(Q28590646)

31 January 2017

title

A function for interleukin 2 in Foxp3-expressing regulatory T cells (English)

1 reference

Cytotoxic T-lymphocyte-associated protein 4

31 January 2017

0 references

1 reference

Integrin alpha E, epithelial-associated

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Tumor necrosis factor receptor superfamily, member 18

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Inducible T cell co-stimulator

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Forkhead box P3

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Selectin, lymphocyte

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Interleukin 2

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Interleukin 2 receptor, gamma chain

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Interleukin 2 receptor, beta chain

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Interleukin 2 receptor, alpha chain

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CD69 antigen

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Alexander Y. Rudensky

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31 January 2017

Marc A. Gavin

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31 January 2017

Jason D. Fontenot

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31 January 2017

Jeffrey P. Rasmussen

series ordinal

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31 January 2017

language of work or name

English

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publication date

1 November 2005

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31 January 2017

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31 January 2017

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31 January 2017

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31 January 2017

page(s)

1142–1151

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Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

31 January 2017

cites work

1 reference

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

21 April 2017

1 reference

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

21 April 2017

1 reference

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

21 April 2017

1 reference

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

21 April 2017

1 reference

Gene ontology: tool for the unification of biology

21 April 2017

1 reference

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

21 April 2017

1 reference

Bioconductor: open software development for computational biology and bioinformatics

21 April 2017

1 reference

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

21 April 2017

1 reference

Interleukin-2: inception, impact, and implications

21 April 2017

1 reference

7 January 2021

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

1 reference

7 January 2021

IL-2, regulatory T cells, and tolerance

1 reference

7 January 2021

Tolerance, not immunity, crucially depends on IL-2.

1 reference

7 January 2021

CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2

1 reference

7 January 2021

Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period

1 reference

7 January 2021

Interleukin 2 signaling is required for CD4(+) regulatory T cell function

1 reference

7 January 2021

Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers

1 reference

7 January 2021

CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion

1 reference

7 January 2021

Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

1 reference

7 January 2021

Interleukin-2 is essential for CD4+CD25+ regulatory T cell function

1 reference

7 January 2021

Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function

1 reference

7 January 2021

A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3.

1 reference

7 January 2021

Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism

1 reference

7 January 2021

Human T regulatory cells can use the perforin pathway to cause autologous target cell death

1 reference

7 January 2021

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

1 reference

7 January 2021

Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease

1 reference

7 January 2021

An integral role for heme oxygenase-1 and carbon monoxide in maintaining peripheral tolerance by CD4+CD25+ regulatory T cells

1 reference

7 January 2021

Soluble fibrinogen-like protein 2/fibroleukin exhibits immunosuppressive properties: suppressing T cell proliferation and inhibiting maturation of bone marrow-derived dendritic cells

1 reference

7 January 2021

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

1 reference

7 January 2021

Normal lymphoid homeostasis and lack of lethal autoimmunity in mice containing mature T cells with severely impaired IL-2 receptors

1 reference

7 January 2021

Homeostasis of T cell numbers: from thymus production to peripheral compartmentalization and the indexation of regulatory T cells

1 reference

7 January 2021

CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

1 reference

7 January 2021

T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells

1 reference

7 January 2021

TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

1 reference

7 January 2021

The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response

1 reference

7 January 2021

Essential Role for STAT5 Signaling in CD25+CD4+ Regulatory T Cell Homeostasis and the Maintenance of Self-Tolerance

1 reference

7 January 2021

Loss of Tolerance and Autoimmunity Affecting Multiple Organs inSTAT5A/5B-Deficient Mice

1 reference

7 January 2021