(Q42139164)

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IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo

scientific article published on 27 April 2006

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1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo (English)

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Europe PubMed Central

PMC publication ID

17 October 2017

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Emmanuel Zorn

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Europe PubMed Central

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17 October 2017

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Jerome Ritz

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Europe PubMed Central

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17 October 2017

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Haesook Kim

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Europe PubMed Central

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17 October 2017

Robert J Soiffer

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Robert J Soiffer

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Europe PubMed Central

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17 October 2017

Fabrice Porcheray

4

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Fabrice Porcheray

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Europe PubMed Central

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17 October 2017

6

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Despina Litsa

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Mehrdad Mohseni

3

object named as

Mehrdad Mohseni

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

author name string

Erik A Nelson

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1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Roberto Bellucci

7

1 reference

Europe PubMed Central

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17 October 2017

Elke Raderschall

8

1 reference

Europe PubMed Central

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17 October 2017

Christine Canning

9

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Europe PubMed Central

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17 October 2017

David A Frank

11

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Europe PubMed Central

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17 October 2017

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publication date

27 April 2006

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Europe PubMed Central

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17 October 2017

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Europe PubMed Central

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17 October 2017

108

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Europe PubMed Central

PMC publication ID

17 October 2017

5

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

1571-1579

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients

1 reference

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Dendritic cell immunizations alone or combined with low doses of interleukin-2 induce specific immune responses in melanoma patients

1 reference

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Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

1 reference

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29 May 2018

Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen

1 reference

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A function for interleukin 2 in Foxp3-expressing regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895505

29 May 2018

Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus

1 reference

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IL-15 but not IL-2 rapidly induces lethal xenogeneic graft-versus-host disease.

1 reference

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29 May 2018

Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease

1 reference

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In vivo expansion of CD4CD45RO-CD25 T cells expressing foxP3 in IL-2-treated HIV-infected patients

1 reference

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Regulatory T cell lineage specification by the forkhead transcription factor foxp3

1 reference

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29 May 2018

Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period

1 reference

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29 May 2018

Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

1 reference

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Immunologic and clinical outcomes of vaccination with a multiepitope melanoma peptide vaccine plus low-dose interleukin-2 administered either concurrently or on a delayed schedule

1 reference

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29 May 2018

Isolation of unique STAT5 targets by chromatin immunoprecipitation-based gene identification

1 reference

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29 May 2018

Tolerance, not immunity, crucially depends on IL-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895505

29 May 2018

Interleukin-2 is essential for CD4+CD25+ regulatory T cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895505

29 May 2018

Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895505

29 May 2018

IL-2, regulatory T cells, and tolerance

1 reference

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29 May 2018

Dynamic changes of specific T cell responses to melanoma correlate with IL-2 administration

1 reference

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29 May 2018

Control of autoimmunity by naturally arising regulatory CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895505

29 May 2018

Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895505

29 May 2018

Loss of Tolerance and Autoimmunity Affecting Multiple Organs inSTAT5A/5B-Deficient Mice

1 reference

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29 May 2018

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895505

29 May 2018

Control of regulatory T cell development by the transcription factor Foxp3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895505

29 May 2018

Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation

1 reference

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29 May 2018

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

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29 May 2018

Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 receptor and STAT4.

1 reference

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The Jak-STAT pathway

1 reference

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Stat3 as an oncogene

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Characterization of cytokine differential induction of STAT complexes in primary human T and NK cells

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Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation

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Interleukin 2 signaling involves the phosphorylation of Stat proteins

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Essential Role for STAT5 Signaling in CD25+CD4+ Regulatory T Cell Homeostasis and the Maintenance of Self-Tolerance

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https://pubmed.ncbi.nlm.nih.gov/16645171

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Clinical and immunologic effects of prolonged infusion of low-dose recombinant interleukin-2 after autologous and T-cell-depleted allogeneic bone marrow transplantation

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Effect of low-dose interleukin-2 on disease relapse after T-cell-depleted allogeneic bone marrow transplantation

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inferred from PubMed ID database lookup

Expansion and manipulation of natural killer cells in patients with metastatic cancer by low-dose continuous infusion and intermittent bolus administration of interleukin 2

1 reference

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inferred from PubMed ID database lookup

Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells

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Identifiers

10.1182/BLOOD-2006-02-004747

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

ResearchGate publication ID

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