A4V Cu, Zn-superoxide dismutase mutant has a lower Km for hydrogen peroxide. Correlation between clinical severity and the Km value.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2803%2900025-1

7 January 2021

10.1016/S0169-328X(03)00025-1

Identifiers

DOI

1 reference

10 February 2018

1 reference

10 February 2018