(Q48089465)

8 February 2018

title

Intraneuronal amyloid-beta plays a role in mediating the synergistic pathological effects of apoE4 and environmental stimulation (English)

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8 February 2018

author name string

Ofir Levi

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8 February 2018

Iftach Dolev

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8 February 2018

Haim Belinson

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8 February 2018

Daniel M Michaelson

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8 February 2018

language of work or name

English

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publication date

31 July 2007

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8 February 2018

Journal of Neurochemistry

published in

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8 February 2018

volume

103

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8 February 2018

issue

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8 February 2018

page(s)

1031-1040

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8 February 2018

Environmental enrichment improves cognition in aged Alzheimer's transgenic mice despite stable beta-amyloid deposition.

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Role of apoE/Abeta interactions in Alzheimer's disease: insights from transgenic mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

A nontransgenic mouse model shows inducible amyloid-beta (Abeta) peptide deposition and elucidates the role of apolipoprotein E in the amyloid cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Reduced hippocampal neurogenesis in R6/2 transgenic Huntington's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Has the amyloid cascade hypothesis for Alzheimer's disease been proved?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice: apoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Reelin, lipoprotein receptors and synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

In vivo effects of ApoE and clusterin on amyloid-beta metabolism and neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

APP processing and synaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Education and the prevalence of dementia and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Neurodegenerative tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

ApoE4 impairs hippocampal plasticity isoform-specifically and blocks the environmental stimulation of synaptogenesis and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Abeta-42 deposition precedes other changes in PS-1 Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Apolipoprotein (apo) E4 and Alzheimer's disease: unique conformational and biophysical properties of apoE4 can modulate neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

ApoE and Abeta1-42 interactions: effects of isoform and conformation on structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Alzheimer's centennial legacy: prospects for rational therapeutic intervention targeting the Abeta amyloid pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Enriched environment and spatial learning enhance hippocampal neurogenesis and salvages ischemic penumbra after focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Accelerated hippocampal atrophy in Alzheimer's disease with apolipoprotein E epsilon4 allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Role of apolipoprotein E in modulating neurite outgrowth: potential effect of intracellular apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Susceptibility of transgenic mice expressing human apolipoprotein E to closed head injury: the allele E3 is neuroprotective whereas E4 increases fatalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

ApoE-dependent plasticity in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Human apolipoprotein E isoform-specific differences in neuronal sprouting in organotypic hippocampal culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Amyloid precursor protein overexpression depresses excitatory transmission through both presynaptic and postsynaptic mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Neural consequences of environmental enrichment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Impaired neuronal plasticity in transgenic mice expressing human apolipoprotein E4 compared to E3 in a model of entorhinal cortex lesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Long-term effects of cognitive training on everyday functional outcomes in older adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23 model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: apoE structure as a potential therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

LRP and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04810.X

10.1111/J.1471-4159.2007.04810.X

21 January 2018

Identifiers

DOI

1 reference

8 February 2018

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8 February 2018