(Q28270603)

Mark J Daly

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Peter K. Gregersen

Peter K Gregersen

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Kent D Taylor

Kent D Taylor

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Stephan R. Targan

Stephan Targan

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Steven R. Brant

Steven R Brant

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Mark S. Silverberg

Mark S Silverberg

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Judy H. Cho

Judy H Cho

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Anne M. Griffiths

Anne Griffiths

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A Hillary Steinhart

A Hillary Steinhart

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Lisa Wu Datta

Lisa Wu Datta

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Miguel D Regueiro

Miguel Regueiro

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L Philip Schumm

L Philip Schumm

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Themistocles Dassopoulos

Themistocles Dassopoulos

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Huiying Yang

Huiying Yang

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Clara Abraham

Clara Abraham

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Emily Kistner-Griffin

Emily O Kistner

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Alain Bitton

Annette Jassies-van der Lee

Alain Bitton

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describes a project that uses

Annette T Lee

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language of work or name

English

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publication date

1 December 2006

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published in

Science

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volume

314

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issue

5804

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page(s)

1461-3

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genome-wide association study

1 reference

on focus list of Wikimedia project

inferred from title

ScienceSource

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cites work

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Transforming growth factor-beta induces development of the T(H)17 lineage

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Identification and expression analysis of alternatively spliced isoforms of human interleukin-23 receptor gene in normal lymphoid cells and selected tumor cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Anti-interleukin-12 antibody for active Crohn's disease

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Functional variants of OCTN cation transporter genes are associated with Crohn disease

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Inflammatory Bowel Disease

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

20 March 2017

1 reference

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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

20 March 2017

1 reference

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Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Increased expression of interleukin 17 in inflammatory bowel disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

7 April 2017

The genetics of health

1 reference

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IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Current status of genetics research in inflammatory bowel disease.

29 September 2017

1 reference

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Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4410764

Understanding the IL-23-IL-17 immune pathway

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17068223

12 December 2020

inferred from PubMed ID database lookup

Cutting edge: IL-23 cross-regulates IL-12 production in T cell-dependent experimental colitis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17068223

12 December 2020

inferred from PubMed ID database lookup

Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17068223

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1126/SCIENCE.1135245

1 reference

1 reference

1 reference

PubMed publication ID

17068223

1 reference