(Q36719185)

English

Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP.

scientific article published on 24 April 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP. (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Crohn's disease

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susceptibility locus

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based on heuristic

inferred from title

ulcerative colitis

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based on heuristic

inferred from title

15

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Europe PubMed Central

PMC publication ID

15 August 2017

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Gosia Trynka

4

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Alexandra Zhernakova

object named as

Alexandra Zhernakova

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David A van Heel

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David A van Heel

12

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object named as

Lude Franke

3

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Rinse K Weersma

17

object named as

Rinse K Weersma

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Pieter C F Stokkers

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object named as

Pieter C F Stokkers

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Europe PubMed Central

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15 August 2017

Alienke J Wijmenga-Monsuur

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Alienke J Monsuur

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Europe PubMed Central

PMC publication ID

15 August 2017

Marianna R Bevova

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Marianna Bevova

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Europe PubMed Central

PMC publication ID

15 August 2017

Adriaan A van Bodegraven

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object named as

Adriaan A van Bodegraven

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Europe PubMed Central

PMC publication ID

15 August 2017

J Bart A Crusius

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object named as

J Bart A Crusius

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Europe PubMed Central

PMC publication ID

15 August 2017

Cleo C van Diemen

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object named as

Cleo C van Diemen

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Eleanora A. Festen

2

object named as

Eleanora M Festen

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Ruben van 't Slot

9

object named as

Ruben van 't Slot

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

H Marike Boezen

11

object named as

H Marike Boezen

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

author name string

Rian M Nijmeijer

8

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Europe PubMed Central

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15 August 2017

Roel Heijmans

10

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Europe PubMed Central

PMC publication ID

15 August 2017

language of work or name

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publication date

24 April 2008

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Europe PubMed Central

PMC publication ID

15 August 2017

American Journal of Human Genetics

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Europe PubMed Central

PMC publication ID

15 August 2017

82

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Europe PubMed Central

PMC publication ID

15 August 2017

5

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Europe PubMed Central

PMC publication ID

15 August 2017

1202-1210

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Newly identified genetic risk variants for celiac disease related to the immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

New links to the pathogenesis of Crohn disease provided by genome-wide association scans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

Innate immunity in inflammatory bowel disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

A second generation human haplotype map of over 3.1 million SNPs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

A genome-wide association study of global gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

The IL23 axis plays a key role in the pathogenesis of IBD.

1 reference

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30 September 2017

Inflammasomes in inflammatory disorders: the role of TLRs and their interactions with NLRs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

Unravelling the pathogenesis of inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma

1 reference

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30 September 2017

A new multipoint method for genome-wide association studies by imputation of genotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

Critical role of toll-like receptors and nucleotide oligomerisation domain in the regulation of health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

Contribution of the novel inflammatory bowel disease gene IL23R to disease susceptibility and phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

Nod-like proteins in immunity, inflammation and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

Genetic variation in myosin IXB is associated with ulcerative colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

New insights into the regulation of TLR signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

Serologically defined colon cancer antigen 3 is necessary for the presentation of TNF receptor 1 on cell surface

1 reference

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30 September 2017

How Toll-like receptors and Nod-like receptors contribute to innate immunity in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

Commentary: the role of the IL-18 system and other members of the IL-1R/TLR superfamily in innate mucosal immunity and the pathogenesis of inflammatory bowel disease: friend or foe?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

Haploview: analysis and visualization of LD and haplotype maps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

IL-18 receptor beta-induced changes in the presentation of IL-18 binding sites affect ligand binding and signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

The G-protein regulator AGS3 controls an early event during macroautophagy in human intestinal HT-29 cells.

1 reference

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30 September 2017

Inflammatory Bowel Disease

1 reference

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30 September 2017

Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: blocking interleukin 18 attenuates intestinal damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

IL-18-binding protein expression by endothelial cells and macrophages is up-regulated during active Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

30 September 2017

Role of Toll-like receptors in health and diseases of gastrointestinal tract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

28 June 2018

Analysis of a positional candidate gene for inflammatory bowel disease: NRAMP2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

28 June 2018

Incidence and prevalence of ulcerative colitis and Crohn's disease in the County of Copenhagen, 1962 to 1978.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

28 June 2018

A disintegrin and metalloprotease 33 polymorphisms and lung function decline in the general population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

5 September 2018

Blockade of endogenous IL-18 ameliorates TNBS-induced colitis by decreasing local TNF-alpha production in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

5 September 2018

Bioactive IL-18 expression is up-regulated in Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

5 September 2018

Factors associated with bronchial responsiveness to histamine in a population sample of adults.

1 reference

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5 September 2018

CTLA4 is differentially associated with autoimmune diseases in the Dutch population

1 reference

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20 October 2018

ATG16L1andIL23RAre Associated With Inflammatory Bowel Diseases but Not With Celiac Disease in The Netherlands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

4 December 2018

The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

4 December 2018

All roads lead to CARD9

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

4 December 2018

The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

4 December 2018

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

4 December 2018

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427314

4 December 2018

Association between Toll-like receptor 4 and inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18439550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pair of 9s: it's in the CARDs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18439550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 18 is a potent proliferative factor for intestinal mucosal lymphocytes in Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18439550

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.AJHG.2008.03.016

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

ResearchGate publication ID

0 references

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