(Q45345228)

13 December 2017

title

Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4 (English)

1 reference

12 September 2024

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9214507

12 September 2024

tumor suppressor gene

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9214507

12 September 2024

D. Wotton

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9214507

12 September 2024

G. Lagna

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9214507

12 September 2024

J. Massagué

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9214507

12 September 2024

A. Hata

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9214507

12 September 2024

R. S. Lo

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9214507

12 September 2024

language of work or name

English

0 references

publication date

1 July 1997

1 reference

13 December 2017

3 July 1997

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9214507

full work available at URL

12 September 2024

https://www.nature.com/articles/40424.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9214507

https://www.nature.com/articles/40424.pdf

12 September 2024

file format

Portable Document Format

1 reference

https://www.nature.com/articles/40424

12 September 2024

1 reference

http://www.nature.com/doifinder/10.1038/40424

12 September 2024

1 reference

12 September 2024

1 reference

13 December 2017

volume

388

1 reference

13 December 2017

issue

6637

1 reference

13 December 2017

page(s)

82-87

1 reference

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

13 December 2017

cites work

1 reference

7 January 2021

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

1 reference

7 January 2021

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

1 reference

7 January 2021

A human Mad protein acting as a BMP-regulated transcriptional activator

1 reference

7 January 2021

A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

1 reference

7 January 2021

TGF-beta signalling through the Smad pathway

1 reference

7 January 2021

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

1 reference

7 January 2021

1 reference

7 January 2021

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

1 reference

7 January 2021

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

1 reference

7 January 2021

Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

1 reference

7 January 2021

A structural basis for mutational inactivation of the tumour suppressor Smad4

1 reference

7 January 2021

Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin

1 reference

7 January 2021

Mad-related genes in the human

1 reference

7 January 2021

Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily

1 reference

7 January 2021

Mammalian Ras interacts directly with the serine/threonine kinase Raf

1 reference

7 January 2021

Mechanism of activation of the TGF-beta receptor

1 reference

7 January 2021

Inhibition of activin receptor signaling promotes neuralization in Xenopus

1 reference

7 January 2021

2527

M Schutte

1996

1 reference

12 September 2024

2519

SK Kim

1996

1 reference

12 September 2024

2718

M Nagatake

1996

1 reference

12 September 2024

4351

MT Barrett

1996

1 reference

12 September 2024

5583

K Uchida

1996

1 reference

12 September 2024

Identifiers

DOI

10.1038/40424

1 reference

Dimensions Publication ID

13 December 2017

1030141911

0 references

1 reference