(Q28484826)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

Fexinidazole: a potential new drug candidate for Chagas disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

0 references

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

author name string

Maria Terezinha Bahia

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Isabel Mayer de Andrade

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Tassiane Assíria Fontes Martins

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Álvaro Fernando da Silva do Nascimento

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Lívia de Figueiredo Diniz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Ivo Santana Caldas

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Bernadette Bourdin Trunz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Els Torreele

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Isabela Ribeiro

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

language of work or name

English

0 references

publication date

1 November 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

PLoS Neglected Tropical Diseases

17 February 2020

published in

1 reference

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17 February 2020

volume

1 reference

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17 February 2020

issue

1 reference

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17 February 2020

page(s)

e1870

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 2.5 Generic

17 February 2020

0 references

on focus list of Wikimedia project

ScienceSource

0 references

cites work

Fexinidazole--a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Treatment with benznidazole during the chronic phase of experimental Chagas' disease decreases cardiac alterations

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Chronic phase of Chagas disease: why should it be treated? A comprehensive review

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Potential new drugs for human African trypanosomiasis: some progress at last

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Cross-resistance to nitro drugs and implications for treatment of human African trypanosomiasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

New drugs against tuberculosis: problems, progress, and evaluation of agents in clinical development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Activity of the new triazole derivative albaconazole against Trypanosoma (Schizotrypanum) cruzi in dog hosts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Rapid quantitation of Trypanosoma cruzi in host tissue by real-time PCR.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Chemotherapy with benznidazole and itraconazole for mice infected with different Trypanosoma cruzi clonal genotypes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Activities of the triazole derivative SCH 56592 (posaconazole) against drug-resistant strains of the protozoan parasite Trypanosoma (Schizotrypanum) cruzi in immunocompetent and immunosuppressed murine hosts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Metronidazole. A therapeutic review and update

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

The activity of fexinidazole (HOE 239) against experimental infections with Trypanosoma cruzi, trichomonads and Entamoeba histolytica

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Trypanosoma cruzi benznidazole susceptibility in vitro does not predict the therapeutic outcome of human Chagas disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Effects of ravuconazole treatment on parasite load and immune response in dogs experimentally infected with Trypanosoma cruzi.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Susceptibility and natural resistance of Trypanosoma cruzi strains to drugs used clinically in Chagas disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Schizodeme analysis of Trypanosoma cruzi stocks from South and Central America by analysis of PCR-amplified minicircle variable region sequences

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Enzyme immunoassays in diagnostic medicine. Theory and practice

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

New advances in the management of a long-neglected disease

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001870

Ergosterol biosynthesis and drug development for Chagas disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001870

Trypanosoma cruzi: acute and long-term infection in the vertebrate host can modify the response to benznidazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001870

Trypanosoma cruzi: optimization of polymerase chain reaction for detection in human blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001870

Vascular and cellular responses to pro-inflammatory stimuli in rat dental pulp

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001870

Benznidazole therapy during acute phase of Chagas disease reduces parasite load but does not prevent chronic cardiac lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001870

Genotoxicity profile of fexinidazole--a drug candidate in clinical development for human African trypanomiasis (sleeping sickness).

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Trypanosoma cruzi reinfections in mice determine the severity of cardiac damage

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486905

Chemotherapeutically effective nitro compounds. 3rd communication: nitropyridines, nitroimidazopyridines and related compounds (author's transl)

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23133682

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PNTD.0001870

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

23133682

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23133682%20AND%20SRC:MED&resulttype=core&format=json