(Q41616341)

English

Cooperative binding of Smad proteins to two adjacent DNA elements in the plasminogen activator inhibitor-1 promoter mediates transforming growth factor beta-induced smad-dependent transcriptional activation

scientific article published on April 1999

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1 reference

Europe PubMed Central

PubMed publication ID

5 October 2017

Cooperative binding of Smad proteins to two adjacent DNA elements in the plasminogen activator inhibitor-1 promoter mediates transforming growth factor beta-induced smad-dependent transcriptional activation (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 October 2017

1 reference

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author name string

Stroschein SL

1

1 reference

Europe PubMed Central

PubMed publication ID

5 October 2017

Wang W

2

1 reference

Europe PubMed Central

PubMed publication ID

5 October 2017

Luo K

3

1 reference

Europe PubMed Central

PubMed publication ID

5 October 2017

language of work or name

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publication date

1 April 1999

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Europe PubMed Central

PubMed publication ID

5 October 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

5 October 2017

274

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Europe PubMed Central

PubMed publication ID

5 October 2017

14

1 reference

Europe PubMed Central

PubMed publication ID

5 October 2017

9431-9441

1 reference

Europe PubMed Central

PubMed publication ID

5 October 2017

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

A transforming growth factor beta type I receptor that signals to activate gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Positive and negative regulation of type II TGF-beta receptor signal transduction by autophosphorylation on multiple serine residues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Mechanism of activation of the TGF-beta receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

A human Mad protein acting as a BMP-regulated transcriptional activator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Smad4 and FAST-1 in the assembly of activin-responsive factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

A transcriptional partner for MAD proteins in TGF-beta signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Human Smad3 and Smad4 are sequence-specific transcription activators

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Smad4/DPC4 and Smad3 mediate transforming growth factor-beta (TGF-beta) signaling through direct binding to a novel TGF-beta-responsive element in the human plasminogen activator inhibitor-1 promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

TGF beta signals through a heteromeric protein kinase receptor complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Type 1 plasminogen activator inhibitor gene: functional analysis and glucocorticoid regulation of its promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Production of high-titer helper-free retroviruses by transient transfection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

An AP-1 binding sequence is essential for regulation of the human alpha2(I) collagen (COL1A2) promoter activity by transforming growth factor-beta.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

A structural basis for mutational inactivation of the tumour suppressor Smad4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor beta transcriptional responses in endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9431

21 January 2018

Identifiers

10.1074/JBC.274.14.9431

1 reference

Europe PubMed Central

PubMed publication ID

5 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 October 2017

ResearchGate publication ID

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