(Q40399370)

20 September 2017

title

Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways (English)

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20 September 2017

Gregg L Semenza

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20 September 2017

Marcin Kortylewski

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20 September 2017

Qing Xu

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20 September 2017

Jon Briggs

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20 September 2017

Sungman Park

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20 September 2017

Guilian Niu

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20 September 2017

Shumin Zhang

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20 September 2017

Tanya Gritsko

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20 September 2017

James Turkson

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20 September 2017

Heidi Kay

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20 September 2017

Jin Q Cheng

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20 September 2017

Richard Jove

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20 September 2017

Hua Yu

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20 September 2017

language of work or name

English

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publication date

1 August 2005

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20 September 2017

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20 September 2017

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20 September 2017

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20 September 2017

page(s)

5552-5560

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Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal

20 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208719

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

21 January 2018

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Transcription factors as targets for cancer therapy

21 January 2018

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VEGF and the quest for tumour angiogenesis factors

21 January 2018

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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

21 January 2018

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Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208719

HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas.

21 January 2018

1 reference

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Advances in biology of multiple myeloma: clinical applications

21 January 2018

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Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208719

VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic beta cell carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208719

Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells

21 January 2018

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Activated pp60c-Src leads to elevated hypoxia-inducible factor (HIF)-1alpha expression under normoxia

21 January 2018

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Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity

21 January 2018

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HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

21 January 2018

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Roles of activated Src and Stat3 signaling in melanoma tumor cell growth

21 January 2018

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Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

21 January 2018

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Tyrosine kinase receptor-activated signal transduction pathways which lead to oncogenesis.

21 January 2018

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Oncogenes as inducers of tumor angiogenesis

21 January 2018

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JAKs, STATs and Src kinases in hematopoiesis

21 January 2018

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Oncostatin-M induction of vascular endothelial growth factor expression in astroglioma cells

21 January 2018

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Targeting HIF-1 for cancer therapy

21 January 2018

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Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

21 January 2018

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Regulation of tumor angiogenesis by integrin-linked kinase (ILK).

21 January 2018

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Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation

21 January 2018

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

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Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208719

Constitutive and inducible expression and regulation of vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208719

Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208719

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

21 January 2018

1 reference

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The STATs of cancer--new molecular targets come of age

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208719

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208719

Phosphorylation of STAT-3 in response to basic fibroblast growth factor occurs through a mechanism involving platelet-activating factor, JAK-2, and Src in human umbilical vein endothelial cells. Evidence for a dual kinase mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208719

7 January 2021

The pathophysiologic role of VEGF in hematologic malignancies: therapeutic implications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208719

7 January 2021

Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208719

7 January 2021

Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208719

7 January 2021

VEGF differentially activates STAT3 in microvascular endothelial cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1038/SJ.ONC.1208719

Identifiers

DOI

10.1038/SJ.ONC.1208719

1 reference

Dimensions Publication ID

20 September 2017

1044728544

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1 reference