(Q94029459)

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Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease

scientific article published in December 2001

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12 May 2020

Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease (English)

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12 May 2020

amyotrophic lateral sclerosis

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M Nagai

1

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12 May 2020

M Aoki

2

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12 May 2020

I Miyoshi

3

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12 May 2020

M Kato

4

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12 May 2020

P Pasinelli

5

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12 May 2020

N Kasai

6

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12 May 2020

R H Brown

7

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12 May 2020

Y Itoyama

8

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12 May 2020

publication date

1 December 2001

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12 May 2020

Journal of Neuroscience

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12 May 2020

21

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12 May 2020

23

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12 May 2020

9246-9254

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12 May 2020

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Delaying caspase activation by Bcl-2: A clue to disease retardation in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

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Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mut

1 reference

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Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis

1 reference

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Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

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Neurobiology. Stay the executioner's hand

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Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

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From Charcot to SOD1: mechanisms of selective motor neuron death in ALS.

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11 February 2021

Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase.

1 reference

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Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS.

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Glutamate, excitotoxicity and amyotrophic lateral sclerosis

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11 February 2021

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

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11 February 2021

Epidemiology of mutations in superoxide dismutase in amyotrophic lateral sclerosis

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11 February 2021

Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis

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11 February 2021

Intense superoxide dismutase-1 immunoreactivity in intracytoplasmic hyaline inclusions of familial amyotrophic lateral sclerosis with posterior column involvement

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11 February 2021

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

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Plasmids with a kanamycin-resistance gene for site-directed mutagenesis using the oligodeoxyribonucleotide-directed dual amber method

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Localized proton MR spectroscopy of the brain in children

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11 February 2021

Ubiquitin-positive inclusion in anterior horn cells in subgroups of motor neuron diseases: a comparative study of adult-onset amyotrophic lateral sclerosis, juvenile amyotrophic lateral sclerosis and Werdnig-Hoffmann disease

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11 February 2021

Fasting plasma and CSF amino acid levels in amyotrophic lateral sclerosis: a subtype analysis.

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Mild ALS in Japan associated with novel SOD mutation

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

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A new bacteriophage P1-derived vector for the propagation of large human DNA fragments

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11 February 2021

Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

1 reference

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Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice

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Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis

1 reference

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Cu/Zn superoxide dismutase-like immunoreactivity in Lewy body-like inclusions of sporadic amyotrophic lateral sclerosis

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Ubiquitin deposits in anterior horn cells in motor neurone disease.

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Cytopathology of amyotrophic lateral sclerosis

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Atomic structures of wild-type and thermostable mutant recombinant human Cu,Zn superoxide dismutase

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11 February 2021

Identifiers

10.1523/JNEUROSCI.21-23-09246.2001

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11717358%20AND%20SRC:MED&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11717358%20AND%20SRC:MED&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11717358%20AND%20SRC:MED&resulttype=core&format=json

12 May 2020

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