(Q39075901)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24144410%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Selection and optimization of hits from a high-throughput phenotypic screen against Trypanosoma cruzi (English)

1 reference

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28 February 2020

0 references

1 reference

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28 February 2020

Jean-Robert Ioset

1 reference

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28 February 2020

Martine Keenan

1 reference

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28 February 2020

Paul W Alexander

1 reference

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28 February 2020

Jason H Chaplin

1 reference

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28 February 2020

Michael J Abbott

1 reference

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28 February 2020

Hugo Diao

1 reference

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28 February 2020

Zhisen Wang

1 reference

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28 February 2020

Wayne M Best

1 reference

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28 February 2020

Catherine J Perez

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28 February 2020

Scott M J Cornwall

1 reference

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28 February 2020

Sarah K Keatley

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28 February 2020

R C Andrew Thompson

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28 February 2020

Karen L White

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28 February 2020

Eileen Ryan

1 reference

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28 February 2020

Gong Chen

1 reference

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28 February 2020

Thomas W von Geldern

1 reference

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28 February 2020

Eric Chatelain

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28 February 2020

publication date

1 October 2013

1 reference

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Future Medicinal Chemistry

28 February 2020

published in

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28 February 2020

volume

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28 February 2020

issue

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28 February 2020

page(s)

1733-1752

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Chagas disease has now gone global

28 February 2020

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Activities of the triazole derivative SCH 56592 (posaconazole) against drug-resistant strains of the protozoan parasite Trypanosoma (Schizotrypanum) cruzi in immunocompetent and immunosuppressed murine hosts

21 January 2018

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In vitro and in vivo activities of ravuconazole on Trypanosoma cruzi, the causative agent of Chagas disease

21 January 2018

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Chemotherapy with benznidazole and itraconazole for mice infected with different Trypanosoma cruzi clonal genotypes

21 January 2018

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Parasitological cure of acute and chronic experimental Chagas disease using the long-acting experimental triazole TAK-187. Activity against drug-resistant Trypanosoma cruzi strains

21 January 2018

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21 January 2018

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Effects of ravuconazole treatment on parasite load and immune response in dogs experimentally infected with Trypanosoma cruzi.

21 January 2018

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Efficacy of voriconazole in a murine model of acute Trypanosoma cruzi infection

21 January 2018

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21 January 2018

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21 January 2018

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Analogues of fenarimol are potent inhibitors of Trypanosoma cruzi and are efficacious in a murine model of Chagas disease

21 January 2018

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Design, structure-activity relationship and in vivo efficacy of piperazine analogues of fenarimol as inhibitors of Trypanosoma cruzi.

21 January 2018

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Benznidazole-resistance in Trypanosoma cruzi is a readily acquired trait that can arise independently in a single population

21 January 2018

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The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications

21 January 2018

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Unequivocal identification of subpopulations in putative multiclonal Trypanosoma cruzi strains by FACs single cell sorting and genotyping

21 January 2018

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Trypanosoma cruzi isolates from Chile are heterogeneous and composed of mixed populations when characterized by schizodeme and Southern analyses.

21 January 2018

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Discovery of a Novel Class of Orally Active Trypanocidal N -Myristoyltransferase Inhibitors

21 January 2018

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Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs

21 January 2018

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N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

21 January 2018

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The Alamar Blue assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro

21 January 2018

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21 January 2018

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Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease

21 January 2018

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Activity in vivo of anti-Trypanosoma cruzi compounds selected from a high throughput screening

21 January 2018

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Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign

21 January 2018

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