(Q43761443)

26 November 2017

title

Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma (English)

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26 November 2017

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T Hideshima

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26 November 2017

N Nakamura

series ordinal

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26 November 2017

D Chauhan

series ordinal

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26 November 2017

K C Anderson

series ordinal

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26 November 2017

language of work or name

English

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publication date

1 September 2001

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26 November 2017

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26 November 2017

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26 November 2017

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26 November 2017

page(s)

5991-6000

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Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

26 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

RAFTK/PYK2-dependent and -independent apoptosis in multiple myeloma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Interleukin-6 activates phosphatidylinositol-3 kinase, which inhibits apoptosis in human prostate cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Insulin-like growth factor induces the survival and proliferation of myeloma cells through an interleukin-6-independent transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Kinases: positive and negative regulators of apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Stimulation of protein synthesis, eukaryotic translation initiation factor 4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate 1 and phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Oncostatin M, leukemia inhibitory factor, and interleukin 6 induce the proliferation of human plasmacytoma cells via the common signal transducer, gp130.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Akt regulates cell survival and apoptosis at a postmitochondrial level

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Phosphorylation and regulation of Raf by Akt (protein kinase B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Inhibition of the Phosphoinositide 3-Kinase Pathway Induces a Senescence-like Arrest Mediated by p27Kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

Mechanism of activation of protein kinase B by insulin and IGF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

7 January 2021

Tyrosine phosphorylation of JAK-TYK kinases in malignant plasma cell lines growth-stimulated by interleukins 6 and 11

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

7 January 2021

Apaf-1/cytochrome c-independent and Smac-dependent induction of apoptosis in multiple myeloma (MM) cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

7 January 2021

Cytochrome c-dependent and -independent induction of apoptosis in multiple myeloma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

7 January 2021

Dexamethasone induces apoptosis of multiple myeloma cells in a JNK/SAP kinase independent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

7 January 2021

Interleukin-6 inhibits transforming growth factor-beta-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

7 January 2021

Interleukin-6 inhibits apoptosis of malignant plasma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

7 January 2021

Activation of phosphatidylinositol 3-kinase through glycoprotein 130 induces protein kinase B and p70 S6 kinase phosphorylation in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204833

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204833

1 reference

Dimensions Publication ID

26 November 2017

1020861000

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1 reference